Reactome | APOD [extracellular region]

APOD [extracellular region]

Stable Identifier

R-HSA-5216199

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Apolipoprotein D, APOD_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P48051 KCNJ6

Expand all

External Reference Information

External Reference

UniProt:P05090 APOD

Gene Names

APOD

Chain

signal peptide:1-20, chain:21-189

Reference Genes

BioGPS Gene:347 APOD

COSMIC (genes):APOD APOD

CTD Gene:347 APOD

dbSNP Gene:347 APOD

ENSEMBL:ENSG00000189058 APOD

HGNC:612 APOD

KEGG:hsa:347 APOD

Monarch:347 APOD

NCBI Gene:347 APOD

OMIM:107740 APOD

UCSC:P05090 APOD

Reference Transcript

RefSeq:NM_001647.3 APOD

Other Identifiers

11717295_s_at

11756065_x_at

11761214_at

16963113

201525_PM_at

201525_at

347

36681_at

4054208

4054209

4054210

4054211

4054213

4054214

4054216

4054217

4054218

4054219

4054228

8092970

A_23_P136777

GE79130

GO:0000302

GO:0001525

GO:0005215

GO:0005319

GO:0005515

GO:0005576

GO:0005615

GO:0005737

GO:0005783

GO:0005840

GO:0005975

GO:0006006

GO:0006629

GO:0006869

GO:0006950

GO:0007420

GO:0008289

GO:0010642

GO:0014012

GO:0015485

GO:0022626

GO:0030425

GO:0042246

GO:0042308

GO:0043025

GO:0043226

GO:0048471

GO:0048662

GO:0048678

GO:0048856

GO:0051895

GO:0060588

GO:0070062

GO:0071638

GO:1900016

GO:2000098

GO:2000405

HMNXSV003011834

ILMN_1780170

J02611_at

TC03002146.hg

g4502162_3p_at

Participates

as an output of

Expression of APOD regulated by NR1H2 or NR1H3 (Homo sapiens)

as a component of

APOD dimer [extracellular region] (Homo sapiens)

Inferred To

CG16933 [extracellular region] (Drosophila melanogaster)

ApoD [extracellular region] (Gallus gallus)

Apod [extracellular region] (Mus musculus)

Apod [extracellular region] (Rattus norvegicus)

APOD [extracellular region] (Bos taurus)

APOD [extracellular region] (Canis familiaris)

APOD [extracellular region] (Sus scrofa)

apodb [extracellular region] (Danio rerio)

