Reactome | MRPS27 [mitochondrial inner membrane]

MRPS27 [mitochondrial inner membrane]

Stable Identifier

R-HSA-5368214

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

28S ribosomal protein S27, mitochondrial, RT27_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q92552 MRPS27

Gene Names

MRPS27, KIAA0264

Chain

transit peptide:1-36, chain:37-414

Reference Genes

BioGPS Gene:23107 MRPS27

COSMIC (genes):MRPS27 MRPS27

CTD Gene:23107 MRPS27

dbSNP Gene:23107 MRPS27

ENSEMBL:ENSG00000113048 MRPS27

ENSEMBL_homo_sapiens_GENE:ENSG00000113048.19 MRPS27

HGNC:14512 MRPS27

KEGG Gene (Homo sapiens):23107 MRPS27

Monarch:23107 MRPS27

NCBI Gene:23107 MRPS27

OMIM:611989 MRPS27

UCSC:Q92552 MRPS27

Reference Transcript

Other Identifiers

11720639_a_at

11720640_x_at

11720641_x_at

11749237_a_at

16997068

212145_PM_at

212145_at

23107

2861949

2861951

2861953

2861954

2861955

2861956

2861957

2861958

2861961

2861962

2861965

2861969

2861971

2861973

2861974

2861987

2861988

2861994

2861997

2861998

2861999

39377_at

8112570

A_23_P133332

D87453_at

GE57407

GO:0000049

GO:0003723

GO:0005515

GO:0005634

GO:0005730

GO:0005737

GO:0005739

GO:0005743

GO:0005763

GO:0005840

GO:0006417

GO:0008283

GO:0019843

GO:0032543

GO:0043226

GO:0070131

GO:0097177

GO:0140053

GO:1990904

HMNXSV003030578

Hs.122669.0.S1_3p_at

ILMN_1711414

ILMN_2138435

PH_hs_0024259

TC05001463.hg

Participates

as a component of

28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)

Inferred To

mrps27 [mitochondrial inner membrane] (Danio rerio)

Mrps27 [mitochondrial inner membrane] (Mus musculus)

Mrps27 [mitochondrial inner membrane] (Rattus norvegicus)

mrps-27 [mitochondrial inner membrane] (Caenorhabditis elegans)

LD24471 [mitochondrial inner membrane] (Drosophila melanogaster)

MRPS27 [mitochondrial inner membrane] (Bos taurus)

MRPS27 [mitochondrial inner membrane] (Canis familiaris)

MRPS27 [mitochondrial inner membrane] (Gallus gallus)

MRPS27 [mitochondrial inner membrane] (Sus scrofa)

Cross References

RefSeq

NP_055899.2, NP_001273677.1

OpenTargets

ENSG00000113048

GeneCards

Q92552

HPA

ENSG00000113048-MRPS27

Ensembl

ENST00000513900, ENSG00000113048, ENSP00000426941, ENST00000261413, ENST00000694990, ENSP00000511631, ENST00000694989, ENSP00000511632, ENSP00000261413

PRO

Q92552

Pharos - Targets

Q92552

PDB

8OIS, 6ZSA, 7A5K, 7PO3, 7A5I, 6ZSB, 8OIR, 8ANY, 7PO2, 8CSS, 7OG4, 7PNX, 8CST, 6ZSC, 7P2E, 6VLZ, 7A5F, 6ZSD, 6NU2, 7QI6, 8CSQ, 7PO0, 6ZM5, 7PNZ, 8CSU, 7QI5, 6NU3, 7PNY, 6ZM6, 7QI4, 6VMI, 8CSP, 8CSR, 3J9M, 7PO1, 6ZS9, 6ZSG, 6ZSE, 7L08, 7A5G, 6RW5, 6RW4

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P62753 RPS6	4	RPS6 [nucleoplasm] (R-HSA-6790606) 3OHR147-RPS6 [cytosol] (R-HSA-9629876) p-5S-RPS6 [cytosol] (R-HSA-165727) RPS6 [cytosol] (R-HSA-72381)	0.569	3
UniProt:Q00839 HNRNPU	1	HNRNPU [nucleoplasm] (R-HSA-71953)	0.527	2
UniProt:P03372 ESR1	10	p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) p-S167-ESR1 [cytosol] (R-HSA-9841254) Me260-ESR1 [cytosol] (R-HSA-9632177) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) ESR1 [nucleoplasm] (R-HSA-446168) ESR1 [cytosol] (R-HSA-9020968)	0.527	3
UniProt:Q9H9Z2 LIN28A	1	LIN28A [cytosol] (R-HSA-500391)	0.527	2
UniProt:P67809 YBX1	5	p-S32,S36-YBX1 [nucleoplasm] (R-HSA-9733227) p-S32,S36-YBX1 [cytosol] (R-HSA-9736837) YBX1 [cytosol] (R-HSA-9736840) YBX1 [nucleoplasm] (R-HSA-72041) YBX1 [extracellular region] (R-HSA-9017791)	0.527	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.519	5