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What is Reactome ?
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p-Y699-STAT5B [cytosol]
Stable Identifier
R-HSA-507939
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
p(Y699)-STAT5B, Signal transducer and activator of transcription 5B, STA5B_HUMAN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
FLT3 signaling in disease (Homo sapiens)
Signaling by FLT3 ITD and TKD mutants (Homo sapiens)
STAT5 activation downstream of FLT3 ITD mutants (Homo sapiens)
FLT3 ITD mutants phosphorylate STAT5 (Homo sapiens)
p-6Y FLT3 ITD mutant dimers:GRB2:p-Y GAB2:PTPN11:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
PTPN11:p-STAT5 dissociates from mutant FLT3 (Homo sapiens)
PTPN11:p-STAT5 [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-6Y FLT3 ITD mutant dimers:GRB2:p-Y GAB2:PTPN11:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
PTPN11:p-STAT5 translocates to nucleus downstream of mutant FLT3 (Homo sapiens)
PTPN11:p-STAT5 [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dissociates from mutant FLT3 (Homo sapiens)
p-6Y FLT3 ITD mutant dimers:GRB2:p-Y GAB2:PTPN11:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5 translocates to nucleus downstream of mutant FLT3 (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Signaling by FLT3 fusion proteins (Homo sapiens)
FLT3 fusions activate STAT5 (Homo sapiens)
p-Y FLT3 fusions:p-STAT5 [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dissociates from FLT3 fusion proteinsp- (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-Y FLT3 fusions:p-STAT5 [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5 translocates to nucleus downstream of mutant FLT3 (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Signaling by FGFR in disease (Homo sapiens)
Signaling by FGFR1 in disease (Homo sapiens)
FGFR1 mutant receptor activation (Homo sapiens)
Signaling by cytosolic FGFR1 fusion mutants (Homo sapiens)
Phosphorylation of STAT5 by cytosolic FGFR1 fusions (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Signaling by KIT in disease (Homo sapiens)
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants (Homo sapiens)
Dimerization of STATs downstream of KIT mutants (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STAT dimers [plasma membrane] (Homo sapiens)
p-STAT dimer [cytosol] (Homo sapiens)
p-STATs [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STATs [plasma membrane] (Homo sapiens)
p-STATs [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Disassociation and translocation of STATs to the nucleus downstream of KIT mutants (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STAT dimers [plasma membrane] (Homo sapiens)
p-STAT dimer [cytosol] (Homo sapiens)
p-STATs [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Phosphorylation of STATs downstream of KIT mutants (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STATs [plasma membrane] (Homo sapiens)
p-STATs [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
FLT3 Signaling (Homo sapiens)
STAT5 Activation (Homo sapiens)
Activator phosphorylates STAT5 (Homo sapiens)
Activators of STAT5:p-STAT5 [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dissociates from activator:STAT5 complex (Homo sapiens)
Activators of STAT5:p-STAT5 [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Growth hormone receptor signaling (Homo sapiens)
STAT5 dimers translocate to the nucleus (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
STAT5 tyrosine phosphorylation (Homo sapiens)
Growth Hormone:Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dimerizes (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5A/B dissociates from the Growth Hormone receptor (Homo sapiens)
Growth Hormone:Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Prolactin receptor signaling (Homo sapiens)
PRLR-bound STAT5 is phosphorylated (Homo sapiens)
PRLR ligands:p-Y611-PRLR:p-Y1007-JAK2 dimer:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Signaling by CSF3 (G-CSF) (Homo sapiens)
p-Y-STAT1,3,5 dimer translocates from the cytosol to the nucleoplasm (Homo sapiens)
