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POLR1E [nucleoplasm]
Stable Identifier
R-HSA-5419294
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
DNA-directed RNA polymerase I subunit RPA49, RPA49_HUMAN
Locations in the PathwayBrowser for interactor UniProt:P62875 POLR2L
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase I Transcription (Homo sapiens)
RNA Polymerase I Promoter Clearance (Homo sapiens)
RNA Polymerase I Transcription Initiation (Homo sapiens)
Assembly of RNA Polymerase I Holoenzyme (human) (Homo sapiens)
POLR1E [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9GZS1 POLR1E
Gene Names
POLR1E, PAF53, PRAF1
Chain
chain:1-419
Reference Genes
BioGPS Gene:64425 POLR1E
COSMIC (genes):POLR1E POLR1E
CTD Gene:64425 POLR1E
dbSNP Gene:64425 POLR1E
ENSEMBL:ENSG00000137054 POLR1E
HGNC:17631 POLR1E
Monarch:64425 POLR1E
NCBI Gene:64425 POLR1E
UCSC:Q9GZS1 POLR1E
Reference Transcript
RefSeq:NM_022490.2 POLR1E
RefSeq:NM_001282766.1 POLR1E
RefSeq:XM_005251547.2 POLR1E
Other Identifiers
11735123_x_at
11745730_a_at
11748672_x_at
17084990
218997_PM_at
218997_at
3168939
3168940
3168941
3168942
3168943
3168944
3168945
3168947
3168948
3168949
3168951
3168952
3168953
3168954
3168955
3168956
3168957
64425
8155268
A_23_P9458
GE62499
GO:0000428
GO:0001179
GO:0001188
GO:0001650
GO:0003677
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0005736
GO:0006351
GO:0006361
GO:0006362
GO:0042790
GO:0043226
GO:0065003
HMNXSV003055618
ILMN_1678934
ILMN_2110167
PH_hs_0002184
TC09002930.hg
g11968046_3p_at
Participates
as an input of
Assembly of RNA Polymerase I Holoenzyme (human) (Homo sapiens)
as a component of
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
Inferred To
Ghost homologue of POLR1E [nucleoplasm]
(Plasmodium falciparum)
Polr1E [nucleoplasm]
(Drosophila melanogaster)
RPA49 [nucleoplasm]
(Saccharomyces cerevisiae)
POLR1E [nucleoplasm]
(Bos taurus)
POLR1E [nucleoplasm]
(Canis familiaris)
POLR1E [nucleoplasm]
(Gallus gallus)
POLR1E [nucleoplasm]
(Sus scrofa)
Polr1e [nucleoplasm]
(Mus musculus)
Polr1e [nucleoplasm]
(Rattus norvegicus)
rpa49 [nucleoplasm]
(Schizosaccharomyces pombe)
rpoa-49 [nucleoplasm]
(Caenorhabditis elegans)
polr1e [nucleoplasm]
(Dictyostelium discoideum)
polr1e [nucleoplasm]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENSP00000367029
,
ENST00000377798
,
ENSP00000367023
,
ENST00000377792
OpenTargets
ENSG00000137054
HPA
ENSG00000137054-POLR1E
PRO
Q9GZS1
Pharos - Targets
Q9GZS1
HMDB Protein
HMDBP00756
PDB
8A43
,
7VBC
,
7OBB
,
7OB9
,
7VBB
,
7OBA
,
7VBA
Interactors (11)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P19388 POLR2E
2
POLR2E [cytosol]
(R-HSA-1964438)
POLR2E [nucleoplasm]
(R-HSA-83713)
0.744
5
UniProt:O15160 POLR1C
2
POLR1C [cytosol]
(R-HSA-1964454)
POLR1C [nucleoplasm]
(R-HSA-63498)
0.669
5
UniProt:Q15653 NFKBIB
3
p-S19,S23-Ub-NFKBIB [cytosol]
(R-HSA-1168571)
p-S19,S23-NFKBIB [cytosol]
(R-HSA-177670)
NFKBIB [cytosol]
(R-HSA-168132)
0.564
2
UniProt:Q92876 KLK6
0.556
3
UniProt:O95602 POLR1A
1
POLR1A [nucleoplasm]
(R-HSA-63494)
0.527
2
UniProt:P62875 POLR2L
2
POLR2L [cytosol]
(R-HSA-1964467)
POLR2L [nucleoplasm]
(R-HSA-83715)
0.527
3
UniProt:P61218 POLR2F
2
POLR2F [cytosol]
(R-HSA-1964441)
POLR2F [nucleoplasm]
(R-HSA-83714)
0.527
5
UniProt:Q9NYV6 RRN3
1
RRN3 [nucleoplasm]
(R-HSA-73714)
0.527
3
UniProt:P52294 KPNA1
2
KPNA1 [cytosol]
(R-HSA-180612)
KPNA1 [nucleoplasm]
(R-HSA-188865)
0.527
2
UniProt:Q3B726 POLR1F
1
TWISTNB [nucleoplasm]
(R-HSA-5419290)
0.527
2
UniProt:P52292 KPNA2
2
KPNA2 [cytosol]
(R-HSA-205976)
KPNA2 [nucleoplasm]
(R-HSA-206045)
0.527
2
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