RXRA:PPARD binds FABP5:atRA

Stable Identifier
R-HSA-5422942
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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RXRA:PPARD binds FABP5:atRA
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In the nucleus, all-trans-retinoic acid (atRA), bounds to epidermal fatty acid-binding protein (FABP5), is transferred to the heterodimeric complex of retinoic acid receptor alpha RXRA) and peroxisome proliferator-activated receptor delta (PPARD). When bound to PPARD, atRA can significantly increase the expression of proteins involved in fatty acid oxidation and energy metabolism via its induction of PPARD (Wolf 2010, Amengual et al. 2012, Noy 2013).
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Orthologous Events
RXRA:PPARD binds FABP5:atRA (Bos taurus)
RXRA:PPARD binds FABP5:atRA (Caenorhabditis elegans)
RXRA:PPARD binds FABP5:atRA (Canis familiaris)
RXRA:PPARD binds FABP5:atRA (Gallus gallus)
RXRA:PPARD binds FABP5:atRA (Mus musculus)
RXRA:PPARD binds FABP5:atRA (Rattus norvegicus)
RXRA:PPARD binds FABP5:atRA (Sus scrofa)
RXRA:PPARD binds FABP5:atRA (Xenopus tropicalis)
Authored
Jassal, B  (2014-05-07)
Reviewed
Duester, G  (2014-07-28)
Napoli, JL  (2014-09-01)
Created
Jassal, B  (2014-05-07)
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