APC R1450* [cytosol]

Stable Identifier
R-HSA-5251499
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Adenomatous polyposis coli protein, APC_HUMAN, SW403
APC R1450* [cytosol] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
11746989 Frequent alterations in the Wnt signaling pathway in colorectal cancer with microsatellite instability

Kodama, S, Fujimori, M, Ikeda, S, Nakahara, M, Okajima, M, Asahara, T, Shimizu, Y

Genes Chromosomes Cancer 2002
1338904 Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene

Mori, T, Ando, H, Nagase, H, Ichii, S, Horii, A, Nakamura, Y, Nakatsuru, S, Miyoshi, Y, Miki, Y, Aoki, T

Hum. Mol. Genet. 1992
External Reference Information
External Reference
Gene Names
APC, DP2.5
Chain
initiator methionine:1, chain:2-2843
Other Identifiers
0004920746
11731561_a_at
11731562_s_at
11757692_s_at
16988021
1912_s_at
203525_s_at
203526_s_at
203527_s_at
216933_3p_x_at
216933_x_at
2824218
2824220
2824225
2824230
2824232
2824233
2824239
2824244
2824245
2824248
2824253
2824256
2824257
2824258
2824266
2824267
2824268
2824272
2824273
2824274
2824275
2824276
2824277
2824279
324
36182_at
8107330
A_14_P106747
A_14_P116796
A_14_P135872
A_23_P70213
A_33_P3408983
GE58061
GO:0000278
GO:0000281
GO:0000776
GO:0001708
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005794
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0005874
GO:0005881
GO:0005886
GO:0005912
GO:0005923
GO:0006464
GO:0006950
GO:0006974
GO:0007010
GO:0007026
GO:0007049
GO:0007050
GO:0007059
GO:0007094
GO:0007155
GO:0007165
GO:0007267
GO:0007389
GO:0007399
GO:0008013
GO:0008017
GO:0008092
GO:0008150
GO:0008219
GO:0008283
GO:0008285
GO:0008286
GO:0009056
GO:0010942
GO:0016020
GO:0016055
GO:0016328
GO:0016342
GO:0016477
GO:0016579
GO:0019887
GO:0019899
GO:0019901
GO:0022607
GO:0030027
GO:0030054
GO:0030154
GO:0030178
GO:0030234
GO:0030335
GO:0030877
GO:0031274
GO:0031625
GO:0032587
GO:0032886
GO:0032991
GO:0034330
GO:0040011
GO:0042592
GO:0042995
GO:0043065
GO:0043226
GO:0045295
GO:0045595
GO:0045732
GO:0045736
GO:0048471
GO:0048856
GO:0048870
GO:0051010
GO:0051276
GO:0051301
GO:0051988
GO:0065003
GO:0070830
GO:0070840
GO:0090090
GO:0120162
GO:0140014
GO:1904781
GO:1904885
GO:1904886
GO:1990909
GO:2000134
HMNXSV003016363
Hs.75081.0.S2_3p_a_at
Hs.75081.1.S1_3p_a_at
ILMN_1662668
M73548_at
M74088_s_at
PH_hs_0031313
TC05003398.hg
g182396_3p_a_at
g4557318_3p_a_at
Participates
Other forms of this molecule
Modified Residues
Name
L-arginine 1450 replaced with unknown
Coordinate
1450
PsiMod
A protein modification that effectively removes or replaces an L-arginine.
Disease
Name Identifier Synonyms
colorectal cancer DOID:9256
Interactors (23)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P35222 CTNNB1  20 0.953 19
 UniProt:O15169 AXIN1  11 0.845 17
 UniProt:Q15691 MAPRE1  1 0.775 5
 UniProt:P49841 GSK3B  4 0.763 5
 UniProt:P49674 CSNK1E  2 0.738 8
 UniProt:Q5JTC6 AMER1  5 0.723 4
 UniProt:Q14160 SCRIB  1 0.697 5
 UniProt:P60953 CDC42  3 0.668 9
 UniProt:Q96N96 SPATA13  1 0.667 5
 UniProt:Q07666 KHDRBS1  3 0.667 4
 UniProt:Q9NR80-3 ARHGEF4      0.646 5
 UniProt:Q13363 CTBP1  3 0.643 3
 UniProt:P14923 JUP  6 0.64 3
 UniProt:P35221 CTNNA1  2 0.64 3
 UniProt:Q8N944 AMER3      0.631 8
 UniProt:O14640 DVL1  4 0.623 6
 UniProt:Q02248 Ctnnb1  12 0.623 8
 UniProt:Q12959 DLG1  4 0.623 2
 UniProt:Q96N96-1 SPATA13      0.619 5
 UniProt:O14641 DVL2  5 0.564 2
 UniProt:Q9NSA3 CTNNBIP1  1 0.564 2
 UniProt:Q14114 LRP8  2 0.558 2
 IntAct:EBI-6876712 CTNB1      0.499 6
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