p62 binds ubiquitinated mitochondrial substrates

Stable Identifier
R-HSA-5205673
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
p62 binds ubiquitinated mitochondrial substrates
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
After the ubiquitination events, p62 is recruited to mitochondria, binding the Parkin-ubiquitinated substrates.
Literature References
PubMed ID Title Journal Year
20712405 Autophagosome formation and molecular mechanism of autophagy

Tanida, I

Antioxid. Redox Signal. 2011
Participants
Input
Output
Participates
as an event of
Orthologous Events
p62 binds ubiquitinated mitochondrial substrates (Bos taurus)
p62 binds ubiquitinated mitochondrial substrates (Caenorhabditis elegans)
p62 binds ubiquitinated mitochondrial substrates (Canis familiaris)
p62 binds ubiquitinated mitochondrial substrates (Drosophila melanogaster)
p62 binds ubiquitinated mitochondrial substrates (Gallus gallus)
p62 binds ubiquitinated mitochondrial substrates (Mus musculus)
p62 binds ubiquitinated mitochondrial substrates (Rattus norvegicus)
p62 binds ubiquitinated mitochondrial substrates (Sus scrofa)
Authored
Gillespie, ME  (2013-11-21)
Reviewed
Chauss, D  (2015-09-01)
Kantorow, M  (2015-09-01)
Created
Gillespie, ME  (2013-12-05)
Cite Us!