Reactome | GPR37 [plasma membrane]

GPR37 [plasma membrane]

Stable Identifier

R-HSA-5333623

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Prosaposin receptor GPR37, GPR37_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P08195 SLC3A2

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External Reference Information

External Reference

UniProt:O15354 GPR37

Gene Names

GPR37

Chain

signal peptide:1-26, chain:27-613

Reference Genes

BioGPS Gene:2861 GPR37

COSMIC (genes):GPR37 GPR37

CTD Gene:2861 GPR37

dbSNP Gene:2861 GPR37

ENSEMBL:ENSG00000170775 GPR37

HGNC:4494 GPR37

KEGG:hsa:2861 GPR37

Monarch:2861 GPR37

NCBI Gene:2861 GPR37

OMIM:602583 GPR37

UCSC:O15354 GPR37

Reference Transcript

RefSeq:NM_005302.3 GPR37

Other Identifiers

11737992_s_at

11751962_s_at

17062491

209631_PM_s_at

209631_s_at

214586_PM_at

214586_at

2861

3070870

3070872

3070874

3070875

3070876

3070877

3070878

3070879

3070890

3070891

3070892

3070893

3070894

3070895

34297_at

47220_at

8142687

ADDON002490.hg

A_23_P145995

GE59516

GO:0000151

GO:0004930

GO:0005515

GO:0005737

GO:0005783

GO:0005789

GO:0005886

GO:0007186

GO:0007193

GO:0007218

GO:0008188

GO:0008528

GO:0009986

GO:0016020

GO:0016358

GO:0030165

GO:0030425

GO:0030544

GO:0031072

GO:0031625

GO:0031987

GO:0034614

GO:0036505

GO:0042277

GO:0042416

GO:0042923

GO:0042995

GO:0043226

GO:0043235

GO:0043410

GO:0045202

GO:0045964

GO:0048856

GO:0060089

HMNXSV003051472

Hs.27747.1.S2_3p_at

ILMN_1905482

ILMN_2218935

PH_hs_0019248

TC07001828.hg

TC07003146.hg

U87460_at

g2076881_3p_a_at

Participates

as an input of

GPR37 binds prosaptide (Homo sapiens)

as a component of

GPR37:PSAP fragments [plasma membrane] (Homo sapiens)

Inferred To

GPR37 [plasma membrane] (Bos taurus)

GPR37 [plasma membrane] (Canis familiaris)

GPR37 [plasma membrane] (Gallus gallus)

GPR37 [plasma membrane] (Sus scrofa)

Gpr37 [plasma membrane] (Mus musculus)

Gpr37 [plasma membrane] (Rattus norvegicus)

gpr37 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_005293.1

Guide to Pharmacology - Targets

103

OpenTargets

ENSG00000170775

ENSEMBL

ENSG00000170775, ENSP00000306449, ENST00000303921

HPA

ENSG00000170775-GPR37

GeneCards

GPR37

PRO

O15354

Pharos - Targets

O15354

GlyGen

O15354

Interactors (28)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P29274 ADORA2A	2	ADORA2A [plasma membrane] (R-HSA-418934) ADORA2A [Golgi membrane] (R-HSA-187668)	0.581	3
UniProt:P08195 SLC3A2	1	SLC3A2 [plasma membrane] (R-HSA-352179)	0.581	3
UniProt:Q13639 HTR4	1	HTR4 [plasma membrane] (R-HSA-391008)	0.581	5
UniProt:P25490 YY1	1	YY1 [nucleoplasm] (R-HSA-4086091)	0.556	3
UniProt:Q14995 NR1D2	1	NR1D2 [nucleoplasm] (R-HSA-375501)	0.556	3
UniProt:Q9C0A1 ZFHX2			0.556	3
UniProt:Q5TA79 LCE2A	1	LCE2A [cytosol] (R-HSA-6814264)	0.556	3
UniProt:Q7Z7K5 Q7Z7K5			0.556	3
UniProt:APLN D3DTF8			0.556	3
UniProt:Q02930-3 CREB5			0.556	3
UniProt:SPATA3 A0A024R4B0			0.556	3
UniProt:P34741 SDC2	20	HS(4)-SDC2 [plasma membrane] (R-HSA-2076683) HS(6)-SDC2 [plasma membrane] (R-HSA-2076661) HS(2)-SDC2 [plasma membrane] (R-HSA-2076644) HS(1)-SDC2 [plasma membrane] (R-HSA-2076643) HS(3)-SDC2 [plasma membrane] (R-HSA-2076631) HS(5)-SDC2 [plasma membrane] (R-HSA-2076665) SDC2 [endoplasmic reticulum lumen] (R-HSA-8956741) p-SDC2 [endoplasmic reticulum lumen] (R-HSA-8956945) SDC2 [Golgi lumen] (R-HSA-2054101) XylS-SDC2 [Golgi lumen] (R-HSA-2064109) Gal-Xyl-SDC2 [Golgi lumen] (R-HSA-2064132) Gal-Gal-Xyl-SDC2 [Golgi lumen] (R-HSA-2063988) GlcA-Gal-Gal-Xyl-SDC2 [Golgi lumen] (R-HSA-2063997) HS(2)-SDC2 [Golgi lumen] (R-HSA-2076603) HS(3)-SDC2 [Golgi lumen] (R-HSA-2076443) HS(1)-SDC2 [Golgi lumen] (R-HSA-2076607) Heparan(4)-SDC2 [Golgi lumen] (R-HSA-2076576) Heparan(3)-SDC2 [Golgi lumen] (R-HSA-2076361) Heparan(2)-SDC2 [Golgi lumen] (R-HSA-2076397) Heparan(1)-SDC2 [Golgi lumen] (R-HSA-2076536)	0.556	3
UniProt:Q7L8T7 Q7L8T7			0.556	3
UniProt:Q8IXL7-2 MSRB3			0.556	3
UniProt:Q5HYJ3-3 FAM76B			0.556	3
UniProt:Q71RG4-4 Q71RG44			0.556	3
UniProt:Q969E2 SCAM4			0.556	3
UniProt:O15540 FABP7	1	FABP7 [cytosol] (R-HSA-5216158)	0.556	3
UniProt:Q14671 PUM1	1	PUM1 [cytosol] (R-HSA-434211)	0.556	3
UniProt:Q8IWB7 WDFY1			0.527	2
UniProt:Q9UBU9 NXF1	2	NXF1 [nucleoplasm] (R-HSA-111690) NXF1 [cytosol] (R-HSA-156481)	0.527	2
UniProt:O95260 ATE1			0.527	2
UniProt:Q01959 SLC6A3	5	SLC6A3 [plasma membrane] (R-HSA-379482) SLC6A3 L368Q [plasma membrane] (R-HSA-5660710) SLC6A3 L224P [plasma membrane] (R-HSA-5660718) SLC6A3 P395L [plasma membrane] (R-HSA-5660716) SLC6A3 R521W [plasma membrane] (R-HSA-5660729)	0.524	2
UniProt:Q5BJH7 YIF1B			0.508	2
UniProt:O95070 YIF1A	1	YIF1A [endoplasmic reticulum membrane] (R-HSA-535599)	0.508	2
UniProt:Q9H313 TTYH1			0.508	2
UniProt:Q9NX61 T161A			0.508	2
UniProt:Q9UBS5 GABBR1	1	GABBR1 [plasma membrane] (R-HSA-420716)	0.508	2

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