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CAV1 [plasma membrane]
Stable Identifier
R-HSA-534994
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
caveolin-1
Icon
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
FOXO-mediated transcription (Homo sapiens)
FOXO-mediated transcription of cell cycle genes (Homo sapiens)
CAV1 gene expression is stimulated by FOXO1,FOXO3 (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of nitric oxide: NOS3 activation and regulation (Homo sapiens)
NOSTRIN mediated eNOS trafficking (Homo sapiens)
NOSTRIN mediated translocation of eNOS from plasma membrane (Homo sapiens)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 complex binds to Nostrin (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 (Homo sapiens)
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Homo sapiens)
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
eNOS activation (Homo sapiens)
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Homo sapiens)
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
HSP90 binds eNOS:Caveolin-1:CaM complex (Homo sapiens)
eNOS:Caveolin-1:CaM [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
eNOS associates with Caveolin-1 (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 complex binds to CaM (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1:CaM [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Extra-nuclear estrogen signaling (Homo sapiens)
PalmS-ESRs:CAVs translocate to plasma membrane (Homo sapiens)
CAVs [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by VEGF (Homo sapiens)
VEGFA-VEGFR2 Pathway (Homo sapiens)
VEGFR2 mediated vascular permeability (Homo sapiens)
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Homo sapiens)
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
HSP90 binds eNOS:Caveolin-1:CaM complex (Homo sapiens)
eNOS:Caveolin-1:CaM [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 complex binds to CaM (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1:CaM [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GDIs block activation of CDC42 (Homo sapiens)
CDC42 GDIs [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
CDC42:GDP:CDC42 GDIs [cytosol] (Homo sapiens)
CDC42 GDIs [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
CDC42 binds effectors at the plasma membrane (Homo sapiens)
CDC42 effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
CDC42:GTP:CDC42 effectors [plasma membrane] (Homo sapiens)
CDC42 effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 binds effectors at the plasma membrane (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RAC1:GTP:RAC1 effectors [plasma membrane] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RAC2 GTPase cycle (Homo sapiens)
RAC2 binds effectors at the plasma membrane (Homo sapiens)
RAC2 plasma membrane effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Homo sapiens)
RAC2 plasma membrane effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RAC3 GTPase cycle (Homo sapiens)
RAC3 binds effectors at the plasma membrane (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RAC3:GTP:RAC3 effectors [plasma membrane] (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA binds effectors at the plasma membrane (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOB GTPase cycle (Homo sapiens)
