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CD9 [endocytic vesicle membrane]
Stable Identifier
R-HSA-5334774
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endocytic vesicle membrane
Synonyms
P24, Leukocyte antigen MIC3, Motility-related protein, MRP-1, CD9 antigen
Icon
Locations in the PathwayBrowser for interactor UniProt:P62079 TSPAN5
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Uptake and actions of bacterial toxins (Homo sapiens)
Uptake and function of diphtheria toxin (Homo sapiens)
DT fragment B transports DT fragment A from target cell endosome membrane (Homo sapiens)
CD9 [endocytic vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P21926 CD9
Gene Names
CD9, MIC3, TSPAN29, GIG2
Chain
initiator methionine:, chain:2-228
Reference Genes
BioGPS Gene:928 CD9
COSMIC (genes):CD9 CD9
CTD Gene:928 CD9
dbSNP Gene:928 CD9
ENSEMBL:ENSG00000010278 CD9
ENSEMBL_homo_sapiens_GENE:ENSG00000010278.15 CD9
HGNC:1709 CD9
KEGG Gene (Homo sapiens):928 CD9
Monarch:928 CD9
NCBI Gene:928 CD9
OMIM:143030 CD9
UCSC:P21926 CD9
Reference Transcript
RefSeq:NM_001769.3 CD9
RefSeq:NM_001330312.1 CD9
Other Identifiers
11715568_a_at
11715569_at
11715570_x_at
11746940_a_at
11763854_a_at
11763855_x_at
16747184
201005_PM_at
201005_at
3402318
3402319
3402320
3402321
3402322
3402335
3402337
3402339
3402341
3402343
3402347
3402350
3402351
3402352
39389_at
7953291
928
A_14_P120677
A_14_P129314
A_23_P76364
GE79033
GO:0002376
GO:0005178
GO:0005515
GO:0005576
GO:0005615
GO:0005886
GO:0005925
GO:0007155
GO:0007338
GO:0007342
GO:0008283
GO:0008285
GO:0008347
GO:0009897
GO:0009986
GO:0014905
GO:0016020
GO:0016192
GO:0022414
GO:0030154
GO:0030168
GO:0030666
GO:0030669
GO:0030913
GO:0031092
GO:0031410
GO:0031623
GO:0032991
GO:0034330
GO:0035036
GO:0042060
GO:0043226
GO:0048856
GO:0048870
GO:0061024
GO:0070062
GO:0071404
GO:0090331
GO:1903561
GO:1905521
HMNXSV003037369
HMNXSV003043182
ILMN_1695423
M38690_at
PH_hs_0024428
TC12000076.hg
g4502692_3p_x_at
Participates
as an output of
DT fragment B transports DT fragment A from target cell endosome membrane (Homo sapiens)
as a component of
DT:HBEGF:CD9 [endocytic vesicle membrane] (Homo sapiens)
Other forms of this molecule
CD9 [plasma membrane]
CD9 [clathrin-coated endocytic vesicle membrane]
CD9 [platelet alpha granule membrane]
Cross References
RefSeq
NP_001760.1
,
NP_001317241.1
OpenTargets
ENSG00000010278
HPA
ENSG00000010278-CD9
GeneCards
P21926
Ensembl
ENSP00000009180
,
ENSG00000010278
,
ENST00000538834
,
ENST00000009180
,
ENST00000382518
,
ENSP00000496639
,
ENSP00000371958
PRO
P21926
Pharos - Targets
P21926
PDB
6RLO
,
6Z1V
,
6Z20
,
6K4J
,
6RLR
Interactors (39)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9P2B2 FPRP
0.859
11
UniProt:P60033 CD81
1
CD81 [plasma membrane]
(R-HSA-197933)
0.758
7
UniProt:Q969P0 IGSF8
0.758
7
UniProt:O14672 ADAM10
6
ADAM10(215-824) [plasma membrane]
(R-HSA-179885)
ADAM10 [plasma membrane]
(R-HSA-157237)
ADAM10 [endoplasmic reticulum lumen]
(R-HSA-8956768)
p-ADAM10 [endoplasmic reticulum lumen]
(R-HSA-8956999)
ADAM10 [tertiary granule membrane]
(R-HSA-6800992)
ADAM10 [specific granule membrane]
(R-HSA-6799566)
0.752
17
UniProt:P05556 ITGB1
2
ITGB1 [endosome membrane]
(R-HSA-9611157)
ITGB1 [plasma membrane]
(R-HSA-57596)
0.69
4
UniProt:O75954 TSN9
0.597
3
UniProt:P08195 SLC3A2
1
SLC3A2 [plasma membrane]
(R-HSA-352179)
0.597
3
UniProt:Q8NG11 TSPAN14
4
TSPAN14 [endoplasmic reticulum lumen]
(R-HSA-9010066)
TSPAN14 [specific granule membrane]
(R-HSA-6799708)
TSPAN14 [plasma membrane]
(R-HSA-6800467)
TSPAN14 [tertiary granule membrane]
(R-HSA-6800899)
0.597
4
