Reactome | MAP1LC3A [cytosol]

MAP1LC3A [cytosol]

Stable Identifier

R-HSA-5205676

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

LC3A-I, Microtubule-associated proteins 1A/1B light chain 3A, MLP3A_HUMAN

Icon

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9H492 MAP1LC3A

Gene Names

MAP1LC3A

Chain

chain:1-120, propeptide:-

Reference Genes

BioGPS Gene:84557 MAP1LC3A

COSMIC (genes):MAP1LC3A MAP1LC3A

CTD Gene:84557 MAP1LC3A

dbSNP Gene:84557 MAP1LC3A

ENSEMBL:ENSG00000101460 MAP1LC3A

ENSEMBL_homo_sapiens_GENE:ENSG00000101460.13 MAP1LC3A

HGNC:6838 MAP1LC3A

KEGG Gene (Homo sapiens):84557 MAP1LC3A

Monarch:84557 MAP1LC3A

NCBI Gene:84557 MAP1LC3A

OMIM:601242 MAP1LC3A

UCSC:Q9H492 MAP1LC3A

Reference Transcript

Other Identifiers

11721701_a_at

16912954

224378_PM_x_at

224378_x_at

227219_3p_x_at

227219_PM_x_at

227219_x_at

232011_3p_s_at

232011_PM_s_at

232011_s_at

3882985

3882986

3882987

3882991

3882992

3882994

3882995

3882998

3882999

3883000

44906_at

52300_f_at

52302_f_at

59975_at

8062023

84557

A_14_P121568

A_14_P128074

A_23_P154786

A_33_P3300308

GE62249

GO:0000045

GO:0000421

GO:0000422

GO:0005515

GO:0005543

GO:0005737

GO:0005764

GO:0005768

GO:0005770

GO:0005773

GO:0005776

GO:0005829

GO:0005856

GO:0005874

GO:0006914

GO:0006995

GO:0007005

GO:0007254

GO:0008017

GO:0008092

GO:0008289

GO:0009267

GO:0010040

GO:0010288

GO:0012505

GO:0016020

GO:0016236

GO:0023052

GO:0031090

GO:0031410

GO:0031625

GO:0031667

GO:0034198

GO:0038066

GO:0043226

GO:0043231

GO:0044754

GO:0045202

GO:0060395

GO:0070301

GO:0071280

GO:0090650

GO:0097352

GO:0098978

HMNXSV003001074

Hs.134707.0.S1_3p_s_at

Hs.134707.1.S1_3p_s_at

ILMN_1711986

ILMN_1772958

ILMN_1776188

PH_hs_0019488

PH_hs_0033200

TC20000243.hg

g13625770_3p_s_at

Participates

as a member of

Other forms of this molecule

MAP1LC3A [autophagosome membrane]

MAP1LC3A(1-121) [cytosol]

Inferred To

Homologues of MAP1LC3A [cytosol] (Dictyostelium discoideum)

Map1lc3a [cytosol] (Mus musculus)

Map1lc3a [cytosol] (Rattus norvegicus)

MAP1LC3A [cytosol] (Bos taurus)

MAP1LC3A [cytosol] (Dictyostelium discoideum)

MAP1LC3A [cytosol] (Gallus gallus)

MAP1LC3A [cytosol] (Plasmodium falciparum)

MAP1LC3A [cytosol] (Sus scrofa)

atg8 [cytosol] (Dictyostelium discoideum)

atg8 [cytosol] (Schizosaccharomyces pombe)

ATG8 [cytosol] (Saccharomyces cerevisiae)

map1lc3a [cytosol] (Danio rerio)

map1lc3a [cytosol] (Xenopus tropicalis)

lgg-2 [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

NP_115903.1, NP_852610.1

OpenTargets

ENSG00000101460

HPA

ENSG00000101460-MAP1LC3A

GeneCards

Q9H492

Ensembl

ENSP00000380821, ENSP00000353886, ENST00000374837, ENSP00000363970, ENST00000360668, ENST00000397709, ENSG00000101460

PRO

Q9H492

Pharos - Targets

Q9H492

PDB

7R9Z, 8T2L, 5CX3, 3WAN, 5DPR, 4ZDV, 7R9W, 3ECI, 6TBE, 3WAL, 7RA0

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13501 SQSTM1	7	SQSTM1(2-251)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711967) SQSTM1(2-251)-ALK(1058-1620) fusion [cytosol] (R-HSA-9711954) K7 ub-SQSTM1 [cytosol] (R-HSA-9759088) p-S349 SQSTM1 [cytosol] (R-HSA-9766524) ub K420 p-S349 SQSTM1 [cytosol] (R-HSA-9766536) SQSTM1 [nucleoplasm] (R-HSA-210961) SQSTM1 [cytosol] (R-HSA-193937)	0.951	16
UniProt:Q14596 NBR1	2	NBR1 [peroxisomal membrane] (R-HSA-9665177) NBR1 [cytosol] (R-HSA-9665180)	0.684	5
UniProt:Q8IVP5 FUNDC1	4	p-S17-FUNDC1 [mitochondrial outer membrane] (R-HSA-8948140) p-S13,Y18-FUNDC1 [mitochondrial outer membrane] (R-HSA-8934915) FUNDC1 [mitochondrial outer membrane] (R-HSA-8934922) p-S13-FUNDC1 [mitochondrial outer membrane] (R-HSA-8934910)	0.666	4
UniProt:Q9Z2F7	1	Bnip3l [mitochondrial outer membrane] (R-MMU-6798001)	0.65	7
UniProt:Q9UHD2 TBK1	5	pS-172,K48polyUb-TBK1 [cytosol] (R-HSA-3249397) p-TBK1 [cytosol] (R-HSA-9008705) K63polyUb-K30,K401-TBK1 [cytosol] (R-HSA-9730430) TBK1 [cytosol] (R-HSA-166267) p-S172-TBK1 [cytosol] (R-HSA-168379)	0.544	2
UniProt:Q9H0E2 TOLLIP	4	TOLLIP [cytosol] (R-HSA-446885) TOLLIP [azurophil granule lumen] (R-HSA-6799709) TOLLIP [extracellular region] (R-HSA-6800448) TOLLIP [specific granule lumen] (R-HSA-6799719)	0.463	3

Cite Us!