Reactome | COPRS [nucleoplasm]

COPRS [nucleoplasm]

Stable Identifier

R-HSA-5212681

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Coordinator of PRMT5 and differentiation stimulator, COPRS_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q9NY12 GAR1

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External Reference Information

External Reference

UniProt:Q9NQ92 COPRS

Gene Names

COPRS, C17orf79, COPR5

Chain

chain:1-184

Reference Genes

BioGPS Gene:55352 COPRS

COSMIC (genes):COPRS COPRS

CTD Gene:55352 COPRS

dbSNP Gene:55352 COPRS

ENSEMBL:ENSG00000172301 COPRS

ENSEMBL_homo_sapiens_GENE:ENSG00000172301.11 COPRS

HGNC:28848 COPRS

KEGG Gene (Homo sapiens):55352 COPRS

Monarch:55352 COPRS

NCBI Gene:55352 COPRS

UCSC:Q9NQ92 COPRS

Reference Transcript

RefSeq:NM_018405.3 COPRS

Other Identifiers

11727453_a_at

16843179

225096_PM_at

225096_at

3752425

3752426

3752429

3752430

3752433

3752435

3752436

43462_s_at

46304_at

55352

8014073

A_23_P152858

A_24_P130296

GE55314

GO:0005515

GO:0005634

GO:0005654

GO:0005829

GO:0005886

GO:0006325

GO:0006338

GO:0007517

GO:0036211

GO:0042393

GO:0043226

GO:0043985

GO:0048856

HMNXSV003046029

Hs.8179.0.S1_3p_at

ILMN_1752947

PH_hs_0000876

PH_hs_0030963

TC17001345.hg

Participates

as an input of

COPRS binds CCND1:CDK4:PRMT5:pT5-WDR77 (Homo sapiens)

as a component of

CCND1:CDK4:PRMT5:pT5-WDR77:COPRS [nucleoplasm] (Homo sapiens)

Inferred To

Ghost homologue of COPRS [nucleoplasm] (Danio rerio)

Ghost homologue of COPRS [nucleoplasm] (Drosophila melanogaster)

Ghost homologue of COPRS [nucleoplasm] (Xenopus tropicalis)

COPRS [nucleoplasm] (Bos taurus)

COPRS [nucleoplasm] (Canis familiaris)

COPRS [nucleoplasm] (Sus scrofa)

Coprs [nucleoplasm] (Mus musculus)

Coprs [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_060875.2

OpenTargets

ENSG00000172301

GeneCards

Q9NQ92

HPA

ENSG00000172301-COPRS

Ensembl

ENSP00000304327, ENSG00000172301, ENST00000302362

PRO

Q9NQ92

Pharos - Targets

Q9NQ92

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O14744 PRMT5	3	p-Y297,304,307-PRMT5 [nucleoplasm] (R-HSA-5211300) PRMT5 [nucleoplasm] (R-HSA-5205609) PRMT5 [cytosol] (R-HSA-191876)	0.706	7
UniProt:P62312 LSM6	2	LSM6 [cytosol] (R-HSA-429936) LSM6 [nucleoplasm] (R-HSA-6806794)	0.527	2
UniProt:P83111 LACTB			0.527	2
UniProt:P14678 SNRPB	4	SNRPB [nucleoplasm] (R-HSA-71896) Me2-R108,R112-SNRPB [nucleoplasm] (R-HSA-192213) SNRPB [cytosol] (R-HSA-191798) 2xMe-SNRPB [cytosol] (R-HSA-192218)	0.527	2
UniProt:Q14011 CIRBP			0.527	2
UniProt:P61313 RPL15	1	RPL15 [cytosol] (R-HSA-72416)	0.527	2
UniProt:P31943 HNRNPH1	1	HNRNPH1 [nucleoplasm] (R-HSA-71941)	0.527	2
UniProt:O95785 WIZ			0.527	2
UniProt:P63162 SNRPN	1	Me2-R108,R112-SNRPN [nucleoplasm] (R-HSA-8865931)	0.527	2
UniProt:P22087 FBL	1	FBL [nucleoplasm] (R-HSA-6790638)	0.527	2
UniProt:P54105 CLNS1A	1	CLNS1A [cytosol] (R-HSA-191796)	0.527	2
UniProt:P61758 VBP1	1	VBP1 [cytosol] (R-HSA-379543)	0.527	3
UniProt:Q9BRS2 RIOK1	2	RIOK1 [nucleoplasm] (R-HSA-5226890) RIOK1 [cytosol] (R-HSA-6791525)	0.527	2
UniProt:Q9NY12 GAR1	1	GAR1 [nucleoplasm] (R-HSA-6790707)	0.527	3
UniProt:P15880 RPS2	3	RPS2 [nucleoplasm] (R-HSA-6790655) Me2aR-RPS2 [cytosol] (R-HSA-8879138) RPS2 [cytosol] (R-HSA-72347)	0.527	2
UniProt:P62805 H4C1	17	polySUMO3-HIST1H4 [nucleoplasm] (R-HSA-4570531) monoSUMO1-HIST1H4 [nucleoplasm] (R-HSA-4570518) 4xAcK-HIST1H4A [nucleoplasm] (R-HSA-427390) AcK5,12-HIST1H4A [nucleoplasm] (R-HSA-212078) AcK13-HIST1H4 [nucleoplasm] (R-HSA-4568744) Me2aR4-HIST1H4 [nucleoplasm] (R-HSA-5229015) Me2sR4-HIST1H4 [nucleoplasm] (R-HSA-4754243) MeR4-HIST1H4 [nucleoplasm] (R-HSA-4754240) Me3K21-HIST1H4 [nucleoplasm] (R-HSA-5651656) HIST1H4A [extracellular region] (R-HSA-977569) AcK17-HIST1H4 [nucleoplasm] (R-HSA-427469) AcK6-HIST1H4 [nucleoplasm] (R-HSA-4568748) AcK9-HIST1H4 [nucleoplasm] (R-HSA-4568758) MeK21-HIST1H4 [nucleoplasm] (R-HSA-5423110) AcK-HIST1H4 [nucleoplasm] (R-HSA-3451124) Me2K21-HIST1H4 [nucleoplasm] (R-HSA-5651652) HIST1H4 [nucleoplasm] (R-HSA-181902)	0.525	3

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