RHOB binds effectors at the plasma membrane (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOB:GTP:cytosolic RHOB effectors [plasma membrane] (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOC GTPase cycle (Homo sapiens)
RHOC binds effectors at the plasma membrane (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOC:GTP:RHOC effectors [plasma membrane] (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOD GTPase cycle (Homo sapiens)
RHOD binds effectors at the plasma membrane (Homo sapiens)
RHOD plasma membrane effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOD:GTP:RHOD plasma membrane effectors [plasma membrane] (Homo sapiens)
RHOD plasma membrane effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOF GTPase cycle (Homo sapiens)
RHOF binds effectors at the plasma membrane (Homo sapiens)
RHOF effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOF:GTP:RHOF effectors [plasma membrane] (Homo sapiens)
RHOF effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOG GTPase cycle (Homo sapiens)
RHOG binds effectors at the plasma membrane (Homo sapiens)
RHOG plasma membrane effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOG:GTP:RHOG plasma membrane effectors [plasma membrane] (Homo sapiens)
RHOG plasma membrane effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOH GTPase cycle (Homo sapiens)
RHOH binds effectors at the plasma membrane (Homo sapiens)
RHOH effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOH:GTP:RHOH effectors [plasma membrane] (Homo sapiens)
RHOH effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOJ GTPase cycle (Homo sapiens)
RHOJ binds effectors at the plasma membrane (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOJ:GTP:RHOJ effectors [plasma membrane] (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOQ GTPase cycle (Homo sapiens)
RHOQ binds effectors at the plasma membrane (Homo sapiens)
RHOQ effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RHOQ:GTP:RHOQ effectors [plasma membrane] (Homo sapiens)
RHOQ effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RND1 GTPase cycle (Homo sapiens)
RND1 binds effectors (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RND1:GTP:RND1 effectors [plasma membrane] (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RND2 GTPase cycle (Homo sapiens)
RND2 binds effectors (Homo sapiens)
RND2 effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RND2:GTP:RND2 effectors [plasma membrane] (Homo sapiens)
RND2 effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RND3 GTPase cycle (Homo sapiens)
RND3 binds effectors (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
RND3:GTP:RND3 effectors [plasma membrane] (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
Signaling by WNT (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Homo sapiens)
WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Homo sapiens)
WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [plasma membrane] (Homo sapiens)
CAV1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q03135 CAV1
Gene Names
CAV1, CAV
Chain