Cross References

OpenTargets

ENSG00000189058

ENSEMBL

ENST00000343267, ENSP00000345179

HPA

ENSG00000189058-APOD

PRO

P05090

Pharos - Targets

P05090

GlyGen

P05090

HMDB Protein

HMDBP12684

PDB

2HZQ, 2HZR

Interactors (59)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9P0L0 VAPA	4	VAPA [azurophil granule membrane] (R-HSA-6799364) VAPA [plasma membrane] (R-HSA-6806269) VAPA [endoplasmic reticulum membrane] (R-HSA-429677) VAPA [cytosol] (R-HSA-9609920)	0.718	6
UniProt:O43889-2 CREB3			0.666	4
UniProt:P56270 MAZ			0.589	2
UniProt:Q96A29 SLC35C1	5	SLC35C1 E31* [Golgi membrane] (R-HSA-5653593) SLC35C1 T308* [Golgi membrane] (R-HSA-5653594) SLC35C1 R147C [Golgi membrane] (R-HSA-5653602) SLC35C1 F168del [Golgi membrane] (R-HSA-5653621) SLC35C1 [Golgi membrane] (R-HSA-742352)	0.589	2
UniProt:P43628 KIR2DL3	1	KIR2DL3 [plasma membrane] (R-HSA-3006532)	0.556	3
UniProt:Q99437 ATP6V0B	3	ATP6V0B [endosome membrane] (R-HSA-912584) ATP6V0B [phagocytic vesicle membrane] (R-HSA-1222695) ATP6V0B [lysosomal membrane] (R-HSA-9640187)	0.556	3
UniProt:P11912 CD79A	2	p-Y188,Y199-CD79A [plasma membrane] (R-HSA-983539) CD79A [plasma membrane] (R-HSA-197154)	0.556	3
UniProt:P48165 GJA8	1	GJA8 [endoplasmic reticulum membrane] (R-HSA-190702)	0.556	3
UniProt:A8KA83 A8KA83			0.556	3
UniProt:O15342 ATP6V0E1	3	ATP6V0E1 [endosome membrane] (R-HSA-912582) ATP6V0E1 [phagocytic vesicle membrane] (R-HSA-1222533) ATP6V0E1 [lysosomal membrane] (R-HSA-9640180)	0.556	3
UniProt:Q9H2K0 MTIF3	1	MTIF3 [mitochondrial matrix] (R-HSA-5368284)	0.556	3
UniProt:O15552 FFAR2	1	FFAR2 [plasma membrane] (R-HSA-443944)	0.556	3
UniProt:Q96BA8 CREB3L1	7	CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.556	3
UniProt:P25090 FPR2	4	FPR2 [plasma membrane] (R-HSA-416408) FPR2 [ficolin-1-rich granule membrane] (R-HSA-6803335) FPR2 [specific granule membrane] (R-HSA-6803319) FPR2 [tertiary granule membrane] (R-HSA-6803296)	0.556	3
UniProt:Q3KNW5 SLC10A6	1	SLC10A6 [plasma membrane] (R-HSA-433091)	0.556	3
UniProt:Q8IUN9 CLEC10A	1	CLEC10A [plasma membrane] (R-HSA-1472863)	0.556	3
UniProt:Q13323 BIK			0.556	3
UniProt:Q9BSE2 TMM79			0.556	3
UniProt:Q9BXK5 B2L13			0.556	3
UniProt:Q7Z7G2 CPLX4			0.556	3
UniProt:Q96Q45-2 TMEM237			0.556	5
UniProt:Q5T7V8 GORAB			0.556	3
UniProt:O95471 CLDN7	2	CLDN7 [plasma membrane] (R-HSA-420004) CLDN7 [cell junction] (R-HSA-421241)	0.556	3
UniProt:Q8TED1 GPX8	1	GPX8 [endoplasmic reticulum lumen] (R-HSA-3341303)	0.556	3
UniProt:Q9Y282 ERGI3			0.556	3
UniProt:Q9NQQ7-3 Q9NQQ73			0.556	3
UniProt:O15529 GPR42			0.556	3
UniProt:Q96B21 TM45B			0.556	3
UniProt:Q13113 PDZ1I			0.556	3
UniProt:Q8TDV0 GP151			0.556	3
UniProt:O43315 AQP9	1	AQP9 [plasma membrane] (R-HSA-431761)	0.556	3
UniProt:Q9GZY8-5 MFF			0.556	3
IntAct:EBI-22326698 CCSB ORF ID			0.556	3
UniProt:Q8N6K0 TEX29			0.556	3
UniProt:Q9NVV5-2 AIG1			0.556	3
UniProt:Q49AM1 MTEF2			0.556	3
UniProt:P19397 CD53	3	CD53 [tertiary granule membrane] (R-HSA-6804799) CD53 [plasma membrane] (R-HSA-6804817) CD53 [specific granule membrane] (R-HSA-6804793)	0.556	3
UniProt:Q5JX71 F209A			0.556	3
UniProt:O14880 MGST3	1	MGST3 [endoplasmic reticulum membrane] (R-HSA-176053)	0.556	3
UniProt:P34910-2 P349102			0.556	3
UniProt:O75783 RHBL1			0.556	3
UniProt:Q96BI3 APH1A	2	APH1A [plasma membrane] (R-HSA-3211581) APH1A [endosome membrane] (R-HSA-9010105)	0.556	3
UniProt:Q4KMG9 TM52B			0.556	3
UniProt:P48051 KCNJ6	1	KCNJ6 [plasma membrane] (R-HSA-975242)	0.556	3
UniProt:Q6IBW4-4 NCAPH2			0.556	3
UniProt:Q9Y680 FKBP7			0.556	3
UniProt:Q8N7X8 SIGL1			0.556	3
UniProt:Q8TB36 GDAP1	2	GDAP1 [peroxisomal membrane] (R-HSA-9603788) GDAP1 [cytosol] (R-HSA-9603796)	0.556	3
UniProt:Q9H7M9 VISTA			0.556	3
UniProt:Q15915 ZIC1	1	ZIC1 [nucleoplasm] (R-HSA-9731648)	0.527	2
UniProt:O14656 TOR1A	1	TOR1A [cytosol] (R-HSA-8862858)	0.527	2
UniProt:Q5GAN3 RNS13			0.527	2
UniProt:O95498 VNN2	3	cleaved GPI-VNN2 [extracellular region] (R-HSA-8941027) GPI-VNN2 [plasma membrane] (R-HSA-8940753) VNN2 [plasma membrane] (R-HSA-2980905)	0.527	2
UniProt:O15063 GARRE1	1	KIAA0355 [cytosol] (R-HSA-9691200)	0.527	2
UniProt:Q6P158 DHX57			0.527	2
UniProt:O00622 CYR61	2	p-CYR61 [endoplasmic reticulum lumen] (R-HSA-8956919) CYR61 [endoplasmic reticulum lumen] (R-HSA-5173201)	0.527	2
UniProt:Q9BV68 RNF126	1	RNF126 [cytosol] (R-HSA-8851642)	0.527	2
UniProt:P46089 GPR3			0.527	2
UniProt:Q7L190 DPPA4	1	DPPA4 [nucleoplasm] (R-HSA-452999)	0.527	2

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