Reactome | GPR37 [plasma membrane]

GPR37 [plasma membrane]

Stable Identifier

R-HSA-5333623

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Prosaposin receptor GPR37, GPR37_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O15354 GPR37

Gene Names

GPR37

Chain

signal peptide:1-26, chain:27-613

Reference Genes

BioGPS Gene:2861 GPR37

COSMIC (genes):GPR37 GPR37

CTD Gene:2861 GPR37

dbSNP Gene:2861 GPR37

ENSEMBL:ENSG00000170775.3 GPR37

HGNC:4494 GPR37

KEGG Gene (Homo sapiens):2861 GPR37

Monarch:2861 GPR37

NCBI Gene:2861 GPR37

OMIM:602583 GPR37

UCSC:O15354 GPR37

Reference Transcript

RefSeq:NM_005302.3 GPR37

Other Identifiers

0004570315

0102760167

11737992_s_at

11751962_s_at

17062491

209631_PM_s_at

209631_s_at

214586_PM_at

214586_at

2861

3070870

3070872

3070874

3070875

3070876

3070877

3070878

3070879

3070890

3070891

3070892

3070893

3070894

3070895

34297_at

47220_at

8142687

ADDON002490.hg

A_23_P145995

GE59516

GO:0000151

GO:0004930

GO:0005515

GO:0005622

GO:0005737

GO:0005783

GO:0005789

GO:0005886

GO:0005887

GO:0007165

GO:0007186

GO:0007193

GO:0007218

GO:0008188

GO:0008528

GO:0009986

GO:0016020

GO:0016021

GO:0016358

GO:0023052

GO:0030154

GO:0030165

GO:0030544

GO:0031072

GO:0031625

GO:0031987

GO:0032991

GO:0036505

GO:0042277

GO:0042416

GO:0042923

GO:0043226

GO:0043235

GO:0043410

GO:0045202

GO:0045964

GO:0048856

GO:0060089

GO:1903206

HMNXSV003051472

Hs.27747.1.S2_3p_at

ILMN_1668271

ILMN_1905482

ILMN_2218935

PH_hs_0019248

TC07001828.hg

TC07003146.hg

U87460_at

g2076881_3p_a_at

Participates

as an input of

GPR37 binds prosaptide (Homo sapiens)

as a component of

GPR37:PSAP fragments [plasma membrane] (Homo sapiens)

Inferred To

GPR37 [plasma membrane] (Bos taurus)

GPR37 [plasma membrane] (Canis familiaris)

GPR37 [plasma membrane] (Gallus gallus)

GPR37 [plasma membrane] (Sus scrofa)

Gpr37 [plasma membrane] (Mus musculus)

Gpr37 [plasma membrane] (Rattus norvegicus)

si:dkey-3n7.1 [plasma membrane] (Danio rerio)

gpr37 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_005293.1

Guide to Pharmacology - Targets

103

OpenTargets

ENSG00000170775

GeneCards

O15354

HPA

ENSG00000170775-GPR37

Ensembl

ENSG00000170775, ENSP00000306449, ENST00000303921

PRO

O15354

Pharos - Targets

O15354

Interactors (25)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P29274 ADORA2A	2	ADORA2A [Golgi membrane] (R-HSA-187668) ADORA2A [plasma membrane] (R-HSA-418934)	0.581	3
UniProt:P08195 SLC3A2	1	SLC3A2 [plasma membrane] (R-HSA-352179)	0.581	3
UniProt:Q13639 HTR4	1	HTR4 [plasma membrane] (R-HSA-391008)	0.581	5
UniProt:Q14671 PUM1	1	PUM1 [cytosol] (R-HSA-434211)	0.556	3
UniProt:O15540 FABP7	1	FABP7 [cytosol] (R-HSA-5216158)	0.556	3
UniProt:Q14995 NR1D2	1	NR1D2 [nucleoplasm] (R-HSA-375501)	0.556	3
UniProt:Q9C0A1 ZFHX2			0.556	3
UniProt:Q5TA79 LCE2A	1	LCE2A [cytosol] (R-HSA-6814264)	0.556	3
UniProt:Q7Z7K5 Q7Z7K5			0.556	3
UniProt:P25490 YY1	1	YY1 [nucleoplasm] (R-HSA-4086091)	0.556	3
UniProt:A0A024R4B0 A0A024R4B0			0.556	3
UniProt:Q02930-3 CREB5			0.556	3
UniProt:D3DTF8 D3DTF8			0.556	3
UniProt:P34741 SDC2	20	SDC2 [plasma membrane] (R-HSA-2090052) p-Y179,Y191-SDC2 [plasma membrane] (R-HSA-4093306) SDC2 [lysosomal lumen] (R-HSA-2090083) HS(6)-SDC2 [lysosomal lumen] (R-HSA-2090064) HS(6)-SDC2 [Golgi lumen] (R-HSA-2076588) HS(5)-SDC2 [Golgi lumen] (R-HSA-2076320) Heparan-SDC2 [Golgi lumen] (R-HSA-2076608) Heparan(1)-SDC2 [Golgi lumen] (R-HSA-2076536) Heparan(2)-SDC2 [Golgi lumen] (R-HSA-2076397) Heparan(3)-SDC2 [Golgi lumen] (R-HSA-2076361) Heparan(4)-SDC2 [Golgi lumen] (R-HSA-2076576) HS(1)-SDC2 [Golgi lumen] (R-HSA-2076607) HS(2)-SDC2 [Golgi lumen] (R-HSA-2076603) HS(4)-SDC2 [Golgi lumen] (R-HSA-2076356) HS(3)-SDC2 [Golgi lumen] (R-HSA-2076443) HS(4)-SDC2 [plasma membrane] (R-HSA-2076683) HS(6)-SDC2 [plasma membrane] (R-HSA-2076661) HS(2)-SDC2 [plasma membrane] (R-HSA-2076644) HS(1)-SDC2 [plasma membrane] (R-HSA-2076643) HS(3)-SDC2 [plasma membrane] (R-HSA-2076631)	0.556	3
UniProt:Q7L8T7 Q7L8T7			0.556	3
UniProt:Q8IXL7-2 MSRB3			0.556	3
UniProt:Q5HYJ3-3 FAM76B			0.556	3
UniProt:Q71RG4-4 Q71RG44			0.556	3
UniProt:Q969E2 SCAM4			0.556	3
UniProt:Q01959 SLC6A3	5	SLC6A3 [plasma membrane] (R-HSA-379482) SLC6A3 L368Q [plasma membrane] (R-HSA-5660710) SLC6A3 L224P [plasma membrane] (R-HSA-5660718) SLC6A3 P395L [plasma membrane] (R-HSA-5660716) SLC6A3 R521W [plasma membrane] (R-HSA-5660729)	0.524	2
UniProt:Q9UBS5 GABBR1	1	GABBR1 [plasma membrane] (R-HSA-420716)	0.508	2
UniProt:O95070 YIF1A	1	YIF1A [endoplasmic reticulum membrane] (R-HSA-535599)	0.508	2
UniProt:Q5BJH7 YIF1B			0.508	2
UniProt:Q9H313 TTYH1			0.508	2
UniProt:Q9NX61 T161A			0.508	2