initiator methionine:, chain:2-178, initiator methionine:
Reference Genes
BioGPS Gene:857 CAV1
COSMIC (genes):CAV1 CAV1
CTD Gene:857 CAV1
dbSNP Gene:857 CAV1
ENSEMBL:ENSG00000105974 CAV1
ENSEMBL_homo_sapiens_GENE:ENSG00000105974.13 CAV1
HGNC:1527 CAV1
KEGG Gene (Homo sapiens):857 CAV1
Monarch:857 CAV1
NCBI Gene:857 CAV1
OMIM:601047 CAV1
UCSC:Q03135 CAV1
Reference Transcript
RefSeq:NM_001753.4 CAV1
Other Identifiers
11715584_a_at
11745715_a_at
11745716_s_at
11757013_x_at
17050578
203065_PM_s_at
203065_s_at
212097_PM_at
212097_at
3020304
3020305
3020306
3020307
3020308
3020309
3020310
3020311
3020320
3020321
3020322
3020323
3020324
36119_at
8135594
857
A_24_P12626
GE54670
GO:0000122
GO:0000139
GO:0000165
GO:0001525
GO:0001570
GO:0001666
GO:0001935
GO:0001937
GO:0001960
GO:0002026
GO:0002067
GO:0002080
GO:0002095
GO:0002376
GO:0002931
GO:0003012
GO:0003013
GO:0003057
GO:0005102
GO:0005113
GO:0005515
GO:0005768
GO:0005783
GO:0005789
GO:0005794
GO:0005811
GO:0005886
GO:0005901
GO:0005925
GO:0005929
GO:0005938
GO:0006351
GO:0006355
GO:0006629
GO:0006641
GO:0006809
GO:0006816
GO:0006874
GO:0006940
GO:0007155
GO:0007519
GO:0007595
GO:0008104
GO:0008142
GO:0008283
GO:0008285
GO:0008289
GO:0009267
GO:0009617
GO:0009968
GO:0010524
GO:0010608
GO:0010628
GO:0010875
GO:0012501
GO:0015031
GO:0015485
GO:0016020
GO:0016050
GO:0016192
GO:0016323
GO:0016324
GO:0016504
GO:0019065
GO:0019217
GO:0019221
GO:0019899
GO:0019901
GO:0019915
GO:0023052
GO:0030154
GO:0030163
GO:0030193
GO:0030198
GO:0030292
GO:0030301
GO:0030335
GO:0030514
GO:0030666
GO:0030674
GO:0030857
GO:0030879
GO:0031267
GO:0031295
GO:0031397
GO:0031398
GO:0031410
GO:0031623
GO:0031901
GO:0032507
GO:0032570
GO:0032991
GO:0033137
GO:0033138
GO:0033484
GO:0034141
GO:0034330
GO:0036211
GO:0038016
GO:0038166
GO:0042060
GO:0042310
GO:0042383
GO:0042532
GO:0042632
GO:0042802
GO:0043085
GO:0043123
GO:0043226
GO:0043409
GO:0043627
GO:0044325
GO:0044860
GO:0044877
GO:0045019
GO:0045121
GO:0045907
GO:0046426
GO:0046716
GO:0046982
GO:0048144
GO:0048147
GO:0048471
GO:0048550
GO:0048856
GO:0048870
GO:0050998
GO:0051117
GO:0051480
GO:0051592
GO:0051649
GO:0051899
GO:0052547
GO:0055065
GO:0055074
GO:0055085
GO:0060056
GO:0060070
GO:0060090
GO:0060355
GO:0060546
GO:0061024
GO:0061099
GO:0070320
GO:0070836
GO:0071218
GO:0071360
GO:0071375
GO:0071455
GO:0071560
GO:0071711
GO:0072584
GO:0086091
GO:0090090
GO:0097190
GO:0098542
GO:0098772
GO:0098903
GO:0098909
GO:0098911
GO:0120162
GO:0140311
GO:0140313
GO:1900027
GO:1900085
GO:1901380
GO:1901844
GO:1903361
GO:1903598
GO:1903609
GO:1904294
GO:2000535
GO:2000811
GO:2001238
GO:2001244
HMNXSV003015048
Hs.74034.1.S1_3p_at
ILMN_1687583
ILMN_2149226
PH_hs_0004233
TC07003339.hg
Z18951_at
g4580417_3p_s_at
Participates
as a candidate of
RND2 effectors [cytosol] (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
RHOQ effectors [cytosol] (Homo sapiens)
RHOH effectors [cytosol] (Homo sapiens)
CDC42 effectors [cytosol] (Homo sapiens)
RAC2 plasma membrane effectors [cytosol] (Homo sapiens)
RHOD plasma membrane effectors [cytosol] (Homo sapiens)
RHOF effectors [cytosol] (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
RHOG plasma membrane effectors [cytosol] (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