UniProt:P02786 TFRC
5
TFRC(1-760) [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869124)
TFRC(1-760) [Golgi membrane]
(R-HSA-434330)
TFRC(1-760) [cytoplasmic vesicle membrane]
(R-HSA-434196)
TFRC(1-760) [plasma membrane]
(R-HSA-917983)
TFRC(1-760) [endosome membrane]
(R-HSA-8961829)
0.597
3
UniProt:P78536 ADAM17
6
ADAM17 [endoplasmic reticulum lumen]
(R-HSA-9662763)
ADAM17(215-827) [Golgi membrane]
(R-HSA-9662839)
ADAM17(1-214) [Golgi membrane]
(R-HSA-9662784)
ADAM17 [Golgi membrane]
(R-HSA-9662835)
ADAM17(215-827) [plasma membrane]
(R-HSA-9663048)
ADAM17 [plasma membrane]
(R-HSA-179878)
0.597
3
UniProt:P48509 CD151
2
CD151 [cytosol]
(R-HSA-446072)
CD151 [plasma membrane]
(R-HSA-913947)
0.597
7
UniProt:P23229 ITGA6
1
ITGA6(24-1130) [plasma membrane]
(R-HSA-204439)
0.597
3
UniProt:Q2M2E3 ODFP4
0.556
3
UniProt:P43121 MCAM
1
MCAM [plasma membrane]
(R-HSA-197922)
0.527
2
UniProt:Q8WWI5 SLC44A1
2
SLC44A1 [mitochondrial outer membrane]
(R-HSA-6798157)
SLC44A1 [plasma membrane]
(R-HSA-444456)
0.527
2
UniProt:P08473 MME
2
MME [plasma membrane]
(R-HSA-2022342)
MME [secretory granule membrane]
(R-HSA-6806156)
0.499
6
ChEBI:18348 1-PHOSPHATIDYL-1D-MYO-INOSITOL 4,5-BISPHOSPHATE
0.462
2
UniProt:O75054 IGSF3
0.462
2
UniProt:Q8NCG7 DAGLB
1
DAGLB [plasma membrane]
(R-HSA-426020)
0.462
2
UniProt:Q9NT68 TEN2
0.462
2
UniProt:P50895 BCAM
0.462
3
UniProt:P26006 ITGA3
1
ITGA3(33-1051) [plasma membrane]
(R-HSA-204441)
0.462
6
UniProt:Q9P273 TEN3
0.462
2
UniProt:Q12846 STX4
4
STX4 [phagocytic vesicle membrane]
(R-HSA-2029044)
STX4 [plasma membrane]
(R-HSA-181519)
STX4 [cytosol]
(R-HSA-114505)
p-STX4 [cytosol]
(R-HSA-114681)
0.462
2
UniProt:Q13277 STX3
1
STX3 [plasma membrane]
(R-HSA-449131)
0.462
2
ChEBI:16618 1-PHOSPHATIDYL-1D-MYO-INOSITOL 3,4,5-TRISPHOSPHATE
0.462
2
UniProt:P05026 ATP1B1
1
ATP1B1 [plasma membrane]
(R-HSA-375071)
0.462
2
UniProt:P36021 SLC16A2
1
SLC16A2 [plasma membrane]
(R-HSA-5216020)
0.462
2
ChEBI:16851 1-PHOSPHATIDYL-1D-MYO-INOSITOL 3,5-BISPHOSPHATE
0.462
2
UniProt:O95490 AGRL2
0.462
2
UniProt:P62079 TSPAN5
2
TSPAN5 [plasma membrane]
(R-HSA-9010031)
TSPAN5 [endoplasmic reticulum lumen]
(R-HSA-9010081)
0.462
5
UniProt:P17301 ITGA2
1
ITGA2 [plasma membrane]
(R-HSA-57562)
0.462
2
UniProt:P05023 ATP1A1
1
ATP1A1 [plasma membrane]
(R-HSA-936850)
0.462
2
UniProt:P54709 ATP1B3
1
ATP1B3 [plasma membrane]
(R-HSA-375073)
0.462
2
UniProt:O95858 TSPAN15
2
TSPAN15 [plasma membrane]
(R-HSA-9010043)
TSPAN15 [endoplasmic reticulum lumen]
(R-HSA-9010117)
0.462
2
UniProt:P09619 PDGFRB
3
p-11Y-PDGFRB [plasma membrane]
(R-HSA-8864039)
PDGFRB [plasma membrane]
(R-HSA-186767)
p-12Y-PDGFRB [plasma membrane]
(R-HSA-186803)
0.462
2
UniProt:P50281 MMP14
4
MMP14 [Golgi membrane]
(R-HSA-9858808)
MMP14(21-582) [Golgi lumen]
(R-HSA-1604689)
MMP14 [Golgi lumen]
(R-HSA-1604724)
MMP14 [plasma membrane]
(R-HSA-1442472)
0.462
2
UniProt:Q14118 DAG1
10
GalNAc-GlcNAc-Man6P-DAG1 [endoplasmic reticulum lumen]
(R-HSA-8931659)
GlcNAc,1,2-Man-DAG1 [Golgi lumen]
(R-HSA-5617087)
Man-DAG1 [Golgi lumen]
(R-HSA-8931888)
GalNAc-GlcNAc-Man-DAG1 [endoplasmic reticulum lumen]
(R-HSA-8931656)
GlcNAc-Man-DAG1 [endoplasmic reticulum lumen]
(R-HSA-8931673)
Man-DAG1 [endoplasmic reticulum lumen]
(R-HSA-5615647)
DAG1(30-653) [endoplasmic reticulum lumen]
(R-HSA-8931890)
DAG1(30-653) [cytosol]
(R-HSA-5615641)
DAG1(30-653) [extracellular region]
(R-HSA-2328152)
DAG1(654-895) [plasma membrane]
(R-HSA-2328154)
0.462
2
UniProt:P16070 CD44
2
CD44 [secretory granule membrane]
(R-HSA-6804776)
CD44 [plasma membrane]
(R-HSA-1031688)
0.462
2
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