Reactome | CD3EAP [nucleoplasm]

CD3EAP [nucleoplasm]

Stable Identifier

R-HSA-5419289

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

DNA-directed RNA polymerase I subunit RPA34, RPA34_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O15446 POLR1G

Gene Names

POLR1G, ASE1, CAST, CD3EAP, PAF49

Chain

chain:1-510

Reference Genes

BioGPS Gene:10849 POLR1G

COSMIC (genes):CAST POLR1G

COSMIC (genes):CD3EAP POLR1G

CTD Gene:10849 POLR1G

dbSNP Gene:10849 POLR1G

ENSEMBL:ENSG00000117877 CD3EAP

HGNC:24219 POLR1G

Monarch:10849 POLR1G

NCBI Gene:10849 POLR1G

OMIM:107325 POLR1G

UCSC:O15446 POLR1G

Reference Transcript

Other Identifiers

10849

11739614_at

11739615_at

11739616_x_at

16863282

205264_PM_at

205264_at

3836247

3836248

3836249

3836250

3836251

3836252

3836254

3836255

3836256

3836257

3836258

3836259

3836260

3836261

3836262

3836263

8029688

A_14_P108742

A_23_P208310

A_24_P267452

GO:0000120

GO:0000428

GO:0001650

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005730

GO:0005736

GO:0005739

GO:0005829

GO:0006351

GO:0006360

GO:0006361

GO:0007169

GO:0009303

GO:0043226

HMNXSV003021607

ILMN_1747870

PH_hs_0028490

TC19000646.hg

g6912245_3p_at

Participates

as an input of

Assembly of RNA Polymerase I Holoenzyme (human) (Homo sapiens)

as a component of

RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)

Inferred To

Polr1g [nucleoplasm] (Mus musculus)

Polr1g [nucleoplasm] (Rattus norvegicus)

POLR1G [nucleoplasm] (Bos taurus)

POLR1G [nucleoplasm] (Canis familiaris)

POLR1G [nucleoplasm] (Sus scrofa)

Ghost homologue of CD3EAP [nucleoplasm] (Caenorhabditis elegans)

Ghost homologue of CD3EAP [nucleoplasm] (Dictyostelium discoideum)

Ghost homologue of CD3EAP [nucleoplasm] (Drosophila melanogaster)

Ghost homologue of CD3EAP [nucleoplasm] (Gallus gallus)

Ghost homologue of CD3EAP [nucleoplasm] (Plasmodium falciparum)

Ghost homologue of CD3EAP [nucleoplasm] (Saccharomyces cerevisiae)

Ghost homologue of CD3EAP [nucleoplasm] (Schizosaccharomyces pombe)

Ghost homologue of CD3EAP [nucleoplasm] (Xenopus tropicalis)

Cross References

ENSEMBL

ENST00000589804, ENSP00000310966, ENSP00000465099, ENST00000309424

OpenTargets

ENSG00000117877

HPA

ENSG00000117877-POLR1G

PRO

O15446

Pharos - Targets

O15446

GlyGen

O15446

PDB

7OB9, 7VBA, 7OBA, 8A43, 7OBB, 7VBC, 7VBB

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61218 POLR2F	2	POLR2F [cytosol] (R-HSA-1964441) POLR2F [nucleoplasm] (R-HSA-83714)	0.643	5
UniProt:P19388 POLR2E	2	POLR2E [cytosol] (R-HSA-1964438) POLR2E [nucleoplasm] (R-HSA-83713)	0.643	3
UniProt:O15160 POLR1C	2	POLR1C [cytosol] (R-HSA-1964454) POLR1C [nucleoplasm] (R-HSA-63498)	0.527	3
UniProt:O95602 POLR1A	1	POLR1A [nucleoplasm] (R-HSA-63494)	0.527	2