GPI-cleaved GPC5 [extracellular region]

Stable Identifier
R-HSA-5362356
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
GPC5, Glypican-5 component recommendedName: Secreted glypican-5 /component, GPC5_HUMAN
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P78333 GPC5
Gene Names
GPC5
Chain
signal peptide:1-24, chain:25-, chain:25-, propeptide:-572
Reference Genes
BioGPS Gene:2262 GPC5
COSMIC (genes):GPC5 GPC5
CTD Gene:2262 GPC5
dbSNP Gene:2262 GPC5
ENSEMBL:ENSG00000179399 GPC5
ENSEMBL_homo_sapiens_GENE:ENSG00000179399.16 GPC5
HGNC:4453 GPC5
KEGG Gene (Homo sapiens):2262 GPC5
Monarch:2262 GPC5
NCBI Gene:2262 GPC5
OMIM:602446 GPC5
UCSC:P78333 GPC5
Reference Transcript
Other Identifiers
11729726_at
11729727_at
16775785
207174_PM_at
207174_at
2262
3496410
3496411
3496412
3496413
3496417
3496445
3496452
3496454
3496469
3496480
3496528
3496529
3496530
3496531
3585647
3585660
3613117
3615141
3657682
3658096
36788_at
3688649
3688731
4038869
4039260
7969596
A_14_P100211
A_14_P110012
A_23_P112874
A_33_P3368855
GE58336
GO:0005515
GO:0005576
GO:0005764
GO:0005773
GO:0005794
GO:0005796
GO:0005886
GO:0009966
GO:0009986
GO:0016020
GO:0016477
GO:0023052
GO:0030312
GO:0031012
GO:0043202
GO:0043226
GO:0048870
GO:0062023
GO:0090263
GO:0098552
GO:1905475
HMNXSV003015846
ILMN_1688886
PH_hs_0026289
PH_hs_0028978
TC13000323.hg
U66033_at
g5360214_3p_at
Participates
as a component of
Other forms of this molecule
GPI-GPC5 [plasma membrane]
GPC5(25-?) [lysosomal lumen]
HS(6)-GPC5 [lysosomal lumen]
HS(6)-GPC5 [Golgi lumen]
HS(5)-GPC5 [Golgi lumen]
Heparan-GPC5 [Golgi lumen]
Heparan(1)-GPC5 [Golgi lumen]
Heparan(2)-GPC5 [Golgi lumen]
Heparan(3)-GPC5 [Golgi lumen]
Heparan(4)-GPC5 [Golgi lumen]
HS(1)-GPC5 [Golgi lumen]
HS(4)-GPC5 [plasma membrane]
HS(6)-GPC5 [plasma membrane]
HS(2)-GPC5 [plasma membrane]
HS(1)-GPC5 [plasma membrane]
HS(3)-GPC5 [plasma membrane]
HS(5)-GPC5 [plasma membrane]
XylS-GPC5(25-?) [Golgi lumen]
Gal-Xyl-GPC5 [Golgi lumen]
GPC5(25-?) [Golgi lumen]
Gal-Gal-Xyl-GPC5 [Golgi lumen]
GlcA-Gal-Gal-Xyl-GPC5 [Golgi lumen]
HS(3)-GPC5 [Golgi lumen]
HS(4)-GPC5 [Golgi lumen]
HS(2)-GPC5 [Golgi lumen]
Inferred To
A0A1D5NXW7 [extracellular region] (Gallus gallus)
gpc5a [extracellular region] (Danio rerio)
Gpc5 [extracellular region] (Mus musculus)
Gpc5 [extracellular region] (Rattus norvegicus)
dally [extracellular region] (Drosophila melanogaster)
GPC5 [extracellular region] (Bos taurus)
GPC5 [extracellular region] (Canis familiaris)
GPC5 [extracellular region] (Sus scrofa)
Modified Residues
Name
O-xylosyl-L-serine (ChEBI:63666) at unknown position
Modification
beta-D-IdoA-(1->4)-alpha-D-GlcNS6S-(1->4)-beta-D-IdoA2S-(1->4)-alpha-D-GlcNS3S-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group
PsiMod Name
O-xylosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-xylosylserine.
Name
O-xylosyl-L-serine (beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-GalNAc4S-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group) at unknown position
Modification
beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-GalNAc4S-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group
PsiMod Name
O-xylosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-xylosylserine.
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
Pharos - Targets
Orphanet
Interactors (4)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q96IK1-2 Q96IK12      0.556 3
 UniProt:Q8N488 RYBP  1 0.556 3
 UniProt:Q6P1L5 F117B      0.556 3
 UniProt:Q8TD91-2 MAGEC3      0.556 3
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