p-Y-STAT1,3,5 dimer [cytosol] (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-Y-STAT1,3,5 dimerize (Homo sapiens)
p-Y-STAT1,3,5 dimer [cytosol] (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-2 family signaling (Homo sapiens)
Interleukin-2 signaling (Homo sapiens)
Phosphorylated STAT5 is released (Homo sapiens)
IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Recruited STAT5 is phosphorylated (Homo sapiens)
IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
STAT5 dimers translocate to the nucleus (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dimerizes (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Interleukin-21 signaling (Homo sapiens)
IL21 receptor STAT phosphorylation (Homo sapiens)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3:p-Y701-STAT1,p-Y705-STAT3,p-Y693-STAT4,(p-Y694-STAT5A,p-Y699-STAT5B) [plasma membrane] (Homo sapiens)
p-Y701-STAT1, p-Y705-STAT3,p-Y693-STAT4,(p-Y694-STAT5A,p-Y699-STAT5B) [cytosol] (Homo sapiens)
(p-Y694-STAT5A,p-Y699-STAT5B) [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Homo sapiens)
Activation of STAT5a/b by JAK2 (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
High affinity IL-5 receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
IL3:IL3R active complex, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
STAT5 dimers translocate to the nucleus (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dimerizes (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dissociates from the receptor complex (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
High affinity GM-CSF receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
High affinity IL-5 receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
IL3:IL3R active complex, activated JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Interleukin-7 signaling (Homo sapiens)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Homo sapiens)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
STAT5 dimers translocate to the nucleus (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dimerizes (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B (Homo sapiens)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Erythropoietin (Homo sapiens)
Erythropoietin activates STAT5 (Homo sapiens)
JAK2 and LYN phosphorylate STAT5 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 (Homo sapiens)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dissociates from EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 (Homo sapiens)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Signaling by Leptin (Homo sapiens)
JAK2 Phosphorylates STAT5 in Response to Leptin (Homo sapiens)
LEP:p-LEPR:p-JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Phosphorylated STAT5 Dissociates from Leptin Receptor (Homo sapiens)
LEP:p-LEPR:p-JAK2:p-STAT5 [plasma membrane] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
STAT5 dimers translocate to the nucleus (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5 dimerizes (Homo sapiens)
p-STAT5 dimer [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by SCF-KIT (Homo sapiens)
Dimerization of STATs (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] (Homo sapiens)
p-STAT dimer [cytosol] (Homo sapiens)
p-STATs [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] (Homo sapiens)
p-STATs [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Disassociation and translocation of STATs to the nucleus (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] (Homo sapiens)
p-STAT dimer [cytosol] (Homo sapiens)
p-STATs [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
Phosphorylation of STATs (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] (Homo sapiens)
p-STATs [cytosol] (Homo sapiens)
p-Y699-STAT5B [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P51692 STAT5B
Gene Names
STAT5B
Chain
chain:1-787
Reference Genes
BioGPS Gene:6777 STAT5B
COSMIC (genes):STAT5B STAT5B
CTD Gene:6777 STAT5B
dbSNP Gene:6777 STAT5B
ENSEMBL:ENSG00000173757 STAT5B
HGNC:11367 STAT5B
KEGG:hsa:6777 STAT5B
Monarch:6777 STAT5B
NCBI Gene:6777 STAT5B
OMIM:604260 STAT5B
UCSC:P51692 STAT5B
Reference Transcript
RefSeq:NM_012448.3 STAT5B
Other Identifiers
11720228_at
11720229_a_at
