Reactome | MRPL49 [mitochondrial inner membrane]

MRPL49 [mitochondrial inner membrane]

Stable Identifier

R-HSA-5368260

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

39S ribosomal protein L49, mitochondrial, RM49_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q13405 MRPL49

Gene Names

MRPL49, C11orf4, NOF1, OK/SW-cl.67

Chain

chain:1-166

Reference Genes

BioGPS Gene:740 MRPL49

COSMIC (genes):MRPL49 MRPL49

CTD Gene:740 MRPL49

dbSNP Gene:740 MRPL49

ENSEMBL:ENSG00000149792 MRPL49

ENSEMBL_homo_sapiens_GENE:ENSG00000149792.9 MRPL49

HGNC:1176 MRPL49

KEGG Gene (Homo sapiens):740 MRPL49

Monarch:740 MRPL49

NCBI Gene:740 MRPL49

OMIM:606866 MRPL49

UCSC:Q13405 MRPL49

Reference Transcript

RefSeq:NM_004927.3 MRPL49

Other Identifiers

11726563_a_at

16726707

201717_PM_at

201717_at

3334920

3334921

3334926

3334928

3334929

3334930

3334931

3334932

3334934

36951_at

740

7941164

A_23_P138819

A_24_P201491

A_24_P232500

GE59127

GO:0003735

GO:0005198

GO:0005515

GO:0005739

GO:0005743

GO:0005761

GO:0005762

GO:0005840

GO:0006412

GO:0032543

GO:0043226

GO:0140053

GO:1990904

HMNXSV003055487

ILMN_1681324

PH_hs_0004379

TC11000617.hg

TC11002724.hg

U39400_at

g4826648_3p_at

Participates

as a component of

39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)

Inferred To

Mrpl49 [mitochondrial inner membrane] (Mus musculus)

Mrpl49 [mitochondrial inner membrane] (Rattus norvegicus)

mRpL49 [mitochondrial inner membrane] (Drosophila melanogaster)

mrpl49 [mitochondrial inner membrane] (Danio rerio)

MRPL49 [mitochondrial inner membrane] (Bos taurus)

MRPL49 [mitochondrial inner membrane] (Canis familiaris)

MRPL49 [mitochondrial inner membrane] (Sus scrofa)

mrpl-49 [mitochondrial inner membrane] (Caenorhabditis elegans)

Ghost homologue of MRPL49 [mitochondrial inner membrane] (Gallus gallus)

Cross References

RefSeq

NP_004918.1

OpenTargets

ENSG00000149792

GeneCards

Q13405

HPA

ENSG00000149792-MRPL49

Ensembl

ENST00000279242, ENST00000526319, ENSP00000434190, ENSP00000279242, ENSG00000149792

PRO

Q13405

Pharos - Targets

Q13405

PDB

8QSJ, 8OIR, 6NU3, 3J7Y, 8ANY, 7A5H, 3J9M, 6VMI, 6ZM6, 5OOM, 6ZSG, 7OG4, 7A5K, 5OOL, 7ODR, 7OF4, 7OI7, 7ODS, 6VLZ, 7OF5, 7OI8, 8PK0, 7ODT, 6ZSD, 7OI9, 7O9K, 6ZSC, 7L08, 6ZSB, 7O9M, 7OIA, 7A5F, 7QH6, 6ZSA, 7OIB, 7A5G, 8OIT, 6NU2, 7OF0, 7QH7, 6ZSE, 7OIC, 7A5I, 6ZS9, 7PO4, 7OF2, 7OID, 7A5J, 7OF3, 7OI6, 7OIE, 6I9R, 6ZM5, 7QI4, 7OF6, 7OF7, 7QI5, 7PD3, 7L20, 7QI6

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P16284 PECAM1	5	PECAM1 [platelet alpha granule membrane] (R-HSA-61489) PECAM1 [plasma membrane] (R-HSA-114686) PECAM1 [secretory granule membrane] (R-HSA-6804778) p-Y663,Y686-PECAM1(27-?) [plasma membrane] (R-HSA-210007) p-Y713-PECAM1 [plasma membrane] (R-HSA-9860772)	0.556	3
UniProt:P62241 RPS8	2	RPS8 [nucleoplasm] (R-HSA-6791203) RPS8 [cytosol] (R-HSA-72385)	0.527	3
UniProt:P67809 YBX1	5	p-S32,S36-YBX1 [nucleoplasm] (R-HSA-9733227) p-S32,S36-YBX1 [cytosol] (R-HSA-9736837) YBX1 [cytosol] (R-HSA-9736840) YBX1 [nucleoplasm] (R-HSA-72041) YBX1 [extracellular region] (R-HSA-9017791)	0.527	2