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SEC61G [cytosol]
Stable Identifier
R-HSA-5250558
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
SEC61 gamma
Locations in the PathwayBrowser
Expand all
Protein localization (Homo sapiens)
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane (Homo sapiens)
SGTA binds Tail-anchored protein (Homo sapiens)
Tail-anchored protein:SGTA dimer [cytosol] (Homo sapiens)
Tail-anchored proteins [cytosol] (Homo sapiens)
SEC61G [cytosol] (Homo sapiens)
Tail-anchored proteins [cytosol] (Homo sapiens)
SEC61G [cytosol] (Homo sapiens)
Tail-anchored protein:ASNA1:ADP binds WRB:CAMLG at the endoplasmic reticulum membrane (Homo sapiens)
Tail-anchored protein:ASNA1:ADP [cytosol] (Homo sapiens)
Tail-anchored proteins [cytosol] (Homo sapiens)
SEC61G [cytosol] (Homo sapiens)
Tail-anchored protein:ASNA1:ADP:WRB:CAMLG [endoplasmic reticulum membrane] (Homo sapiens)
Tail-anchored protein:ASNA1:ADP [cytosol] (Homo sapiens)
Tail-anchored proteins [cytosol] (Homo sapiens)
SEC61G [cytosol] (Homo sapiens)
Tail-anchored protein:ASNA1:ADP:WRB:CAMLG dissociates yielding Tail-anchored protein in the endoplasmic reticulum membrane (Homo sapiens)
Tail-anchored protein:ASNA1:ADP:WRB:CAMLG [endoplasmic reticulum membrane] (Homo sapiens)
Tail-anchored protein:ASNA1:ADP [cytosol] (Homo sapiens)
Tail-anchored proteins [cytosol] (Homo sapiens)
SEC61G [cytosol] (Homo sapiens)
Tail-anchored protein:SGTA dimer binds BAG6:GET4:UBL4A and ASNA1:ATP (Homo sapiens)
Tail-anchored protein:SGTA dimer [cytosol] (Homo sapiens)
Tail-anchored proteins [cytosol] (Homo sapiens)
SEC61G [cytosol] (Homo sapiens)
Tail-anchored protein:SGTA:BAG6:GET4:UBL4A:ASNA1:ATP [cytosol] (Homo sapiens)
Tail-anchored protein:SGTA dimer [cytosol] (Homo sapiens)
Tail-anchored proteins [cytosol] (Homo sapiens)
SEC61G [cytosol] (Homo sapiens)
Tail-anchored protein:SGTA:BAG6:GET4:UBL4A:ASNA1:ATP dissociates and ASNA1 hydrolyzes ATP yielding Tail-anchored protein:ASNA1:ADP (Homo sapiens)
Tail-anchored protein:ASNA1:ADP [cytosol] (Homo sapiens)
Tail-anchored proteins [cytosol] (Homo sapiens)
SEC61G [cytosol] (Homo sapiens)
Tail-anchored protein:ASNA1:ATP [cytosol] (Homo sapiens)
Tail-anchored proteins [cytosol] (Homo sapiens)
SEC61G [cytosol] (Homo sapiens)
Tail-anchored protein:SGTA:BAG6:GET4:UBL4A:ASNA1:ATP [cytosol] (Homo sapiens)
Tail-anchored protein:SGTA dimer [cytosol] (Homo sapiens)
Tail-anchored proteins [cytosol] (Homo sapiens)
SEC61G [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P60059 SEC61G
Gene Names
SEC61G
Chain
chain:1-68
Reference Genes
BioGPS Gene:23480 SEC61G
COSMIC (genes):SEC61G SEC61G
CTD Gene:23480 SEC61G
dbSNP Gene:23480 SEC61G
ENSEMBL:ENSG00000132432 SEC61G
