Reactome | MRPS17 [mitochondrial inner membrane]

MRPS17 [mitochondrial inner membrane]

Stable Identifier

R-HSA-5368241

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

28S ribosomal protein S17, mitochondrial, RT17_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y2R5 MRPS17

Gene Names

MRPS17, RPMS17, HSPC011

Chain

transit peptide:1-20, chain:21-130

Reference Genes

BioGPS Gene:51373 MRPS17

COSMIC (genes):MRPS17 MRPS17

CTD Gene:51373 MRPS17

dbSNP Gene:51373 MRPS17

ENSEMBL:ENSG00000239789 MRPS17

HGNC:14047 MRPS17

KEGG:hsa:51373 MRPS17

Monarch:51373 MRPS17

NCBI Gene:51373 MRPS17

OMIM:611980 MRPS17

UCSC:Q9Y2R5 MRPS17

Reference Transcript

RefSeq:NM_015969.2 MRPS17

Other Identifiers

11724780_x_at

11757672_s_at

11758920_at

11758921_x_at

17046249

218982_3p_s_at

218982_PM_s_at

218982_s_at

3003144

3003145

3003146

3003150

3003151

3003152

3988775

51373

62144_at

8132922

A_23_P258321

GE58631

GO:0003723

GO:0003735

GO:0005198

GO:0005515

GO:0005739

GO:0005743

GO:0005763

GO:0005840

GO:0006412

GO:0019843

GO:0032543

GO:0043226

GO:1990904

HMNXSV003024265

ILMN_1804851

PH_hs_0035423

TC07003325.hg

g7705424_3p_at

g7705424_3p_s_at

Participates

as a component of

28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)

Inferred To

mRpS17 [mitochondrial inner membrane] (Drosophila melanogaster)

mrps17 [mitochondrial inner membrane] (Danio rerio)

MRPS17 [mitochondrial inner membrane] (Bos taurus)

MRPS17 [mitochondrial inner membrane] (Canis familiaris)

MRPS17 [mitochondrial inner membrane] (Gallus gallus)

MRPS17 [mitochondrial inner membrane] (Sus scrofa)

Mrps17 [mitochondrial inner membrane] (Mus musculus)

Mrps17 [mitochondrial inner membrane] (Rattus norvegicus)

mrps-17 [mitochondrial inner membrane] (Caenorhabditis elegans)

Cross References

OpenTargets

ENSG00000239789

ENSEMBL

ENSP00000285298, ENST00000285298

HPA

ENSG00000239789-MRPS17

PRO

Q9Y2R5

Pharos - Targets

Q9Y2R5

PDB

7A5K, 8CSR, 8CSP, 6ZSA, 7PNX, 6ZSB, 6ZS9, 8CSQ, 7PO0, 8OIS, 8CSS, 6ZSG, 8OIR, 3J9M, 6ZSD, 6ZM6, 6ZSC, 6ZM5, 6VMI, 7PO1, 7PO3, 7P2E, 6VLZ, 8CSU, 7PNZ, 7L08, 7OG4, 7QI6, 7QI5, 7PO2, 7PNY, 6ZSE, 8CST, 6RW4, 7QI4, 6RW5, 7A5F, 6NU3, 6NU2, 8ANY, 7A5G, 7A5I

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-ESR1 [cytosol] (R-HSA-9632177) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.527	2
UniProt:Q92845 KIFAP3	3	KIFAP3 [cytosol] (R-HSA-984736) KIFAP3 [cilium] (R-HSA-5624882) KIFAP3 [ciliary tip] (R-HSA-5625382)	0.508	2

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