Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
SLC38A9 [lysosomal membrane]
Stable Identifier
R-HSA-5215938
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal membrane
Synonyms
Putative sodium-coupled neutral amino acid transporter 9, S38A9_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Autophagy (Homo sapiens)
Macroautophagy (Homo sapiens)
Active MTORC1 binds the ULK1 complex (Homo sapiens)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
Active MTORC1 phosphorylates ULK1 (Homo sapiens)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
MTORC1 dissociates from ULK complex (Homo sapiens)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
MTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
MTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
Rheb in the MTORC1 complex hydrolyses GTP (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Homo sapiens)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
MTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to starvation (Homo sapiens)
Amino acids regulate mTORC1 (Homo sapiens)
RRAGA,B exchanges GDP for GTP (Homo sapiens)
SLC38A9:L-Arg [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Homo sapiens)
SLC38A9:L-Arg [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Homo sapiens)
SLC38A9:L-Arg [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Homo sapiens)
SLC38A9:L-Arg [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Homo sapiens)
SLC38A9:L-Arg [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Homo sapiens)
SLC38A9:L-Arg [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Homo sapiens)
SLC38A9:L-Arg [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Metabolic Genes (Homo sapiens)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
PIP3 activates AKT signaling (Homo sapiens)
PTEN Regulation (Homo sapiens)
Regulation of PTEN gene transcription (Homo sapiens)
MAF1 translocates to the nucleus (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 phosphorylates MAF1 (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
MTOR signalling (Homo sapiens)
AKT1S1 (PRAS40) binds mTORC1 (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Homo sapiens)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
Energy dependent regulation of mTOR by LKB1-AMPK (Homo sapiens)
AMPK phosphorylates Raptor in the mTORC1 complex (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
Formation of active mTORC1 complex (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 binds Ragulator:Rag dimers (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 phosphorylates AKT1S1 (Homo sapiens)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1-mediated signalling (Homo sapiens)
Phosphorylation of 4E-BP1 by activated mTORC1 (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
SLC38A9 [lysosomal membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8NBW4 SLC38A9
Gene Names
SLC38A9, URLC11
Chain
chain:1-561
Reference Genes
BioGPS Gene:153129 SLC38A9
COSMIC (genes):SLC38A9 SLC38A9
CTD Gene:153129 SLC38A9
dbSNP Gene:153129 SLC38A9
ENSEMBL:ENSG00000177058 SLC38A9
HGNC:26907 SLC38A9
KEGG:hsa:153129 SLC38A9
Monarch:153129 SLC38A9
NCBI Gene:153129 SLC38A9
OMIM:616203 SLC38A9
UCSC:Q8NBW4 SLC38A9
Reference Transcript
RefSeq:XM_006714537.2 SLC38A9
RefSeq:XM_006714538.3 SLC38A9
RefSeq:XM_006714539.3 SLC38A9
RefSeq:XM_011543173.1 SLC38A9
RefSeq:NM_001258286.1 SLC38A9
RefSeq:NM_001258287.1 SLC38A9
RefSeq:XM_011543174.1 SLC38A9
RefSeq:NM_173514.3 SLC38A9
Other Identifiers
11730324_s_at
11755940_a_at
11756786_x_at
153129
235241_PM_at
235241_at
242330_PM_at
242330_at
243709_PM_at
243709_at
