aminocarboxypropyl EEF2 [cytosol]

Stable Identifier
R-HSA-5358478
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Icon
aminocarboxypropyl EEF2 [cytosol] icon
aminocarboxypropyl EEF2 [cytosol] icon
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
23971743 The biosynthesis and biological function of diphthamide

Su, X, Lin, Z, Lin, H

Crit. Rev. Biochem. Mol. Biol. 2013
15485916 Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2

Leppla, SH, Liu, S, Kuremsky, JG, Fink, GR, Milne, GT

Mol. Cell. Biol. 2004
External Reference Information
External Reference
UniProt:P13639 EEF2
Gene Names
EEF2, EF2
Chain
initiator methionine:1, chain:2-858
Reference Genes
BioGPS Gene:1938 EEF2
COSMIC (genes):EEF2 EEF2
CTD Gene:1938 EEF2
dbSNP Gene:1938 EEF2
ENSEMBL:ENSG00000167658 EEF2
HGNC:3214 EEF2
KEGG Gene (Homo sapiens):1938 EEF2
Monarch:1938 EEF2
NCBI Gene:1938 EEF2
OMIM:130610 EEF2
UCSC:P13639 EEF2
Reference Transcript
Other Identifiers
0002760010
11715781_a_at
11715782_a_at
11715783_x_at
11748763_a_at
11748764_x_at
11751022_x_at
11757678_s_at
16867212
18671261
18671262
18671263
18671264
18671265
18671266
18671267
18671268
18671269
18671270
18671271
18671273
18671274
18671275
18671276
1938
200094_PM_s_at
200094_s_at
204102_s_at
36587_at
3846539
3846540
3846541
3846542
3846543
3846544
3846545
3846548
3846549
3846551
3846553
3846555
3846556
3846557
3846559
3846561
3846562
3846563
3846564
3846565
3846567
3846568
3846569
3846570
8032730
A_24_P87763
GE60349
GO:0000166
GO:0002039
GO:0002244
GO:0002376
GO:0002931
GO:0003009
GO:0003674
GO:0003723
GO:0003746
GO:0003924
GO:0005515
GO:0005525
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005737
GO:0005829
GO:0005840
GO:0005844
GO:0005886
GO:0006412
GO:0006414
GO:0006810
GO:0006950
GO:0007568
GO:0008092
GO:0008097
GO:0008135
GO:0008150
GO:0008283
GO:0009058
GO:0014009
GO:0016020
GO:0016192
GO:0016235
GO:0019843
GO:0019899
GO:0019901
GO:0030154
GO:0031410
GO:0032355
GO:0032991
GO:0034641
GO:0034774
GO:0034976
GO:0035914
GO:0042493
GO:0042542
GO:0042788
GO:0043022
GO:0043167
GO:0043226
GO:0043312
GO:0045121
GO:0045202
GO:0045296
GO:0045471
GO:0045727
GO:0048856
GO:0051015
GO:0051593
GO:0070062
GO:1904813
GO:1990416
GO:1990904
GO:2000767
HMNXSV003054355
ILMN_1738383
PH_hs_0004308
TC19001054.hg
X51466_at
g4503482_3p_a_at
Participates
as an output of
as an input of
Other forms of this molecule
EEF2 [ficolin-1-rich granule lumen]
EEF2 [extracellular region]
EEF2 [secretory granule lumen]
Me-diphthine EEF2 [cytosol]
nascent EEF2 [cytosol]
diphthine EEF2 [cytosol]
EEF2 [cytosol]
ADP-ribo-EEF2 [cytosol]
Me3K525-EEF2 [cytosol]
Inferred To
Homologues of aminocarboxypropyl EEF2 [cytosol] (Danio rerio)
eef2l2 [cytosol] (Danio rerio)
Eef2 [cytosol] (Mus musculus)
Eef2 [cytosol] (Rattus norvegicus)
eef-2 [cytosol] (Caenorhabditis elegans)
EFT2 [cytosol] (Saccharomyces cerevisiae)
EEF2 [cytosol] (Bos taurus)
EEF2 [cytosol] (Canis familiaris)
EEF2 [cytosol] (Gallus gallus)
EEF2 [cytosol] (Sus scrofa)
eft201 [cytosol] (Schizosaccharomyces pombe)
aminocarboxypropyl EEF2 [cytosol] (Plasmodium falciparum)
aminocarboxypropyl EEF2 [cytosol] (Xenopus tropicalis)
efbA [cytosol] (Dictyostelium discoideum)
eEF2 [cytosol] (Drosophila melanogaster)
eef2b [cytosol] (Danio rerio)
Modified Residues
Name
modified L-histidine residue (2-(3-amino-3-carboxypropyl)-L-histidine zwitterion residue) at 715
Coordinate
715
Modification
2-(3-amino-3-carboxypropyl)-L-histidine zwitterion residue
PsiMod Name
modified L-histidine residue
PsiMod Definition
A protein modification that modifies an L-histidine residue.
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
HPA
GeneCards
Ensembl
PRO
Pharos - Targets
GlyGen
Orphanet
HMDB Protein
PDB
Interactors (6)
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