as a member of
CDC42 GDIs [cytosol] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
CAVs [plasma membrane] (Homo sapiens)
as an output of
CAV1 gene expression is stimulated by FOXO1,FOXO3 (Homo sapiens)
as a component of
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [plasma membrane] (Homo sapiens)
Other forms of this molecule
CAV1 [Golgi membrane]
CAV1 [early endosome membrane]
CAV1 [lipid droplet]
CAV1 [endocytic vesicle membrane]
Inferred To
cav1 [plasma membrane]
(Danio rerio)
cav1 [plasma membrane]
(Xenopus tropicalis)
Ghost homologue of CAV1 [plasma membrane]
(Dictyostelium discoideum)
Ghost homologue of CAV1 [plasma membrane]
(Drosophila melanogaster)
Ghost homologue of CAV1 [plasma membrane]
(Plasmodium falciparum)
Ghost homologue of CAV1 [plasma membrane]
(Schizosaccharomyces pombe)
cav-2 [plasma membrane]
(Caenorhabditis elegans)
Cav1 [plasma membrane]
(Mus musculus)
Cav1 [plasma membrane]
(Rattus norvegicus)
cav-1 [plasma membrane]
(Caenorhabditis elegans)
Homologues of CAV1 [plasma membrane]
(Caenorhabditis elegans)
CAV1 [plasma membrane]
(Bos taurus)
CAV1 [plasma membrane]
(Canis familiaris)
CAV1 [plasma membrane]
(Gallus gallus)
CAV1 [plasma membrane]
(Sus scrofa)
Cross References
RefSeq
NP_001744.2
OpenTargets
ENSG00000105974
HPA
ENSG00000105974-CAV1
GeneCards
Q03135
Ensembl
ENSG00000105974
,
ENSP00000384348
,
ENST00000393468
,
ENST00000393467
,
ENST00000341049
,
ENSP00000377110
,
ENSP00000377111
,
ENST00000405348
,
ENSP00000339191
PRO
Q03135
Pharos - Targets
Q03135
Orphanet
17896
PDB
7SC0
Interactors (53)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P00533 EGFR
20
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR A767_V769dup [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR N771_H773dup [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR K739_I744dup [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
0.813
7
UniProt:P51636 CAV2
2
CAV2 [plasma membrane]
(R-HSA-9021035)
CAV2 [Golgi membrane]
(R-HSA-9021032)
0.744
5
UniProt:P18031 PTPN1
2
PTPN1 [cytosol]
(R-HSA-210625)
PTPN1 [endosome membrane]
(R-HSA-9815895)
0.697
5
UniProt:P0DTD1-PRO_0000449624 REP
0.659
3
UniProt:Q969G5 CAVN3
0.649
11
UniProt:Q6NZI2 PTRF
2
PTRF [nucleoplasm]
(R-HSA-74981)
CAVIN1 [plasma membrane]
(R-HSA-9714278)
0.641
10
UniProt:P63000 RAC1
6
RAC1 [ficolin-1-rich granule membrane]
(R-HSA-6804802)
RAC1 [secretory granule membrane]
(R-HSA-6804770)
GGC-PalmC-RAC1 [plasma membrane]
(R-HSA-2316446)
RAC1 [endoplasmic reticulum membrane]
(R-HSA-5672076)
RAC1 [cytosol]
(R-HSA-442615)
RAC1 [plasma membrane]
(R-HSA-351141)
0.641
3
UniProt:P48995 TRPC1
1
TRPC1 [plasma membrane]
(R-HSA-2089937)
0.633
7
UniProt:Q16881 TXNRD1
1
TXNRD1 [cytosol]
(R-HSA-73531)
0.632
4
UniProt:O95810 CAVN2
0.602
6
UniProt:P41134 ID1
1
ID1 [nucleoplasm]
(R-HSA-2534101)
0.602
6
UniProt:P20936 RASA1
1
RASA1 [cytosol]
(R-HSA-186833)
0.59
2
UniProt:P48730-2 CSNK1D
0.556
3
UniProt:O75581 LRP6
8
p-T1479,S1490,T1493-LRP6 [plasma membrane]
(R-HSA-205884)
p-S1490-LRP6 [plasma membrane]
(R-HSA-206156)
LRP6 [early endosome membrane]
(R-HSA-5368481)
p-LRP6 [early endosome membrane]
(R-HSA-5368496)
LRP6N [extracellular region]
(R-HSA-5334021)
p-2S,S1490,2T-LRP6 [plasma membrane]
