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MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm]
Stable Identifier
R-HSA-5358524
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
MutSalpha:ADP:DNA containing 1-2 base mismatch
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
Mismatch Repair (Homo sapiens)
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) (Homo sapiens)
MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop (Homo sapiens)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm] (Homo sapiens)
MSH2:MSH6 exchanges ADP for ATP (Homo sapiens)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
11274057
hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci
Jiricny, J
,
Marra, G
,
Lettieri, T
,
Kleczkowska, HE
Genes Dev.
2001
Participants
components
DNA containing mismatch or 1-2 base IDL [nucleoplasm]
MSH2:MSH6:ADP [nucleoplasm]
(Homo sapiens)
Participates
as an input of
MSH2:MSH6 exchanges ADP for ATP (Homo sapiens)
as an output of
MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop (Homo sapiens)
Inferred To
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm]
(Bos taurus)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm]
(Caenorhabditis elegans)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm]
(Canis familiaris)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm]
(Danio rerio)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm]
(Dictyostelium discoideum)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm]
(Drosophila melanogaster)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm]
(Gallus gallus)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm]
(Mus musculus)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm]
(Plasmodium falciparum)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm]
(Rattus norvegicus)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm]
(Saccharomyces cerevisiae)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm]
(Schizosaccharomyces pombe)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm]
(Sus scrofa)
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