Reactome | RANGRF [cytosol]

RANGRF [cytosol]

Stable Identifier

R-HSA-5216063

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ran guanine nucleotide release factor, MOG1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9HD47 RANGRF

Gene Names

RANGRF, MOG1, RANGNRF, HSPC165, HSPC236, MDS5

Chain

chain:1-186

Reference Genes

BioGPS Gene:29098 RANGRF

COSMIC (genes):RANGRF RANGRF

CTD Gene:29098 RANGRF

dbSNP Gene:29098 RANGRF

ENSEMBL:ENSG00000108961 RANGRF

HGNC:17679 RANGRF

KEGG:hsa:29098 RANGRF

Monarch:29098 RANGRF

NCBI Gene:29098 RANGRF

OMIM:607954 RANGRF

UCSC:Q9HD47 RANGRF

Reference Transcript

This entity regulates

Positively

SCNAs:SNCBs transport Na+ from extracellular region to cytosol (Homo sapiens)

Inferred To

RANGRF [cytosol] (Bos taurus)

Cross References

ENSEMBL

ENSP00000413190, ENST00000580434, ENST00000439238, ENSP00000462310, ENST00000226105, ENSP00000383940, ENSG00000108961, ENSP00000226105, ENST00000407006

OpenTargets

ENSG00000108961

GeneCards

RANGRF

HPA

ENSG00000108961-RANGRF

PRO

Q9HD47

Pharos - Targets

Q9HD47

Orphanet

RANGRF

HMDB Protein

HMDBP08483

PDB

5YFG

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P62826 RAN	2	RAN [cytosol] (R-HSA-165540) RAN [nucleoplasm] (R-HSA-165528)	0.643	4
UniProt:Q14584 ZNF266	1	ZNF266 [nucleoplasm] (R-HSA-1027391)	0.589	2
UniProt:O95976 IGSF6			0.527	2
UniProt:Q15771 RAB30	3	RAB30 [Golgi membrane] (R-HSA-8849598) GGC-RAB30 [cytosol] (R-HSA-8873972) RAB30 [cytosol] (R-HSA-8873677)	0.527	2
UniProt:Q8WW01 TSEN15	1	TSEN15 [nucleoplasm] (R-HSA-5696772)	0.527	2
UniProt:P20336 RAB3A	9	RAB3A [clathrin-sculpted monoamine transport vesicle membrane] (R-HSA-372512) RAB3A [plasma membrane] (R-HSA-210461) RAB3A [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-917743) RAB3A [clathrin-sculpted glutamate transport vesicle membrane] (R-HSA-210466) RAB3A [clathrin-sculpted acetylcholine transport vesicle membrane] (R-HSA-379365) RAB3A [secretory granule membrane] (R-HSA-6804968) RAB3A [cytosol] (R-HSA-8870410) GGC-RAB3A [cytosol] (R-HSA-8870429) GGC-RAB3A [secretory granule membrane] (R-HSA-8875319)	0.527	3
UniProt:Q6PJI9 WDR59	1	WDR59 [lysosomal membrane] (R-HSA-9638236)	0.527	2
UniProt:Q8IYG6 LRC56			0.527	3
UniProt:Q8N307 MUC20	19	MUC20 [plasma membrane] (R-HSA-8851833) GalNAc-MUC20 [plasma membrane] (R-HSA-8858516) Core 2 (MUC20) [Golgi lumen] (R-HSA-1462330) Core 2a (MUC20) [Golgi lumen] (R-HSA-6784267) GalNAc-MUC20 [Golgi lumen] (R-HSA-1463443) Sialyl Tn antigen (MUC20) [Golgi lumen] (R-HSA-1463558) T-antigen (MUC20) [Golgi lumen] (R-HSA-1462188) Sialyl-2,3 T-antigen (MUC20) [Golgi lumen] (R-HSA-1463479) Sialyl T-antigen (MUC20) [Golgi lumen] (R-HSA-1463469) Disialyl T-antigen (MUC20) [Golgi lumen] (R-HSA-1463482) MUC20 [Golgi lumen] (R-HSA-913634) Core 6 (MUC20) [Golgi lumen] (R-HSA-1462247) extended Core 6 (MUC20) [Golgi lumen] (R-HSA-1967016) Core 7 (MUC20) [Golgi lumen] (R-HSA-1462236) Core 3 (MUC20) [Golgi lumen] (R-HSA-1462344) Core 4 (MUC20) [Golgi lumen] (R-HSA-1462266) Core 5 (MUC20) [Golgi lumen] (R-HSA-1462128) Core 2S (MUC20) [Golgi lumen] (R-HSA-6786382) Core 8 (MUC20) [Golgi lumen] (R-HSA-1462329)	0.527	2
UniProt:Q01130 SRSF2	1	SRSF2 [nucleoplasm] (R-HSA-72033)	0.499	2

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