Activation of GRIK3 homomer

Stable Identifier
R-HSA-500717
Type
Reaction [transition]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane, cytosol
ReviewStatus
5/5
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Activation of GRIK3 homomer
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Kainate receptor activation activates G protein coupled receptors involving the release of Ca2+ from the intracellular stores. This activity of Kainate receptors is independent of ionic influx and regulates both glutamate release by the pyramidal neurons and gama-aminobutyric acid release by the internuerons.
Literature References
PubMed ID Title Journal Year
20007474 Atypical functional properties of GluK3-containing kainate receptors

Perrais, D, Coussen, F, Mulle, C

J Neurosci 2009
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Input
Output
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as an event of
Catalyst Activity

G protein-coupled receptor binding activity of GRIK3 homomer glutamate complex [plasma membrane]

Physical Entity
GRIK3 homomer glutamate complex [plasma membrane] (Homo sapiens)
Activity
G protein-coupled receptor binding (GO:0001664)
Orthologous Events
Activation of GRIK3 homomer (Bos taurus)
Activation of GRIK3 homomer (Canis familiaris)
Activation of GRIK3 homomer (Gallus gallus)
Activation of GRIK3 homomer (Mus musculus)
Authored
Mahajan, SS  (2010-02-05)
Reviewed
Tukey, D  (2009-11-18)
Created
Mahajan, SS  (2010-02-05)
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