(R-HSA-1458894)
p-4S,3T,T1479,S1490,T1493-LRP6 [plasma membrane]
(R-HSA-1458895)
LRP6 [plasma membrane]
(R-HSA-206252)
0.556
3
UniProt:P05067 APP
20
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-713) [extracellular region]
(R-HSA-879340)
0.556
3
UniProt:P52735-1 VAV2
0.544
3
UniProt:Q03160
1
Grb7 [cytosol]
(R-MMU-204819)
0.532
3
UniProt:Q9GZM5 YIPF3
0.527
3
UniProt:Q96CS3 FAF2
3
FAF2 [cytosol]
(R-HSA-6781921)
FAF2 [extracellular region]
(R-HSA-6806183)
FAF2 [azurophil granule lumen]
(R-HSA-6799138)
0.527
2
UniProt:Q6ZMB5 T184A
0.527
2
UniProt:P28335 HTR2C
1
HTR2C [plasma membrane]
(R-HSA-390965)
0.527
2
UniProt:Q9H6D8 FNDC4
0.527
2
UniProt:Q8IVM8 S22A9
0.527
2
UniProt:Q9NY59 SMPD3
1
SMPD3 [plasma membrane]
(R-HSA-1606265)
0.527
2
UniProt:P56539 CAV3
1
CAV3 [plasma membrane]
(R-HSA-1368135)
0.527
2
UniProt:Q9H2J7 SLC6A15
1
SLC6A15 [plasma membrane]
(R-HSA-352060)
0.527
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.527
9
UniProt:P25103 TACR1
2
TACR1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869122)
TACR1 [plasma membrane]
(R-HSA-380103)
0.527
2
UniProt:P20309 CHRM3
1
CHRM3 [plasma membrane]
(R-HSA-399994)
0.527
2
UniProt:P30556 AGTR1
2
AGTR1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869071)
AGTR1 [plasma membrane]
(R-HSA-374247)
0.527
2
UniProt:Q8N695 SLC5A8
1
SLC5A8 [plasma membrane]
(R-HSA-429769)
0.527
2
UniProt:Q9H244 P2RY12
1
P2RY12 [plasma membrane]
(R-HSA-391959)
0.527
2
UniProt:Q99677 LPAR4
1
LPAR4 [plasma membrane]
(R-HSA-418020)
0.527
2
UniProt:P43657 LPAR6
1
LPAR6 [plasma membrane]
(R-HSA-417913)
0.527
2
UniProt:P19174 PLCG1
6
p-Y-PLCG1 [cytosol]
(R-HSA-9029082)
p-4Y-PLCG1 [plasma membrane]
(R-HSA-167679)
PLCG1 [cytosol]
(R-HSA-202320)
PLCG1 [plasma membrane]
(R-HSA-167682)
p-Y771,Y783,Y1254-PLCG1 [cytosol]
(R-HSA-202357)
p-Y771,Y783-PLCG1 [plasma membrane]
(R-HSA-1169084)
0.525
2
UniProt:O00194 RAB27B
5
GGC-RAB27B [melanosome membrane]
(R-HSA-8877280)
GGC-RAB27B [cytosol]
(R-HSA-8873786)
RAB27B [cytosol]
(R-HSA-8873706)
RAB27B [plasma membrane]
(R-HSA-8862952)
RAB27B [platelet dense granule membrane]
(R-HSA-8862955)
0.524
2
UniProt:P0DOE7 M
5
p-S95,T205-M [cytosol]
(R-RSY-9831678)
p-S95,T205-M [nucleoplasm]
(R-RSY-9831706)
M [nucleoplasm]
(R-RSY-9831711)
Nascent M [cytosol]
(R-RSY-9828672)
p-S95,T205-M [viral tegument]
(R-RSY-9836531)
0.524
2
UniProt:P01112 HRAS
20
HRAS Q61R [plasma membrane]
(R-HSA-6802458)
HRAS Q61L [plasma membrane]
(R-HSA-6802452)
HRAS Q61K [plasma membrane]
(R-HSA-6802442)
HRAS G13R [plasma membrane]
(R-HSA-6802368)
HRAS G12V [plasma membrane]
(R-HSA-6802350)
HRAS G12S [plasma membrane]
(R-HSA-6802343)
HRAS T58I [plasma membrane]
(R-HSA-9656014)
HRAS G13C [plasma membrane]
(R-HSA-9656008)
HRAS K117R [plasma membrane]
(R-HSA-9656010)
HRAS G13V [plasma membrane]
(R-HSA-9656579)
HRAS G13D [plasma membrane]
(R-HSA-9656572)
HRAS G13S [plasma membrane]
(R-HSA-9656574)
HRAS K117N [plasma membrane]
(R-HSA-9656603)
HRAS G12D [plasma membrane]
(R-HSA-9656564)
HRAS G12C [plasma membrane]
(R-HSA-9656561)
HRAS [plasma membrane]
(R-HSA-62717)
S-Farn-Me HRAS [plasma membrane]
(R-HSA-9665052)
S-Farn-Me PalmS HRAS [Golgi membrane]
(R-HSA-9647896)
S-Farn-Me HRAS [endoplasmic reticulum membrane]
(R-HSA-9647796)