2591162
2744476
2857309
2857310
2857311
2857312
2857313
2857315
2857318
2857319
2857320
2857321
2857322
2857323
2857326
2857327
2857328
2857329
2857330
2857331
2857332
2857333
2857334
2857335
2857336
2857338
2857339
2857340
2857341
2857342
2857343
2857344
2857345
2857346
2857353
2857354
2857355
2857356
2857357
2857358
2857359
2857360
2857361
2857362
2857363
2857364
2857365
2857374
53691_at
74325_at
76235_at
8112121
A_32_P126311
GE525488
GO:0003333
GO:0005085
GO:0005215
GO:0005515
GO:0005764
GO:0005765
GO:0005768
GO:0005770
GO:0005773
GO:0006865
GO:0006867
GO:0006868
GO:0008289
GO:0015171
GO:0015179
GO:0015182
GO:0015186
GO:0015190
GO:0015485
GO:0015803
GO:0016020
GO:0031410
GO:0031902
GO:0032008
GO:0032935
GO:0034618
GO:0043226
GO:0046872
GO:0055085
GO:0061459
GO:0071230
GO:0071986
GO:0098772
GO:0140299
GO:1903826
GO:1904263
GO:1990877
HMNXSV003039314
Hs.120506.0.A1_3p_at
Hs.55560.0.A1_3p_at
ILMN_1773643
PH_hs_0018453
Participates
as a component of
SLC38A9:L-Arg [lysosomal membrane] (Homo sapiens)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
as an input of
SLC38A9 binds Ragulator:Rag dimers (Homo sapiens)
Inferred To
Ghost homologue of SLC38A9 [lysosomal membrane]
(Dictyostelium discoideum)
Ghost homologue of SLC38A9 [lysosomal membrane]
(Drosophila melanogaster)
Ghost homologue of SLC38A9 [lysosomal membrane]
(Schizosaccharomyces pombe)
SLC38A9 [lysosomal membrane]
(Bos taurus)
SLC38A9 [lysosomal membrane]
(Caenorhabditis elegans)
SLC38A9 [lysosomal membrane]
(Canis familiaris)
SLC38A9 [lysosomal membrane]
(Danio rerio)
SLC38A9 [lysosomal membrane]
(Gallus gallus)
SLC38A9 [lysosomal membrane]
(Mus musculus)
SLC38A9 [lysosomal membrane]
(Rattus norvegicus)
SLC38A9 [lysosomal membrane]
(Sus scrofa)
SLC38A9 [lysosomal membrane]
(Xenopus tropicalis)
Cross References
RefSeq
XP_006714601.1
,
XP_006714600.1
,
NP_775785.2
,
XP_011541475.1
,
XP_011541476.1
,
NP_001245216.1
,
XP_006714602.1
,
NP_001245215.1
Guide to Pharmacology - Targets
1177
OpenTargets
ENSG00000177058
ENSEMBL
ENSP00000427335
,
ENSP00000316596
,
ENSP00000420934
,
ENSP00000380074
,
ENST00000318672
,
ENST00000396865
,
ENST00000515629
,
ENST00000512595
HPA
ENSG00000177058-SLC38A9
PRO
Q8NBW4
Pharos - Targets
Q8NBW4
GlyGen
Q8NBW4
PDB
6WJ2
,
8DHB
,
6WJ3
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q7L523 RRAGA
2
RRAGA [cytosol]
(R-HSA-5653577)
K63polyUb-K142,K220,K230,K244-RRAGA [cytosol]
(R-HSA-8938830)
0.829
17
UniProt:Q6IAA8 LAMTOR1
5
LAMTOR1 [lysosomal membrane]
(R-HSA-5653582)
LAMTOR1 [ficolin-1-rich granule membrane]
(R-HSA-6801003)
LAMTOR1 [plasma membrane]
(R-HSA-6806270)
LAMTOR1 [azurophil granule membrane]
(R-HSA-6799633)
LAMTOR1 [specific granule membrane]
(R-HSA-6799631)
0.767
15
UniProt:O43504 LAMTOR5
1
LAMTOR5 [lysosomal membrane]
(R-HSA-5655441)
0.723
6
UniProt:Q0VGL1 LAMTOR4
1
LAMTOR4 [lysosomal membrane]
(R-HSA-5655432)
0.723
6
UniProt:Q9Y2Q5 LAMTOR2
5
LAMTOR2 [lysosomal membrane]
(R-HSA-5653583)
LAMTOR2 [endosome membrane]
(R-HSA-5693293)
LAMTOR2 [specific granule membrane]
(R-HSA-6800168)
LAMTOR2 [plasma membrane]
(R-HSA-6806286)
LAMTOR2 [tertiary granule membrane]
(R-HSA-6800165)
0.669
5
UniProt:Q9HB90 RRAGC
1
RRAGC [cytosol]
(R-HSA-5653949)
0.662
9
UniProt:Q9UHA4 LAMTOR3
5
LAMTOR3 [lysosomal membrane]
(R-HSA-5653581)
LAMTOR3 [endosome membrane]
(R-HSA-5693294)
LAMTOR3 [specific granule membrane]
(R-HSA-6800178)
LAMTOR3 [plasma membrane]
(R-HSA-6806307)
LAMTOR3 [tertiary granule membrane]
(R-HSA-6800189)
0.623
7
UniProt:Q5VZM2 RRAGB
1
RRAGB [cytosol]
(R-HSA-5653579)
0.564
2
UniProt:O14894 T4S5
0.463
4
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text