Reactome | PLRG1 [nucleoplasm]

PLRG1 [nucleoplasm]

Stable Identifier

R-HSA-5420890

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Pleiotropic regulator 1, PLRG1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O43660 PLRG1

Gene Names

PLRG1

Chain

chain:1-514

Reference Genes

BioGPS Gene:5356 PLRG1

COSMIC (genes):PLRG1 PLRG1

CTD Gene:5356 PLRG1

dbSNP Gene:5356 PLRG1

ENSEMBL:ENSG00000171566 PLRG1

ENSEMBL_homo_sapiens_GENE:ENSG00000171566.12 PLRG1

HGNC:9089 PLRG1

KEGG Gene (Homo sapiens):5356 PLRG1

Monarch:5356 PLRG1

NCBI Gene:5356 PLRG1

OMIM:605961 PLRG1

UCSC:O43660 PLRG1

Reference Transcript

Other Identifiers

11732134_a_at

11750064_a_at

11759078_at

11759079_s_at

16980806

225194_PM_at

225194_at

227246_PM_at

227246_at

2790571

2790572

2790573

2790574

2790577

2790580

2790581

2790583

2790584

2790586

2790587

2790589

2790591

2790593

2790595

2790596

2790597

2790598

2790599

2790602

5356

53859_at

8103289

A_23_P84775

A_24_P268856

GE61608

GO:0000228

GO:0000278

GO:0000398

GO:0000974

GO:0001650

GO:0005515

GO:0005634

GO:0005635

GO:0005654

GO:0005662

GO:0005681

GO:0005694

GO:0005730

GO:0006397

GO:0008380

GO:0016071

GO:0016607

GO:0031965

GO:0034504

GO:0043226

GO:0071007

GO:0071013

GO:1900087

HMNXSV003018508

Hs.261285.0.A1_3p_at

Hs.261285.1.S1_3p_at

ILMN_1749634

PH_hs_0023229

TC04001660.hg

Participates

as a component of

PRP19-CDC5L complex [nucleoplasm] (Homo sapiens)

Inferred To

prp5 [nucleoplasm] (Schizosaccharomyces pombe)

PLRG1 [nucleoplasm] (Bos taurus)

PLRG1 [nucleoplasm] (Canis familiaris)

PLRG1 [nucleoplasm] (Gallus gallus)

PLRG1 [nucleoplasm] (Plasmodium falciparum)

plrg1 [nucleoplasm] (Danio rerio)

plrg1 [nucleoplasm] (Dictyostelium discoideum)

plrg1 [nucleoplasm] (Xenopus tropicalis)

Plrg1 [nucleoplasm] (Mus musculus)

Plrg1 [nucleoplasm] (Rattus norvegicus)

Tango4 [nucleoplasm] (Drosophila melanogaster)

Ghost homologue of PLRG1 [nucleoplasm] (Sus scrofa)

plrg-1 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001188493.1, NP_002660.1

OpenTargets

ENSG00000171566

GeneCards

O43660

HPA

ENSG00000171566-PLRG1

Ensembl

ENSP00000303191, ENSP00000424417, ENST00000499023, ENSG00000171566, ENST00000302078

PRO

O43660

Pharos - Targets

O43660

PDB

7ABF, 5XJC, 7DH6, 6ICZ, 6ID0, 6ID1, 5Z56, 5YZG, 8CH6, 5Z57, 6ZYM, 4YVD, 7DVQ, 7ABI, 5Z58, 5MQF, 7ABG, 8C6J, 6FF4, 7QTT, 7W5B, 7W5A, 7W59, 7AAV, 6QDV, 6FF7

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P52272 HNRNPM	1	HNRNPM [nucleoplasm] (R-HSA-71949)	0.613	5
UniProt:Q9CSN1 Snw1	1	Snw1 [nucleoplasm] (R-MMU-2065315)	0.564	2
UniProt:O75533 SF3B1	1	SF3B1 [nucleoplasm] (R-HSA-71968)	0.547	2