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ATP6AP1 [endosome membrane]
Stable Identifier
R-HSA-5215981
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endosome membrane
Synonyms
V-type proton ATPase subunit S1, VAS1_HUMAN
Locations in the PathwayBrowser for interactor UniProt:O75787%20ATP6AP2
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by Insulin receptor (Homo sapiens)
Insulin receptor recycling (Homo sapiens)
ATP6AP1 binds V-ATPase (Homo sapiens)
ATP6AP1 [endosome membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
ATP6AP1 binds V-ATPase (Homo sapiens)
ATP6AP1 [endosome membrane] (Homo sapiens)
Iron uptake and transport (Homo sapiens)
Transferrin endocytosis and recycling (Homo sapiens)
ATP6AP1 binds V-ATPase (Homo sapiens)
ATP6AP1 [endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15904 ATP6AP1
Gene Names
ATP6AP1, ATP6IP1, ATP6S1, VATPS1, XAP3
Chain
signal peptide:1-41, chain:42-470, propeptide:42-231
Reference Genes
BioGPS Gene:537 ATP6AP1
COSMIC (genes):ATP6AP1 ATP6AP1
CTD Gene:537 ATP6AP1
dbSNP Gene:537 ATP6AP1
ENSEMBL:ENSG00000071553 ATP6AP1
ENSEMBL_homo_sapiens_GENE:ENSG00000071553.18 ATP6AP1
HGNC:868 ATP6AP1
Monarch:537 ATP6AP1
NCBI Gene:537 ATP6AP1
OMIM:300197 ATP6AP1
UCSC:Q15904 ATP6AP1
Reference Transcript
RefSeq:NM_001183.5 ATP6AP1
RefSeq:XM_011531179.1 ATP6AP1
Other Identifiers
11749258_a_at
11754958_s_at
17108354
207809_PM_s_at
207809_s_at
35770_at
3996382
3996383
3996384
3996385
3996386
3996388
3996390
3996391
3996392
3996393
3996394
3996395
3996396
3996397
3996398
3996399
3996400
3996401
3996402
3996403
3996405
537
8170882
A_23_P250462
D16469_at
GE79783
GO:0000139
GO:0001671
GO:0005515
GO:0005576
GO:0005615
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006811
GO:0006879
GO:0006886
GO:0007035
GO:0007040
GO:0007042
GO:0010008
GO:0016020
GO:0016192
GO:0016469
GO:0030154
GO:0030641
GO:0030665
GO:0030672
GO:0031267
GO:0031410
GO:0033116
GO:0033176
GO:0036035
GO:0036295
GO:0043226
GO:0045202
GO:0048388
GO:0048856
GO:0051452
GO:0055065
GO:0055085
GO:0061795
GO:0070062
GO:0072659
GO:0097401
GO:0098772
GO:0098793
GO:0099638
GO:1902600
HMNXSV003029783
ILMN_1697694
TC0X000771.hg
TC0X001937.hg
g4557340_3p_s_at
Participates
as an input of
ATP6AP1 binds V-ATPase (Homo sapiens)
as a component of
V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
Other forms of this molecule
ATP6AP1 [endoplasmic reticulum membrane]
Inferred To
Ghost homologue of ATP6AP1 [endosome membrane]
(Danio rerio)
Ghost homologue of ATP6AP1 [endosome membrane]
(Dictyostelium discoideum)
Ghost homologue of ATP6AP1 [endosome membrane]
(Gallus gallus)
Ghost homologue of ATP6AP1 [endosome membrane]
(Plasmodium falciparum)
Ghost homologue of ATP6AP1 [endosome membrane]
(Saccharomyces cerevisiae)
Ghost homologue of ATP6AP1 [endosome membrane]
(Schizosaccharomyces pombe)
VhaAC45 [endosome membrane]
(Drosophila melanogaster)
atp6ap1.2 [endosome membrane]
(Xenopus tropicalis)
vha-19 [endosome membrane]
(Caenorhabditis elegans)
ATP6AP1 [endosome membrane]
(Bos taurus)
ATP6AP1 [endosome membrane]
(Canis familiaris)
ATP6AP1 [endosome membrane]
(Sus scrofa)
Atp6ap1 [endosome membrane]
(Mus musculus)
Atp6ap1 [endosome membrane]
(Rattus norvegicus)
Cross References
RefSeq
XP_011529481.1
,
NP_001174.2
OpenTargets
ENSG00000071553
ZINC - Substances
VAS1_HUMAN
ZINC target
Q15904
ZINC - Biogenic
VAS1_HUMAN
PRO
Q15904
PDB
6WM3
,
7UNF
,
6WM2
,
6WM4
,
6WLW
,
7U4T
GeneCards
Q15904
HPA
ENSG00000071553-ATP6AP1
Ensembl
ENSG00000071553
,
ENST00000369762
,
ENSP00000358777
Pharos - Targets
Q15904
Orphanet
27598
ZINC - Predictions - Purchasable
VAS1_HUMAN
HMDB Protein
HMDBP09536
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P0DTD1-PRO_0000449624 REP
0.832
12
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
UniProt:O75787 ATP6AP2
3
ATP6AP2 [ficolin-1-rich granule membrane]
(R-HSA-6800921)
ATP6AP2 [tertiary granule membrane]
(R-HSA-6799717)
ATP6AP2 [plasma membrane]
(R-HSA-2022356)
0.527
2
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