p-AXL binds PI3K

Stable Identifier
R-HSA-5357479
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, cytosol
ReviewStatus
5/5
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p-AXL binds PI3K
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Axl with its two phosphorylated YxxM motifs associates with the p85 subunit of PI3K and mediates VEGFA mediated activation of PI3K/AKT pathway (Ruan & Kazlauskas, 2012).

Literature References
PubMed ID Title Journal Year
22327215 Axl is essential for VEGF-A-dependent activation of PI3K/Akt

Ruan, GX, Kazlauskas, A

EMBO J. 2012
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Orthologous Events
p-AXL binds PI3K (Bos taurus)
p-AXL binds PI3K (Canis familiaris)
p-AXL binds PI3K (Danio rerio)
p-AXL binds PI3K (Gallus gallus)
p-AXL binds PI3K (Mus musculus)
p-AXL binds PI3K (Rattus norvegicus)
p-AXL binds PI3K (Sus scrofa)
p-AXL binds PI3K (Xenopus tropicalis)
Authored
Garapati, P V  (2013-08-30)
Reviewed
Ballmer-Hofer, K  (2014-05-12)
Welsh, M  (2014-05-12)
Berger, P  (2014-05-12)
Created
Garapati, P V  (2014-03-21)
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