Reactome | SEC61B [cytosol]

SEC61B [cytosol]

Stable Identifier

R-HSA-5250571

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

SEC61 beta

External Reference Information

External Reference

UniProt:P60468 SEC61B

Gene Names

SEC61B

Chain

initiator methionine:, chain:2-96

Reference Genes

BioGPS Gene:10952 SEC61B

COSMIC (genes):SEC61B SEC61B

CTD Gene:10952 SEC61B

dbSNP Gene:10952 SEC61B

ENSEMBL:ENSG00000106803 SEC61B

ENSEMBL_homo_sapiens_GENE:ENSG00000106803.10 SEC61B

HGNC:16993 SEC61B

KEGG Gene (Homo sapiens):10952 SEC61B

Monarch:10952 SEC61B

NCBI Gene:10952 SEC61B

OMIM:609214 SEC61B

UCSC:P60468 SEC61B

Reference Transcript

RefSeq:NM_006808.2 SEC61B

Other Identifiers

10952

11716938_a_at

17087498

203133_PM_at

203133_at

3181803

3181804

3181805

3181814

3181815

3181816

3181817

3181818

3181819

32564_at

3372540

8156838

A_23_P135342

A_24_P8494

GO:0003723

GO:0005515

GO:0005783

GO:0005784

GO:0005789

GO:0005829

GO:0006616

GO:0006886

GO:0015031

GO:0016020

GO:0030163

GO:0030433

GO:0030970

GO:0031204

GO:0031205

GO:0043022

GO:0043226

GO:0044322

GO:0048408

GO:0055085

HMNXSV003035178

ILMN_1801852

L25085_at

PH_hs_0011293

PH_hs_0032087

TC09000502.hg

g5803164_3p_at

Participates

as a component of

BAG6:GET4:UBL4A:SEC61B [cytosol] (Homo sapiens)

as an input of

BAG6:GET4:UBL4A binds SEC61B (Homo sapiens)

as a member of

Tail-anchored proteins [cytosol] (Homo sapiens)

Other forms of this molecule

SEC61B [endoplasmic reticulum membrane]

SEC61B [phagocytic vesicle membrane]

Inferred To

Sec61b [cytosol] (Mus musculus)

Sec61b [cytosol] (Rattus norvegicus)

sbh1 [cytosol] (Schizosaccharomyces pombe)

sec61b [cytosol] (Danio rerio)

sec61b [cytosol] (Dictyostelium discoideum)

sec61b [cytosol] (Xenopus tropicalis)

Homologues of SEC61B [cytosol] (Mus musculus)

Sec61beta [cytosol] (Drosophila melanogaster)

sec-61.b [cytosol] (Caenorhabditis elegans)

SBH2 [cytosol] (Saccharomyces cerevisiae)

SEC61B [cytosol] (Bos taurus)

SEC61B [cytosol] (Canis familiaris)

SEC61B [cytosol] (Gallus gallus)

SEC61B [cytosol] (Mus musculus)

SEC61B [cytosol] (Plasmodium falciparum)

SEC61B [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_006799.1

OpenTargets

ENSG00000106803

HPA

ENSG00000106803-SEC61B

GeneCards

P60468

Ensembl

ENSP00000223641, ENSG00000106803, ENST00000223641

PRO

P60468

Pharos - Targets

P60468

PDB

8OJ8, 8DO2, 8DO0, 8DNW, 8DNY, 8OJ0, 6W6L, 8DO3, 8DO1, 8DNV, 8DNX, 8B6L, 8DNZ

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q12154 GET3	1	GET3 [cytosol] (R-SCE-9628623)	0.683	4
UniProt:P0DTD8 NS7B			0.623	3
UniProt:P51572 BCAP31	6	BCAP31 [lumenal side of endoplasmic reticulum membrane] (R-HSA-985503) BCAP31 [endoplasmic reticulum membrane] (R-HSA-9714333) BCAP31(2-245) [endoplasmic reticulum membrane] (R-HSA-201587) BCAP31(165-237) [endoplasmic reticulum membrane] (R-HSA-351909) BCAP31(2-164) [endoplasmic reticulum membrane] (R-HSA-351826) BCAP31(238-246) [cytosol] (R-HSA-351912)	0.602	7
UniProt:Q9H9S3 SEC61A2	2	SEC61A2 [endoplasmic reticulum membrane] (R-HSA-444585) SEC61A2 [phagocytic vesicle membrane] (R-HSA-1236771)	0.564	2
UniProt:P43307 SSR1	1	SSR1 [endoplasmic reticulum membrane] (R-HSA-444588)	0.564	2
UniProt:P53618 COPB1	8	COPB1 [endoplasmic reticulum membrane] (R-HSA-6810955) COPB1 [Golgi membrane] (R-HSA-6808735) COPB1 [transport vesicle] (R-HSA-6808736) COPB1 [cytosol] (R-HSA-199995) COPB1 [ficolin-1-rich granule membrane] (R-HSA-6800972) COPB1 [secretory granule membrane] (R-HSA-6800914) COPB1 [plasma membrane] (R-HSA-6806431) COPB1 [tertiary granule membrane] (R-HSA-6800175)	0.527	2

Cite Us!