11759969_at
11759970_x_at
1555086_3p_at
1555086_PM_at
1555086_at
1555088_PM_x_at
1555088_x_at
16845096
205026_PM_at
205026_at
212549_PM_at
212549_at
212550_PM_at
212550_at
33869_at
3721664
3721670
3721671
3721672
3721673
3721680
3721687
3757768
3757769
3757771
3757772
3757773
3757774
3757775
3757776
3757777
3757778
3757779
3757780
3757781
3757782
3757783
3757784
3757785
3757786
3757787
3757788
3757789
3757790
3757791
3757793
3757794
3757795
3757796
3757797
3757798
3757799
3757800
3757801
3757803
3757804
3757805
3757807
3757808
3757811
3757812
3757824
472_at
473_g_at
6777
8015590
A_23_P100788
A_24_P342178
A_33_P3380867
GE56366
GE61443
GO:0000278
GO:0000785
GO:0000978
GO:0000981
GO:0001228
GO:0001553
GO:0001779
GO:0001787
GO:0002376
GO:0003677
GO:0003682
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0006629
GO:0006790
GO:0006952
GO:0007165
GO:0007166
GO:0007259
GO:0007548
GO:0007565
GO:0007595
GO:0008283
GO:0008284
GO:0012501
GO:0019218
GO:0019221
GO:0019530
GO:0019915
GO:0022414
GO:0030098
GO:0030154
GO:0030155
GO:0030183
GO:0030218
GO:0030856
GO:0032355
GO:0032743
GO:0032819
GO:0032825
GO:0032870
GO:0033028
GO:0033033
GO:0033077
GO:0035259
GO:0038162
GO:0040014
GO:0040018
GO:0042104
GO:0042127
GO:0042267
GO:0042448
GO:0042492
GO:0042802
GO:0042803
GO:0043029
GO:0043226
GO:0043434
GO:0045579
GO:0045588
GO:0045621
GO:0045647
GO:0045648
GO:0045931
GO:0045944
GO:0045954
GO:0046543
GO:0046544
GO:0046983
GO:0048541
GO:0048856
GO:0048870
GO:0050729
GO:0050798
GO:0060397
GO:0070669
GO:0070670
GO:0070672
GO:0071363
GO:0071364
GO:0090575
GO:0097531
GO:0098542
GO:0140110
HMNXSV003000956
HMNXSV003050236
Hs.24064.0.A1_3p_at
Hs.24064.0.A2_3p_at
ILMN_1684034
PH_hs_0025369
TC17001529.hg
U47686_s_at
U48730_at
g6912687_3p_at
Participates
as a candidate of
(p-Y694-STAT5A,p-Y699-STAT5B) [cytosol] (Homo sapiens)
as a member of
p-STAT5A, p-STAT5B [cytosol] (Homo sapiens)
p-STATs [cytosol] (Homo sapiens)
Other forms of this molecule
p-STAT5B [cytosol]
p-Y699-STAT5B [nucleoplasm]
STAT5B [cytosol]
Inferred To
phospho-Stat5b [cytosol]
(Mus musculus)
phospho-Stat5b [cytosol]
(Rattus norvegicus)
phospho-stat5a [cytosol]
(Danio rerio)
phospho-p-Y699-STAT5B [cytosol]
(Gallus gallus)
phospho-STAT5B [cytosol]
(Bos taurus)
phospho-STAT5B [cytosol]
(Canis familiaris)
phospho-STAT5B [cytosol]
(Sus scrofa)
phospho-stat5b [cytosol]
(Xenopus tropicalis)
phospho-Stat92E [cytosol]
(Drosophila melanogaster)
Modified Residues
Name
O4'-phospho-L-tyrosine at 699
Coordinate
699
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_036580.2
ENSEMBL
ENST00000698776
,
ENST00000698777
,
ENSP00000513923
,
ENST00000293328
,
ENSP00000398379
,
ENSP00000293328
,
ENST00000415845
,
ENSP00000513924
OpenTargets
ENSG00000173757
HPA
ENSG00000173757-STAT5B
ZINC - Substances
STA5B_HUMAN
ZINC target
P51692
PRO
P51692
Pharos - Targets
P51692
GlyGen
P51692
Orphanet
STAT5B
ZINC - Predictions - Purchasable
STA5B_HUMAN
PDB
6MBZ
,
6MBW
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13287 NMI
1
NMI [cytosol]
(R-HSA-9731022)
0.625
7
UniProt:P00519 ABL1
6
p-S456-ABL1 [nucleoplasm]
(R-HSA-5686576)
ABL1 [nucleoplasm]
(R-HSA-5686579)
p-Y226,Y393-ABL1 [cytosol]
(R-HSA-8942610)
ABL1 [cytosol]
(R-HSA-375987)
p-Y226,Y393-ABL1 [nucleoplasm]
(R-HSA-8985251)
p-Y393-ABL1 [cytosol]
(R-HSA-9865161)
0.558
2
UniProt:P38936 CDKN1A
5
p-S130-CDKN1A [nucleoplasm]
(R-HSA-187857)
CDKN1A [nucleoplasm]
(R-HSA-182585)
CDKN1A [cytosol]
(R-HSA-182512)
p-Y77-CDKN1A [cytosol]
(R-HSA-8942601)
p-T145-CDKN1A [cytosol]
(R-HSA-198614)
0.556
3
UniProt:Q71SY5 MED25
1
MED25 [nucleoplasm]
(R-HSA-212414)
0.556
3
UniProt:Q09028 RBBP4
1
RBBP4 [nucleoplasm]
(R-HSA-212223)
0.556
3
UniProt:O75604 USP2
2
USP2 [cytosol]
(R-HSA-5212661)
USP2 [nucleoplasm]
(R-HSA-5689946)
0.556
3
UniProt:P42229 STAT5A
4
STAT5A [cytosol]
(R-HSA-380747)
p-Y694-STAT5A [cytosol]
(R-HSA-507936)
p-Y694-STAT5A [nucleoplasm]
(R-HSA-507995)
STAT5A [nucleoplasm]
(R-HSA-9701901)
0.527
3
UniProt:P19320 VCAM1
1
VCAM1 [plasma membrane]
(R-HSA-197834)
0.527
4
UniProt:Q9UGK3 STAP2
2
STAP2 [cytosol]
(R-HSA-8848028)
p-Y250-STAP2 [plasma membrane]
(R-HSA-8848079)
0.524
10
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