Reactome | RNASEL [mitochondrial matrix]

RNASEL [mitochondrial matrix]

Stable Identifier

R-HSA-5223312

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

2-5A-dependent ribonuclease, RN5A_HUMAN

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External Reference Information

External Reference

UniProt:Q05823 RNASEL

Gene Names

RNASEL, RNS4

Chain

chain:1-741

Reference Genes

BioGPS Gene:6041 RNASEL

COSMIC (genes):RNASEL RNASEL

CTD Gene:6041 RNASEL

dbSNP Gene:6041 RNASEL

ENSEMBL:ENSG00000135828 RNASEL

HGNC:10050 RNASEL

KEGG:hsa:6041 RNASEL

Monarch:6041 RNASEL

NCBI Gene:6041 RNASEL

OMIM:180435 RNASEL

UCSC:Q05823 RNASEL

Reference Transcript

RefSeq:NM_021133.3 RNASEL

Other Identifiers

11734358_a_at

11734359_a_at

16697004

221287_PM_at

221287_at

229285_PM_at

229285_at

2447128

2447129

2447130

2447131

2447132

2447133

2447134

2447135

2447138

2447139

2447141

2447142

2447143

2447144

2447145

2447146

46123_at

6041

7922707

A_23_P390172

GE82590

GE87744

GO:0003723

GO:0003824

GO:0004519

GO:0004521

GO:0004540

GO:0004672

GO:0005515

GO:0005524

GO:0005575

GO:0005737

GO:0005739

GO:0005759

GO:0005829

GO:0006355

GO:0006364

GO:0006396

GO:0006397

GO:0006468

GO:0016071

GO:0016363

GO:0016740

GO:0016787

GO:0019843

GO:0030154

GO:0042802

GO:0043021

GO:0043226

GO:0043488

GO:0045071

GO:0045444

GO:0045944

GO:0046326

GO:0046872

GO:0051607

GO:0098542

GO:0140096

GO:0140098

HMNXSV003057568

Hs.56156.0.A1_3p_at

ILMN_1671281

ILMN_2210601

L10381_at

PH_hs_0024628

TC01003607.hg

g10863928_3p_at

Participates

as a component of

RNASEL dimer [mitochondrial matrix] (Homo sapiens)

Other forms of this molecule

RNASEL [cytosol]

Inferred To

asb18 [mitochondrial matrix] (Xenopus tropicalis)

Rnasel [mitochondrial matrix] (Mus musculus)

Rnasel [mitochondrial matrix] (Rattus norvegicus)

RNASEL [mitochondrial matrix] (Bos taurus)

RNASEL [mitochondrial matrix] (Canis familiaris)

RNASEL [mitochondrial matrix] (Gallus gallus)

RNASEL [mitochondrial matrix] (Sus scrofa)

Cross References

RefSeq

NP_066956.1

ENSEMBL

ENSP00000356530, ENST00000539397, ENST00000367559, ENSP00000440844

OpenTargets

ENSG00000135828

ZINC - Substances

RN5A_HUMAN

ZINC target

Q05823

PRO

Q05823

GlyGen

Q05823

PDB

1WDY, 4OAU, 4OAV, 4G8K, 4G8L

HPA

ENSG00000135828-RNASEL

Pharos - Targets

Q05823

Orphanet

RNASEL

ZINC - Predictions - Purchasable

RN5A_HUMAN

HMDB Protein

HMDBP08807

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NWT6 HIF1AN	1	HIF1AN [cytosol] (R-HSA-1234154)	0.837	8
UniProt:Q92187 ST8SIA4	1	ST8SIA4 [Golgi membrane] (R-HSA-422390)	0.527	2
UniProt:Q99677 LPAR4	1	LPAR4 [plasma membrane] (R-HSA-418020)	0.527	2
UniProt:P08247 SYP	1	SYP [clathrin-sculpted glutamate transport vesicle membrane] (R-HSA-5215991)	0.527	2
UniProt:Q14627 IL13RA2	1	IL13RA2 [extracellular region] (R-HSA-449666)	0.527	2
UniProt:P46940 IQGAP1	3	IQGAP1 [cytosol] (R-HSA-5626371) IQGAP1 [secretory granule membrane] (R-HSA-6804803) IQGAP1 [plasma membrane] (R-HSA-381681)	0.499	2

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