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SYP [clathrin-sculpted glutamate transport vesicle membrane]
Stable Identifier
R-HSA-5215991
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
clathrin-sculpted glutamate transport vesicle membrane
Synonyms
Synaptophysin, SYPH_HUMAN
Locations in the PathwayBrowser
Expand all
Sensory Perception (Homo sapiens)
Sensory processing of sound (Homo sapiens)
Sensory processing of sound by inner hair cells of the cochlea (Homo sapiens)
Exocytosis of glutamate from cochlear inner hair cell (Homo sapiens)
Glutamate depleted vesicle:Ca2+:SNAP25:STX1A [plasma membrane] (Homo sapiens)
Glutamate depleted synaptic vesicle (cochlear inner hair cell) [cytosol] (Homo sapiens)
SYP [clathrin-sculpted glutamate transport vesicle membrane] (Homo sapiens)
Glutamate loaded vesicle:BSN:RIBEYE:PICCOLINO [cytosol] (Homo sapiens)
Glutamate loaded synaptic vesicle (cochlear inner hair cell) [cytosol] (Homo sapiens)
SYP [clathrin-sculpted glutamate transport vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P08247 SYP
Gene Names
SYP
Chain
chain:1-313
Reference Genes
BioGPS Gene:6855 SYP
COSMIC (genes):SYP SYP
CTD Gene:6855 SYP
dbSNP Gene:6855 SYP
ENSEMBL:ENSG00000102003 SYP
ENSEMBL:ENSG00000102003.12 SYP
HGNC:11506 SYP
KEGG Gene (Homo sapiens):6855 SYP
Monarch:6855 SYP
NCBI Gene:6855 SYP
OMIM:313475 SYP
UCSC:P08247 SYP
Reference Transcript
RefSeq:NM_003179.2 SYP
Other Identifiers
11725033_a_at
11725034_at
11747728_a_at
17110835
213200_PM_at
213200_at
2987645
37182_at
4007900
4007902
4007903
4007904
4007905
4007906
4007908
4007909
4007913
4007917
6855
8172573
A_23_P136936
GE87832
GO:0005515
GO:0005886
GO:0006897
GO:0008021
GO:0008289
GO:0015485
GO:0016020
GO:0016188
GO:0016192
GO:0023052
GO:0030672
GO:0031410
GO:0031594
GO:0042169
GO:0042734
GO:0042802
GO:0043005
GO:0043195
GO:0043226
GO:0044306
GO:0045202
GO:0048168
GO:0048169
GO:0048172
GO:0048471
GO:0048488
GO:0048499
GO:0048786
GO:0060076
GO:0061024
GO:0071310
GO:0098685
GO:0098793
GO:2000300
GO:2000474
HMNXSV003034111
Hs.75667.0.S1_3p_at
ILMN_1701483
PH_hs_0004358
TC0X001029.hg
X06389_at
Participates
as a component of
Glutamate depleted synaptic vesicle (cochlear inner hair cell) [cytosol] (Homo sapiens)
Glutamate loaded synaptic vesicle (cochlear inner hair cell) [cytosol] (Homo sapiens)
Cross References
RefSeq
NP_003170.1
OpenTargets
ENSG00000102003
GeneCards
P08247
HPA
ENSG00000102003-SYP
Ensembl
ENST00000479808
,
ENSG00000102003
,
ENSP00000418169
,
ENSP00000263233
,
ENST00000263233
PRO
P08247
Pharos - Targets
P08247
Orphanet
19024
HMDB Protein
HMDBP08024
Interactors (11)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.666
13
UniProt:Q96T60 PNKP
1
PNKP [nucleoplasm]
(R-HSA-5649651)
0.556
3
UniProt:P05067 APP
20
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-713) [extracellular region]
(R-HSA-879340)
0.556
3
UniProt:Q6IN84 MRM1
1
MRM1 [mitochondrial matrix]
(R-HSA-6793088)
0.556
3
UniProt:P53365 ARFIP2
1
ARFIP2 [cytosol]
(R-HSA-6813848)
0.556
3
UniProt:Q96E11 MRRF
1
MRRF [mitochondrial matrix]
(R-HSA-5419265)
0.556
3
UniProt:O60664 PLIN3
7
p-PLIN3 [lysosomal lumen]
(R-HSA-9639396)
p-PLIN3 [cytosol]
(R-HSA-9613664)
p-PLIN3 [lipid droplet]
(R-HSA-9613539)
PLIN3 [lipid droplet]
(R-HSA-9613337)
p-PLIN3 [late endosome lumen]
(R-HSA-9639393)
PLIN3 [cytosol]
(R-HSA-6814628)
PLIN3 [transport vesicle]
(R-HSA-6813900)
0.556
3
UniProt:O95971 CD160
1
CD160 [plasma membrane]
(R-HSA-198014)
0.556
3
UniProt:O95363 FARS2
1
FARS2(1-?) [mitochondrial matrix]
(R-HSA-379565)
0.556
3
UniProt:Q9NR28 DIABLO
2
DIABLO [mitochondrial intermembrane space]
(R-HSA-64637)
DIABLO [cytosol]
(R-HSA-114298)
0.556
3
UniProt:Q96E29 MTERF3
2
K48polyUb-MTERFD1 [mitochondrial outer membrane]
(R-HSA-5205630)
MTERFD1 [mitochondrial outer membrane]
(R-HSA-5205688)
0.556
3
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