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SMARCD2 [nucleoplasm]
Stable Identifier
R-HSA-5225626
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2, SMRD2_HUMAN
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
RMTs methylate histone arginines (Homo sapiens)
CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Homo sapiens)
SWI/SNF chromatin remodelling complex:PRMT5:pT5-WDR77 [nucleoplasm] (Homo sapiens)
SWI/SNF chromatin remodelling complex [nucleoplasm] (Homo sapiens)
SWI/SNF additional components [nucleoplasm] (Homo sapiens)
SMARCD2 [nucleoplasm] (Homo sapiens)
COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Homo sapiens)
SWI/SNF chromatin remodelling complex:PRMT5:pT5-WDR77 [nucleoplasm] (Homo sapiens)
SWI/SNF chromatin remodelling complex [nucleoplasm] (Homo sapiens)
SWI/SNF additional components [nucleoplasm] (Homo sapiens)
SMARCD2 [nucleoplasm] (Homo sapiens)
SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity (Homo sapiens)
SWI/SNF chromatin remodelling complex [nucleoplasm] (Homo sapiens)
SWI/SNF additional components [nucleoplasm] (Homo sapiens)
SMARCD2 [nucleoplasm] (Homo sapiens)
SWI/SNF chromatin remodelling complex:PRMT5:pT5-WDR77 [nucleoplasm] (Homo sapiens)
SWI/SNF chromatin remodelling complex [nucleoplasm] (Homo sapiens)
SWI/SNF additional components [nucleoplasm] (Homo sapiens)
SMARCD2 [nucleoplasm] (Homo sapiens)
Developmental Biology (Homo sapiens)
MITF-M-regulated melanocyte development (Homo sapiens)
MITF-M-dependent gene expression (Homo sapiens)
Regulation of MITF-M-dependent genes involved in pigmentation (Homo sapiens)
MITF-M and the SWI/SNF complex bind the TYR promoter (Homo sapiens)
BAF complex [nucleoplasm] (Homo sapiens)
SMARCD1,2,3 [nucleoplasm] (Homo sapiens)
SMARCD2 [nucleoplasm] (Homo sapiens)
M-MITF dimer:BAF complex:TYR gene [nucleoplasm] (Homo sapiens)
BAF complex [nucleoplasm] (Homo sapiens)
SMARCD1,2,3 [nucleoplasm] (Homo sapiens)
SMARCD2 [nucleoplasm] (Homo sapiens)
MITF-M dimer and the SWI/SNF complex bind the TYRP1 promoter (Homo sapiens)
BAF complex [nucleoplasm] (Homo sapiens)
SMARCD1,2,3 [nucleoplasm] (Homo sapiens)
SMARCD2 [nucleoplasm] (Homo sapiens)
MITF-M dimer:BAF complex:TYRP1 gene [nucleoplasm] (Homo sapiens)
BAF complex [nucleoplasm] (Homo sapiens)
SMARCD1,2,3 [nucleoplasm] (Homo sapiens)
SMARCD2 [nucleoplasm] (Homo sapiens)
MITF-M-dependent TYR gene expression (Homo sapiens)
M-MITF dimer:BAF complex:TYR gene [nucleoplasm] (Homo sapiens)
BAF complex [nucleoplasm] (Homo sapiens)
SMARCD1,2,3 [nucleoplasm] (Homo sapiens)
SMARCD2 [nucleoplasm] (Homo sapiens)
MITF-M-dependent TYRP1 gene expression (Homo sapiens)
MITF-M dimer:BAF complex:TYRP1 gene [nucleoplasm] (Homo sapiens)
BAF complex [nucleoplasm] (Homo sapiens)
SMARCD1,2,3 [nucleoplasm] (Homo sapiens)
SMARCD2 [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Regulation of endogenous retroelements (Homo sapiens)
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) (Homo sapiens)
DNMT3A:DNMT3L in nascent RNA transcript:MeR-PIWIL4:2'-O-methyl-piRNA:SPOCD1:DNMT3A:DNMT3L methylates cytosine in DNA (Homo sapiens)
nascent LINE-1 RNA transcript:MeR-PIWIL4:2'-O-methyl-piRNA:SPOCD1:DNMT3A:DNMT3L [nucleoplasm] (Homo sapiens)
BAF complex [nucleoplasm] (Homo sapiens)
SMARCD1,2,3 [nucleoplasm] (Homo sapiens)
SMARCD2 [nucleoplasm] (Homo sapiens)
PIWIL4:piRNA binds nascent LINE1 pre-RNA and recruits SPOCD1, C19ORF84, DNMT3A, DNMT3L, the NURD complex, and the BAF complex (Homo sapiens)
BAF complex [nucleoplasm] (Homo sapiens)
SMARCD1,2,3 [nucleoplasm] (Homo sapiens)