S-Farn-HRAS [endoplasmic reticulum membrane]
(R-HSA-9647788)
0.508
2
UniProt:P10586 PTPRF
2
PTPRF [plasma membrane]
(R-HSA-6786486)
PTPRF [endosome membrane]
(R-HSA-9815889)
0.499
2
UniProt:P60484 PTEN
20
K48polyUb-PTEN [cytosol]
(R-HSA-8874327)
PolyUb-PTEN [nucleoplasm]
(R-HSA-6782515)
PTEN H93R [cytosol]
(R-HSA-2318524)
PTEN C124R [cytosol]
(R-HSA-2317439)
PTEN H93Y [cytosol]
(R-HSA-2318520)
PTEN R130G [cytosol]
(R-HSA-2317339)
PTEN H93D [cytosol]
(R-HSA-2318550)
PTEN R130L [cytosol]
(R-HSA-2317430)
PTEN H93A [cytosol]
(R-HSA-2318544)
PTEN G129E [cytosol]
(R-HSA-2318509)
PTEN S170N [cytosol]
(R-HSA-2318408)
PTEN R173P [cytosol]
(R-HSA-2317480)
PTEN R130Q [cytosol]
(R-HSA-2317416)
PTEN H93Q [cytosol]
(R-HSA-2318565)
PTEN G129R [cytosol]
(R-HSA-2318501)
PTEN H123Y [cytosol]
(R-HSA-2318469)
PTEN S170R [cytosol]
(R-HSA-2318437)
PTEN R173C [cytosol]
(R-HSA-2317478)
PTEN R173H [cytosol]
(R-HSA-2317473)
PTEN C124S [cytosol]
(R-HSA-2317379)
0.499
2
UniProt:Q15208 STK38
1
STK38 [cytosol]
(R-HSA-9715143)
0.499
3
UniProt:P52735 VAV2
2
VAV2 [cytosol]
(R-HSA-195012)
p-Y172-VAV2 [cytosol]
(R-HSA-442307)
0.499
2
UniProt:Q06124 PTPN11
4
p-Y542-PTPN11 [cytosol]
(R-HSA-1369081)
PTPN11 [nucleoplasm]
(R-HSA-8937745)
PTPN11 [cytosol]
(R-HSA-162563)
p-Y542,Y580-PTPN11 [cytosol]
(R-HSA-162573)
0.499
2
UniProt:P29350 PTPN6
5
PTPN6 [specific granule lumen]
(R-HSA-6799641)
PTPN6 [extracellular region]
(R-HSA-6806315)
PTPN6 [tertiary granule lumen]
(R-HSA-6800952)
PTPN6 [nucleoplasm]
(R-HSA-9008911)
PTPN6 [cytosol]
(R-HSA-197938)
0.499
2
UniProt:P0DTC5 M
10
M [plasma membrane]
(R-COV-9755780)
N-glycan M [virion membrane]
(R-COV-9694385)
M [virion membrane]
(R-COV-9694320)
M [endocytic vesicle membrane]
(R-COV-9694563)
N-glycan M [endocytic vesicle membrane]
(R-COV-9694738)
M [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9694439)
N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9694446)
M [endoplasmic reticulum membrane]
(R-COV-9767620)
nascent M [endoplasmic reticulum lumen]
(R-COV-9694279)
N-glycan M [endoplasmic reticulum membrane]
(R-COV-9694684)
0.483
2
UniProt:A0A0H3NFP4 A0A0H3NFP4
0.471
2
UniProt:O15118 NPC1
1
NPC1 [lysosomal membrane]
(R-HSA-5216153)
0.463
3
UniProt:P25445 FAS
1
FAS [plasma membrane]
(R-HSA-66248)
0.463
3
UniProt:Q07820 MCL1
1
MCL1 [cytosol]
(R-HSA-5661490)
0.463
3
UniProt:O70239
5
Axin1 [cytosol]
(R-RNO-4641133)
phospho-Axin1 [cytosol]
(R-RNO-3640864)
phospho-Axin1 [cytosol]
(R-RNO-3640841)
phospho-Axin1 [cytosol]
(R-RNO-206040)
Axin1 [cytosol]
(R-RNO-195249)
0.463
5
UniProt:Q12933 TRAF2
5
TRAF2 [nucleoplasm]
(R-HSA-8862199)
K63polyUb-TRAF2 [nucleoplasm]
(R-HSA-8862194)
K63polyUb-TRAF2 [cytosol]
(R-HSA-8862193)
PolyUb-TRAF2 [cytosol]
(R-HSA-6782848)
TRAF2 [cytosol]
(R-HSA-66370)
0.463
3
UniProt:P55957 BID
4
MYS-BID(62-195) [mitochondrial outer membrane]
(R-HSA-114266)
MYS-BID(62-195) [cytosol]
(R-HSA-141373)
BID(1-195) [cytosol]
(R-HSA-50825)
BID(62-195) [cytosol]
(R-HSA-139953)
0.463
3
UniProt:P22307 SCP2
4
SCP2(425-547) [peroxisomal matrix]
(R-HSA-9033522)
SCP2(1-424) [peroxisomal matrix]
(R-HSA-9033486)
SCP2 [cytosol]
(R-HSA-9033130)
SCP2 [peroxisomal matrix]
(R-HSA-2046067)
0.454
3
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