Reactome | HDGF [nucleoplasm]

HDGF [nucleoplasm]

Stable Identifier

R-HSA-535593

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Hepatoma-derived growth factor, HDGF_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P62807 H2BC4

Expand all

Cellular responses to stimuli (Homo sapiens)

- Cellular responses to stress (Homo sapiens)
  - Unfolded Protein Response (UPR) (Homo sapiens)
    - IRE1alpha activates chaperones (Homo sapiens)
      - XBP1(S) activates chaperone genes (Homo sapiens)
        
        Expression of HDGF (Homo sapiens)
        
        HDGF [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:P51858 HDGF

Gene Names

HDGF, HMG1L2

Chain

chain:1-240

Reference Genes

BioGPS Gene:3068 HDGF

COSMIC (genes):HDGF HDGF

CTD Gene:3068 HDGF

dbSNP Gene:3068 HDGF

ENSEMBL:ENSG00000143321 HDGF

HGNC:4856 HDGF

Monarch:3068 HDGF

NCBI Gene:3068 HDGF

OMIM:600339 HDGF

UCSC:P51858 HDGF

Reference Transcript

Other Identifiers

11737210_a_at

11737211_x_at

11739002_a_at

11739003_a_at

11739004_x_at

11745877_x_at

11749077_x_at

16694742

200896_PM_x_at

200896_x_at

216484_x_at

2438525

2438526

2438527

2438528

2438532

2438533

2438534

2438535

2438536

2438537

2438538

2438539

2438540

2438541

2438542

2438543

2438544

2438546

2438547

2438548

2438555

2438556

2438557

2438558

2438559

2438560

2438561

2438562

2438563

3068

36446_s_at

38779_r_at

7921133

A_24_P376707

A_33_P3235400

GE57099

GE85877

GO:0000122

GO:0000166

GO:0000978

GO:0001222

GO:0001227

GO:0003677

GO:0003714

GO:0003723

GO:0003779

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005737

GO:0006325

GO:0006338

GO:0006355

GO:0007165

GO:0008083

GO:0008092

GO:0008201

GO:0015631

GO:0017053

GO:0030312

GO:0031012

GO:0034504

GO:0043226

GO:0045944

GO:0048018

GO:0051781

GO:0060090

GO:0062023

GO:0098772

GO:0140110

HMNXSV003038838

HMNXSV003043903

HMNXSV003054603

ILMN_1765621

PH_hs_0004992

TC01003353.hg

g4758515_3p_s_at

Participates

as an output of

Expression of HDGF (Homo sapiens)

Cross References

ENSEMBL

ENST00000357325, ENSP00000349878, ENSP00000357192, ENST00000368209, ENST00000368206, ENSP00000357189

OpenTargets

ENSG00000143321

HPA

ENSG00000143321-HDGF

PRO

P51858

Pharos - Targets

P51858

GlyGen

P51858

HMDB Protein

HMDBP10733

PDB

1RI0, 2NLU

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P68431 HIST1H3G	20	2xAcK-HIST1H3A [nucleoplasm] (R-HSA-427507) Me1K5-H3C1 [nucleoplasm] (R-HSA-9677683) Ack-Me3K5-HIST1H3A [nucleoplasm] (R-HSA-4551293) AcK-Me3K10-HIST1H3A [nucleoplasm] (R-HSA-4551291) AcK-Me3K28-HIST1H3A [nucleoplasm] (R-HSA-4551292) Me2aR27-HIST1H3A [nucleoplasm] (R-HSA-5229052) Me2aR18-HIST1H3A [nucleoplasm] (R-HSA-5229062) Me2sR9-HIST1H3A [nucleoplasm] (R-HSA-5211328) Me2sR3-HIST1H3A [nucleoplasm] (R-HSA-5218935) AcK9,14-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8870893) AcK14,18,79-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871271) AcK9,14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871306) AcK14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871294) AcK9,14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8865596) AcK14,18-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871295) AcK14,18,79-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871288) AcK14,18-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871299) AcK14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871286) Me2K28-HIST1H3A [nucleoplasm] (R-HSA-4754193) MeK37-HIST1H3A [nucleoplasm] (R-HSA-4722135)	0.574	5
ChEBI:28304 HEPARIN			0.564	3
UniProt:Q96FN4 CPNE2			0.527	2
UniProt:Q13547 HDAC1	2	HDAC1 [nucleoplasm] (R-HSA-205021) monoSUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030)	0.512	4
UniProt:Q08945 SSRP1	1	SSRP1 [nucleoplasm] (R-HSA-65105)	0.512	4
UniProt:P17844 DDX5	4	DDX5 [nucleoplasm] (R-HSA-3900136) DDX5 [cytosol] (R-HSA-9682643) polySUMO2-K53-DDX5 [nucleoplasm] (R-HSA-3900186) monoSUMO1-K53-DDX5 [nucleoplasm] (R-HSA-3900041)	0.512	4
UniProt:Q07955 SRSF1	1	SRSF1 [nucleoplasm] (R-HSA-72031)	0.512	4
UniProt:P62807 H2BC4	9	HIST1H2BC [nucleoplasm] (R-HSA-181906) Ub-121-HIST1H2BC [nucleoplasm] (R-HSA-3364029) AcK21-HIST1H2BC [nucleoplasm] (R-HSA-4568626) AcK13-HIST1H2BC [nucleoplasm] (R-HSA-4568620) AcK6-HIST1H2BC [nucleoplasm] (R-HSA-4568623) AcK16-HIST1H2BC [nucleoplasm] (R-HSA-4568634) HIST1H2BC [extracellular region] (R-HSA-977564) AcK-HIST1H2BC [nucleoplasm] (R-HSA-4549246) Ub-HIST1H2BC [nucleoplasm] (R-HSA-6782552)	0.483	2
UniProt:Q9NR30 DDX21	1	DDX21 [nucleoplasm] (R-HSA-5250652)	0.483	2
UniProt:P78527 PRKDC	4	PRKDC [nucleoplasm] (R-HSA-62161) p-T2609,S2612,T2638,T2647-PRKDC [nucleoplasm] (R-HSA-76302) PRKDC [cytosol] (R-HSA-3134816) K48polyUb-PRKDC [cytosol] (R-HSA-8938766)	0.462	3
UniProt:P09874 PARP1	4	PARP1 [nucleoplasm] (R-HSA-201568) PAR-PARP1 [nucleoplasm] (R-HSA-5651713) monoSUMO1-K203,K486-PARP1 [nucleoplasm] (R-HSA-4551686) polySUMO2,3-K203,K486-PARP1 [nucleoplasm] (R-HSA-4551617)	0.462	3

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