SMARCD2 [nucleoplasm] (Homo sapiens)
nascent LINE-1 RNA transcript:MeR-PIWIL4:2'-O-methyl-piRNA:SPOCD1:DNMT3A:DNMT3L [nucleoplasm] (Homo sapiens)
BAF complex [nucleoplasm] (Homo sapiens)
SMARCD1,2,3 [nucleoplasm] (Homo sapiens)
SMARCD2 [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by RUNX1 (Homo sapiens)
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known (Homo sapiens)
RUNX1 binds the SWI/SNF complex (Homo sapiens)
RUNX1:CBFB:SWI/SNF [nucleoplasm] (Homo sapiens)
SWI/SNF chromatin remodelling complex [nucleoplasm] (Homo sapiens)
SWI/SNF additional components [nucleoplasm] (Homo sapiens)
SMARCD2 [nucleoplasm] (Homo sapiens)
SWI/SNF chromatin remodelling complex [nucleoplasm] (Homo sapiens)
SWI/SNF additional components [nucleoplasm] (Homo sapiens)
SMARCD2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q92925 SMARCD2
Gene Names
SMARCD2, BAF60B, PRO2451
Chain
chain:1-531
Reference Genes
BioGPS Gene:6603 SMARCD2
COSMIC (genes):SMARCD2 SMARCD2
CTD Gene:6603 SMARCD2
dbSNP Gene:6603 SMARCD2
ENSEMBL:ENSG00000108604 SMARCD2
ENSEMBL_homo_sapiens_GENE:ENSG00000108604.18 SMARCD2
HGNC:11107 SMARCD2
KEGG Gene (Homo sapiens):6603 SMARCD2
Monarch:6603 SMARCD2
NCBI Gene:6603 SMARCD2
OMIM:601736 SMARCD2
UCSC:Q92925 SMARCD2
Reference Transcript
RefSeq:NM_001330440.1 SMARCD2
RefSeq:NM_001098426.1 SMARCD2
Other Identifiers
11717063_s_at
11742080_a_at
11747710_a_at
16847644
201827_PM_at
201827_at
34694_at
34695_at
3766416
3766417
3766418
3766419
3766420
3766422
3766423
3766425
3766426
3766428
3766429
3766431
3766432
3766433
3766437
3766438
3766439
3766440
455_at
6603
8017460
GE87462
GO:0000278
GO:0000776
GO:0000785
GO:0002376
GO:0003677
GO:0003712
GO:0003713
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0006281
GO:0006325
GO:0006337
GO:0006338
GO:0006351
GO:0006355
GO:0006357
GO:0007059
GO:0007155
GO:0016363
GO:0016514
GO:0016586
GO:0030071
GO:0030154
GO:0031492
GO:0032991
GO:0035060
GO:0043226
GO:0045582
GO:0045597
GO:0045663
GO:0045893
GO:0048856
GO:0070316
GO:0140092
GO:0140110
GO:2000045
GO:2000781
GO:2000819
HMNXSV003012771
ILMN_1692684
PH_hs_0013265
TC17001787.hg
U66618_at
g6642761_3p_at
Participates
as a member of
SMARCD1,2,3 [nucleoplasm] (Homo sapiens)
as a candidate of
SWI/SNF additional components [nucleoplasm] (Homo sapiens)
Inferred To
SNF12 [nucleoplasm]
(Saccharomyces cerevisiae)
snf12-1 [nucleoplasm]
(Dictyostelium discoideum)
swsn-2.2 [nucleoplasm]
(Caenorhabditis elegans)
Smarcd2 [nucleoplasm]
(Mus musculus)
Smarcd2 [nucleoplasm]
(Rattus norvegicus)
smarcd2 [nucleoplasm]
(Xenopus tropicalis)
ham-3 [nucleoplasm]
(Caenorhabditis elegans)
ssr3 [nucleoplasm]
(Schizosaccharomyces pombe)
Bap60 [nucleoplasm]
(Drosophila melanogaster)
Homologues of SMARCD2 [nucleoplasm]
(Caenorhabditis elegans)
Homologues of SMARCD2 [nucleoplasm]
(Saccharomyces cerevisiae)
RSC6 [nucleoplasm]
(Saccharomyces cerevisiae)
SMARCD2 [nucleoplasm]
(Bos taurus)
SMARCD2 [nucleoplasm]
(Canis familiaris)
SMARCD2 [nucleoplasm]
(Gallus gallus)
SMARCD2 [nucleoplasm]
(Sus scrofa)
Cross References
RefSeq
NP_001091896.1
,
NP_001317369.1
OpenTargets
ENSG00000108604
GeneCards
Q92925
HPA
ENSG00000108604-SMARCD2
Ensembl
ENSP00000318451
,
ENST00000448276
,
ENSG00000108604
,
ENSP00000392617
,
ENST00000323347
PRO
Q92925
Pharos - Targets
Q92925
Orphanet
26299
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q01201 RELB
2
RELB [nucleoplasm]
(R-HSA-5607656)
RELB [cytosol]
(R-HSA-5607652)
0.564
2
UniProt:P51532 SMARCA4
1
SMARCA4 [nucleoplasm]
(R-HSA-201686)
0.527
3
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