Reactome | SUMO-K102-CRABP2 [nucleoplasm]

SUMO-K102-CRABP2 [nucleoplasm]

Stable Identifier

R-HSA-5334813

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Cellular retinoic acid-binding protein 2, RABP2_HUMAN

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External Reference Information

External Reference

UniProt:P29373 CRABP2

Gene Names

CRABP2

Chain

chain:1-138

Reference Genes

BioGPS Gene:1382 CRABP2

COSMIC (genes):CRABP2 CRABP2

CTD Gene:1382 CRABP2

dbSNP Gene:1382 CRABP2

ENSEMBL:ENSG00000143320 CRABP2

ENSEMBL_homo_sapiens_GENE:ENSG00000143320.9 CRABP2

HGNC:2339 CRABP2

KEGG Gene (Homo sapiens):1382 CRABP2

Monarch:1382 CRABP2

NCBI Gene:1382 CRABP2

OMIM:180231 CRABP2

UCSC:P29373 CRABP2

Reference Transcript

Other Identifiers

1057_at

11716609_a_at

11754057_x_at

11757595_x_at

1382

16694701

202575_PM_at

202575_at

2438461

2438462

2438463

2438464

2438465

2438467

2438468

2438469

2438470

2438471

41783_at

7921099

A_23_P115064

A_33_P3294826

GE496860

GO:0001972

GO:0005501

GO:0005504

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005737

GO:0005783

GO:0005829

GO:0006351

GO:0006355

GO:0006629

GO:0007165

GO:0008289

GO:0008544

GO:0015908

GO:0016918

GO:0019841

GO:0023052

GO:0030154

GO:0030332

GO:0035115

GO:0042573

GO:0043226

GO:0048672

GO:0048856

GO:0070062

HMNXSV003042015

ILMN_1690170

M97815_at

PH_hs_0010826

PH_hs_0032047

TC01003349.hg

g6382069_3p_at

Participates

as an output of

SUMO-CRABP2 dissociates from atRA:RAR:RXR (Homo sapiens)

as a component of

SUMO-K102-CRABP2:atRA [nucleoplasm] (Homo sapiens)

Other forms of this molecule

SUMO-K102-CRABP2 [cytosol]

Inferred To

crabp2 [nucleoplasm] (Xenopus tropicalis)

fabp [nucleoplasm] (Drosophila melanogaster)

SUMO-K102-CRABP2 [nucleoplasm] (Bos taurus)

SUMO-K102-CRABP2 [nucleoplasm] (Caenorhabditis elegans)

SUMO-K102-CRABP2 [nucleoplasm] (Gallus gallus)

SUMO-K102-CRABP2 [nucleoplasm] (Mus musculus)

SUMO-K102-CRABP2 [nucleoplasm] (Rattus norvegicus)

SUMO-K102-CRABP2 [nucleoplasm] (Sus scrofa)

crabp2a [nucleoplasm] (Danio rerio)

lbp-8 [nucleoplasm] (Caenorhabditis elegans)

CRABP2 [nucleoplasm] (Canis familiaris)

Homologues of SUMO-K102-CRABP2 [nucleoplasm] (Caenorhabditis elegans)

lbp-7 [nucleoplasm] (Caenorhabditis elegans)

Modified Residues

Name

sumoylated lysine at 102

Coordinate

102

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

XP_016855832.1, NP_001186652.1, NP_001869.1

Guide to Pharmacology - Targets

2530

OpenTargets

ENSG00000143320

GeneCards

P29373

HPA

ENSG00000143320-CRABP2

Ensembl

ENST00000621784, ENSG00000143320, ENSP00000357205, ENSP00000482841, ENSP00000357204, ENST00000368222, ENST00000368221

PRO

P29373

Pharos - Targets

P29373

HMDB Protein

HMDBP01927

PDB

6MQI, 6MOV, 1CBQ, 2FS7, 4YDA, 2FRS, 2CBS, 2G7B, 2FS6, 2G79, 1XCA, 3I17, 1BM5, 4I9S, 7AA0, 1BLR, 4I9R, 4YCH, 3D96, 4YGZ, 6Z2Z, 4YFQ, 6ZSW, 6HKR, 6MPK, 4M6S, 3CR6, 6ZSX, 7RY5, 6MQX, 6MR0, 4YFP, 6MQY, 6MOQ, 6MOR, 6MQZ, 4YGH, 2FR3, 1CBS, 4YGG, 3FA9, 4QGV, 3F9D, 6MOW, 6MOX, 4M7M, 5HZQ, 4YBP, 6MQJ, 3FA8, 3FA7, 3FEP, 6Z2U, 4YH0, 3FA6, 3D97, 4YKM, 6MQW, 4YFR, 4YKO, 7OXW, 3FEN, 2G78, 6NNY, 3FEL, 3D95, 6NNX, 7AA1, 6MOP, 3F8A, 7OXX, 4YCE, 3FEK, 3CWK, 4QGX, 5OGB, 6NOE, 4YDB, 3CBS, 4QGW, 4YBU

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8N6L0 KASH5			0.718	6
UniProt:P30281 CCND3	2	CCND3 [cytosol] (R-HSA-68333) CCND3 [nucleoplasm] (R-HSA-113835)	0.556	3
UniProt:P35609 ACTN2	3	ACTN2 [cytosol] (R-HSA-390562) ACTN2 [platelet alpha granule lumen] (R-HSA-349727) ACTN2 [extracellular region] (R-HSA-349725)	0.556	3
UniProt:Q8NFF5-2 FLAD1			0.556	3
UniProt:Q9HAW8 UGT1A10	1	UGT1A10 [endoplasmic reticulum membrane] (R-HSA-8933307)	0.527	2
UniProt:P43026 GDF5	1	GDF5(28-501) [extracellular region] (R-HSA-2396129)	0.527	2

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