Reactome | SLC38A9 [lysosomal membrane]

SLC38A9 [lysosomal membrane]

Stable Identifier

R-HSA-5215938

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

lysosomal membrane

Synonyms

Putative sodium-coupled neutral amino acid transporter 9, S38A9_HUMAN

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Locations in the PathwayBrowser for interactor UniProt:Q6IAA8 LAMTOR1

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External Reference Information

External Reference

UniProt:Q8NBW4 SLC38A9

Gene Names

SLC38A9, URLC11

Chain

chain:1-561

Reference Genes

BioGPS Gene:153129 SLC38A9

COSMIC (genes):SLC38A9 SLC38A9

CTD Gene:153129 SLC38A9

dbSNP Gene:153129 SLC38A9

ENSEMBL:ENSG00000177058 SLC38A9

ENSEMBL_homo_sapiens_GENE:ENSG00000177058.12 SLC38A9

HGNC:26907 SLC38A9

KEGG Gene (Homo sapiens):153129 SLC38A9

Monarch:153129 SLC38A9

NCBI Gene:153129 SLC38A9

OMIM:616203 SLC38A9

UCSC:Q8NBW4 SLC38A9

Reference Transcript

Other Identifiers

11730324_s_at

11755940_a_at

11756786_x_at

153129

235241_PM_at

235241_at

2857309

2857310

2857311

2857312

2857313

2857315

2857320

2857321

2857323

2857326

2857327

2857328

2857329

2857330

2857331

2857335

2857340

2857341

2857343

2857344

2857353

2857354

2857358

2857359

2857362

2857363

53691_at

8112121

A_32_P126311

GE525488

GO:0003333

GO:0005085

GO:0005215

GO:0005515

GO:0005764

GO:0005765

GO:0005768

GO:0005770

GO:0005773

GO:0006865

GO:0006867

GO:0006868

GO:0008289

GO:0015171

GO:0015179

GO:0015182

GO:0015186

GO:0015190

GO:0015485

GO:0015803

GO:0016020

GO:0023052

GO:0031410

GO:0031902

GO:0032008

GO:0032935

GO:0034618

GO:0043226

GO:0046872

GO:0055085

GO:0061459

GO:0071230

GO:0071986

GO:0098772

GO:0140299

GO:1903826

GO:1904263

GO:1990877

HMNXSV003039314

Hs.55560.0.A1_3p_at

ILMN_1773643

PH_hs_0018453

Participates

as a component of

as an input of

SLC38A9 binds Ragulator:Rag dimers (Homo sapiens)

Inferred To

Ghost homologue of SLC38A9 [lysosomal membrane] (Dictyostelium discoideum)

Ghost homologue of SLC38A9 [lysosomal membrane] (Drosophila melanogaster)

Ghost homologue of SLC38A9 [lysosomal membrane] (Schizosaccharomyces pombe)

SLC38A9 [lysosomal membrane] (Bos taurus)

SLC38A9 [lysosomal membrane] (Caenorhabditis elegans)

SLC38A9 [lysosomal membrane] (Canis familiaris)

SLC38A9 [lysosomal membrane] (Danio rerio)

SLC38A9 [lysosomal membrane] (Gallus gallus)

SLC38A9 [lysosomal membrane] (Mus musculus)

SLC38A9 [lysosomal membrane] (Rattus norvegicus)

SLC38A9 [lysosomal membrane] (Sus scrofa)

SLC38A9 [lysosomal membrane] (Xenopus tropicalis)

Cross References

RefSeq

XP_011541475.1, NP_001245215.1, XP_006714602.1, NP_775785.2, XP_006714600.1, NP_001245216.1, XP_006714601.1, XP_011541476.1

Guide to Pharmacology - Targets

1177

OpenTargets

ENSG00000177058

GeneCards

Q8NBW4

HPA

ENSG00000177058-SLC38A9

Ensembl

ENST00000396865, ENSP00000316596, ENSP00000420934, ENST00000318672, ENST00000512595, ENSG00000177058, ENSP00000380074, ENSP00000427335, ENST00000515629

PRO

Q8NBW4

Pharos - Targets

Q8NBW4

PDB

6WJ3, 8DHB, 6WJ2

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q7L523 RRAGA	2	K63polyUb-K142,K220,K230,K244-RRAGA [cytosol] (R-HSA-8938830) RRAGA [cytosol] (R-HSA-5653577)	0.829	17
UniProt:Q6IAA8 LAMTOR1	5	LAMTOR1 [specific granule membrane] (R-HSA-6799631) LAMTOR1 [lysosomal membrane] (R-HSA-5653582) LAMTOR1 [ficolin-1-rich granule membrane] (R-HSA-6801003) LAMTOR1 [plasma membrane] (R-HSA-6806270) LAMTOR1 [azurophil granule membrane] (R-HSA-6799633)	0.767	15
UniProt:O43504 LAMTOR5	1	LAMTOR5 [lysosomal membrane] (R-HSA-5655441)	0.723	6
UniProt:Q0VGL1 LAMTOR4	1	LAMTOR4 [lysosomal membrane] (R-HSA-5655432)	0.723	6
UniProt:Q9Y2Q5 LAMTOR2	5	LAMTOR2 [specific granule membrane] (R-HSA-6800168) LAMTOR2 [plasma membrane] (R-HSA-6806286) LAMTOR2 [tertiary granule membrane] (R-HSA-6800165) LAMTOR2 [endosome membrane] (R-HSA-5693293) LAMTOR2 [lysosomal membrane] (R-HSA-5653583)	0.669	5
UniProt:Q9HB90 RRAGC	1	RRAGC [cytosol] (R-HSA-5653949)	0.662	9
UniProt:Q9UHA4 LAMTOR3	5	LAMTOR3 [specific granule membrane] (R-HSA-6800178) LAMTOR3 [plasma membrane] (R-HSA-6806307) LAMTOR3 [tertiary granule membrane] (R-HSA-6800189) LAMTOR3 [endosome membrane] (R-HSA-5693294) LAMTOR3 [lysosomal membrane] (R-HSA-5653581)	0.623	7
UniProt:Q5VZM2 RRAGB	1	RRAGB [cytosol] (R-HSA-5653579)	0.564	2

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