Reactome | MRPL46 [mitochondrial inner membrane]

MRPL46 [mitochondrial inner membrane]

Stable Identifier

R-HSA-5368247

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

39S ribosomal protein L46, mitochondrial, RM46_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9H2W6 MRPL46

Gene Names

MRPL46, C15orf4, LIECG2

Chain

transit peptide:1-, chain:-279

Reference Genes

BioGPS Gene:26589 MRPL46

COSMIC (genes):MRPL46 MRPL46

CTD Gene:26589 MRPL46

dbSNP Gene:26589 MRPL46

ENSEMBL:ENSG00000259494 MRPL46

ENSEMBL_homo_sapiens_GENE:ENSG00000259494.2 MRPL46

HGNC:1192 MRPL46

KEGG Gene (Homo sapiens):26589 MRPL46

Monarch:26589 MRPL46

NCBI Gene:26589 MRPL46

OMIM:611851 MRPL46

UCSC:Q9H2W6 MRPL46

Reference Transcript

RefSeq:NM_022163.3 MRPL46

Other Identifiers

11756687_a_at

16812982

219244_PM_s_at

219244_s_at

26589

3638049

3638050

3638059

3638063

3638066

3638067

7991209

91718_at

A_23_P37584

A_32_P209989

GE82670

GO:0003674

GO:0003735

GO:0005198

GO:0005634

GO:0005654

GO:0005739

GO:0005743

GO:0005762

GO:0005840

GO:0008150

GO:0030054

GO:0032543

GO:0043226

GO:0140053

GO:1990904

HMNXSV003020863

ILMN_1722838

PH_hs_0019802

PH_hs_0033283

TC15001816.hg

g11545915_3p_s_at

p33427

Participates

as a component of

39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)

Inferred To

mrpl-46 [mitochondrial inner membrane] (Caenorhabditis elegans)

Mrpl46 [mitochondrial inner membrane] (Mus musculus)

Mrpl46 [mitochondrial inner membrane] (Rattus norvegicus)

zgc:92810 [mitochondrial inner membrane] (Danio rerio)

MRPL46 [mitochondrial inner membrane] (Bos taurus)

MRPL46 [mitochondrial inner membrane] (Canis familiaris)

MRPL46 [mitochondrial inner membrane] (Gallus gallus)

MRPL46 [mitochondrial inner membrane] (Sus scrofa)

mRpL46 [mitochondrial inner membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_071446.2

OpenTargets

ENSG00000259494

HPA

ENSG00000259494-MRPL46

GeneCards

Q9H2W6

Ensembl

ENST00000312475, ENSG00000259494, ENSP00000312311

PRO

Q9H2W6

Pharos - Targets

Q9H2W6

PDB

7L08, 7A5F, 7O9M, 6ZSD, 6VLZ, 7A5G, 7OI9, 7QI6, 7PD3, 7OF7, 7OI8, 5OOM, 7QI5, 7ODT, 7OG4, 7O9K, 7OIE, 7QI4, 6ZSC, 6NU3, 7OF3, 7OIB, 7OF2, 6ZSA, 7ODR, 7ODS, 7A5H, 6ZSG, 7A5J, 8OIT, 7A5K, 8ANY, 8OIR, 6ZS9, 3J7Y, 6I9R, 6ZSE, 5OOL, 7OF6, 7OF4, 7PO4, 7L20, 7OI7, 7OF5, 7OIC, 7OIA, 6ZSB, 3J9M, 7OID, 7OF0, 6ZM5, 6VMI, 7A5I, 6ZM6, 6NU2

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O14561 NDUFAB1	4	Mal-PPANT-S112-NDUFAB1 [mitochondrial inner membrane] (R-HSA-8934586) PPANT-S112-NDUFAB1 [mitochondrial inner membrane] (R-HSA-8933545) octanoyl-S112-NDUFAB1 [mitochondrial inner membrane] (R-HSA-9857608) NDUFAB1 [mitochondrial inner membrane] (R-HSA-163925)	0.528	2

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