ENSEMBL:ENSG00000132432.14 SEC61G
HGNC:18277 SEC61G
KEGG Gene (Homo sapiens):23480 SEC61G
Monarch:23480 SEC61G
NCBI Gene:23480 SEC61G
OMIM:609215 SEC61G
UCSC:P60059 SEC61G
Reference Transcript
RefSeq:NM_014302.3 SEC61G
RefSeq:NM_001012456.1 SEC61G
Other Identifiers
11716223_a_at
17057884
203484_PM_at
203484_at
23480
3051400
3051405
3051407
3051409
3051410
3051411
39169_at
8139706
A_23_P71241
GE61207
GO:0005215
GO:0005515
GO:0005783
GO:0005789
GO:0005829
GO:0006605
GO:0006886
GO:0008320
GO:0015031
GO:0016020
GO:0031204
GO:0043022
GO:0043226
GO:0045047
GO:0055085
GO:0071261
GO:0071806
HMNXSV003055707
ILMN_1787026
ILMN_2367020
PH_hs_0001028
g7657545_3p_at
Participates
as a member of
Tail-anchored proteins [cytosol] (Homo sapiens)
Other forms of this molecule
SEC61G [endoplasmic reticulum membrane]
SEC61G [phagocytic vesicle membrane]
Inferred To
sec-61.G [cytosol]
(Caenorhabditis elegans)
Sec61g [cytosol]
(Mus musculus)
Sec61g [cytosol]
(Rattus norvegicus)
sec61g [cytosol]
(Dictyostelium discoideum)
SSS1 [cytosol]
(Saccharomyces cerevisiae)
Sec61gamma [cytosol]
(Drosophila melanogaster)
sss1 [cytosol]
(Schizosaccharomyces pombe)
zgc:92840 [cytosol]
(Danio rerio)
SEC61G [cytosol]
(Bos taurus)
SEC61G [cytosol]
(Canis familiaris)
SEC61G [cytosol]
(Gallus gallus)
SEC61G [cytosol]
(Plasmodium falciparum)
SEC61G [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_001012474.1
,
NP_055117.1
OpenTargets
ENSG00000132432
GeneCards
P60059
HPA
ENSG00000132432-SEC61G
Ensembl
ENSP00000378906
,
ENST00000352861
,
ENSP00000341538
,
ENST00000450622
,
ENST00000415949
,
ENSG00000132432
,
ENSP00000409884
,
ENST00000395535
,
ENSP00000388337
PRO
P60059
Pharos - Targets
P60059
PDB
6W6L
,
8B6L
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P11686 SFTPC
9
pro-SFTPC P115L [endoplasmic reticulum membrane]
(R-HSA-5688352)
pro-SFTPC P30L [endoplasmic reticulum membrane]
(R-HSA-5688365)
pro-SFTPC [endoplasmic reticulum membrane]
(R-HSA-5683842)
pro-SFTPC [multivesicular body lumen]
(R-HSA-5685298)
SFTPC [extracellular region]
(R-HSA-5683685)
SFTPC [clathrin-coated endocytic vesicle]
(R-HSA-5686342)
SFTPC [lamellar body]
(R-HSA-5683717)
SFTPC(24-58) [multivesicular body lumen]
(R-HSA-5685899)
SFTPC(59-197) [multivesicular body lumen]
(R-HSA-5685871)
0.556
3
UniProt:Q96BA8 CREB3L1
7
CREB3L1 [Golgi membrane]
(R-HSA-8874155)
CREB3L1(427-519) [Golgi membrane]
(R-HSA-8874139)
CREB3L1(1-426) [Golgi membrane]
(R-HSA-8874153)
CREB3L1 [endoplasmic reticulum membrane]
(R-HSA-8874157)
CREB3L1(1-375) [cytosol]
(R-HSA-8874215)
CREB3L1(376-426) [Golgi membrane]
(R-HSA-8874213)
CREB3L1(1-375) [nucleoplasm]
(R-HSA-8874222)
0.556
5
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