Reactome | ERLEC1 [endoplasmic reticulum quality control compartment]

ERLEC1 [endoplasmic reticulum quality control compartment]

Stable Identifier

R-HSA-5362354

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum quality control compartment

Synonyms

XTP3TPB, XTP3-B

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96DZ1 ERLEC1

Gene Names

ERLEC1, C2orf30, XTP3TPB, UNQ1878/PRO4321

Chain

signal peptide:1-33, chain:34-483

Reference Genes

BioGPS Gene:27248 ERLEC1

COSMIC (genes):ERLEC1 ERLEC1

CTD Gene:27248 ERLEC1

dbSNP Gene:27248 ERLEC1

ENSEMBL:ENSG00000068912 ERLEC1

HGNC:25222 ERLEC1

KEGG:hsa:27248 ERLEC1

Monarch:27248 ERLEC1

NCBI Gene:27248 ERLEC1

OMIM:611229 ERLEC1

UCSC:Q96DZ1 ERLEC1

Reference Transcript

Other Identifiers

11716643_s_at

11716644_a_at

11741872_a_at

16880063

224628_PM_at

224628_at

224630_PM_at

224630_at

244452_PM_at

244452_at

2482229

2482231

2482232

2482233

2482235

2482236

2482237

2482238

2482239

2482240

2482241

2482242

2482243

2482244

2482245

2482246

2482247

2482248

2482249

2482250

2482252

2482253

2482254

2482256

2482257

2482258

2482259

2482260

2482261

2482262

2482263

2482264

2482265

2482267

2482270

27248

46250_at

61414_at

8041967

A_14_P109145

A_14_P112400

A_14_P131004

A_19_P00804157

A_23_P39971

A_33_P3325018

A_33_P3325023

GE85819

GO:0005515

GO:0005783

GO:0005788

GO:0006886

GO:0030163

GO:0030246

GO:0030968

GO:0030970

GO:0036503

GO:0043226

GO:0044322

GO:0051082

GO:1904153

HMNXSV003006676

Hs.7100.0.A1_3p_at

Hs.7100.0.A2_3p_at

Hs.98364.0.A1_3p_at

ILMN_1724376

PH_hs_0020744

RNA147097|p0201_imsncRNA309

TC02000311.hg

Participates

as a member of

OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Homo sapiens)

Inferred To

Dmel\CG6766 [endoplasmic reticulum quality control compartment] (Drosophila melanogaster)

erlec1 [endoplasmic reticulum quality control compartment] (Danio rerio)

erlec1 [endoplasmic reticulum quality control compartment] (Xenopus tropicalis)

Erlec1 [endoplasmic reticulum quality control compartment] (Mus musculus)

Erlec1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)

ERLEC1 [endoplasmic reticulum quality control compartment] (Bos taurus)

ERLEC1 [endoplasmic reticulum quality control compartment] (Caenorhabditis elegans)

ERLEC1 [endoplasmic reticulum quality control compartment] (Canis familiaris)

ERLEC1 [endoplasmic reticulum quality control compartment] (Dictyostelium discoideum)

ERLEC1 [endoplasmic reticulum quality control compartment] (Gallus gallus)

ERLEC1 [endoplasmic reticulum quality control compartment] (Schizosaccharomyces pombe)

ERLEC1 [endoplasmic reticulum quality control compartment] (Sus scrofa)

Cross References

ENSEMBL

ENST00000185150, ENST00000405123, ENSP00000185150, ENSP00000367485, ENST00000378239, ENSP00000385629

OpenTargets

ENSG00000068912

HPA

ENSG00000068912-ERLEC1

PRO

Q96DZ1

Pharos - Targets

Q96DZ1

GlyGen

Q96DZ1

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P18850 ATF6	7	ATF6(1-380) [nucleoplasm] (R-HSA-381211) ATF6(420-670) [Golgi membrane] (R-HSA-420814) ATF6(380-419) [Golgi membrane] (R-HSA-420817) ATF6(1-380) [cytosol] (R-HSA-381075) ATF6(1-419) [Golgi membrane] (R-HSA-420815) ATF6 [Golgi membrane] (R-HSA-381000) ATF6 [endoplasmic reticulum membrane] (R-HSA-381222)	0.527	2
UniProt:Q9UBV2 SEL1L	1	SEL1L [endoplasmic reticulum membrane] (R-HSA-1911545)	0.527	6
UniProt:P0DTC8 8	2	8 [extracellular region] (R-COV-9755410) 8 [endoplasmic reticulum lumen] (R-COV-9727283)	0.527	2
UniProt:P04578 env	7	ENV [viral envelope] (R-HIV-173439) Surface protein gp120 [viral envelope] (R-HIV-171211) Transmembrane protein gp41 [viral envelope] (R-HIV-171195) Envelope glycoprotein gp160 [endoplasmic reticulum membrane] (R-HIV-189343) Glycosylated Envelope glycoprotein gp160 [Golgi membrane] (R-HIV-3149443) Transmembrane protein gp41 (P04578) [cytosol] (R-HIV-189359) Surface protein gp120 (P04578) [cytosol] (R-HIV-189269)	0.462	3