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TAOK3 [cytosol]
Stable Identifier
R-HSA-5423594
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Serine/threonine-protein kinase TAO3 ecNumber2.7.11.1/ecNumber, TAOK3_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 binds effectors at the plasma membrane (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
TAOK3 [cytosol] (Homo sapiens)
RAC1:GTP:RAC1 effectors [plasma membrane] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
TAOK3 [cytosol] (Homo sapiens)
RAC2 GTPase cycle (Homo sapiens)
RAC2 binds effectors at the plasma membrane (Homo sapiens)
RAC2 plasma membrane effectors [cytosol] (Homo sapiens)
TAOK3 [cytosol] (Homo sapiens)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Homo sapiens)
RAC2 plasma membrane effectors [cytosol] (Homo sapiens)
TAOK3 [cytosol] (Homo sapiens)
RAC3 GTPase cycle (Homo sapiens)
RAC3 binds effectors at the plasma membrane (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
TAOK3 [cytosol] (Homo sapiens)
RAC3:GTP:RAC3 effectors [plasma membrane] (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
TAOK3 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H2K8 TAOK3
Gene Names
TAOK3, DPK, JIK, KDS, MAP3K18
Chain
chain:1-898
Reference Genes
BioGPS Gene:51347 TAOK3
COSMIC (genes):TAOK3 TAOK3
CTD Gene:51347 TAOK3
dbSNP Gene:51347 TAOK3
ENSEMBL:ENSG00000135090 TAOK3
ENSEMBL_homo_sapiens_GENE:ENSG00000135090.14 TAOK3
HGNC:18133 TAOK3
KEGG Gene (Homo sapiens):51347 TAOK3
Monarch:51347 TAOK3
NCBI Gene:51347 TAOK3
OMIM:616711 TAOK3
UCSC:Q9H2K8 TAOK3
Reference Transcript
RefSeq:NM_001346489.1 TAOK3
RefSeq:NM_001346488.1 TAOK3
RefSeq:NM_016281.3 TAOK3
Other Identifiers
11733258_a_at
11733259_s_at
16770961
220761_PM_s_at
220761_s_at
3473803
3473804
3473805
3473806
3473807
3473808
3473811
3473817
3473821
3473823
3473824
3473825
3473826
3473827
3473836
3473838
3473839
3473840
3473845
3473846
3473848
3473849
3473852
3473853
3473854
3473855
3473856
3473863
3473864
3473865
3473883
3473887
3473888
3473902
41646_at
51347
67219_at
73951_at
7966851
A_23_P2203
A_24_P104174
A_33_P3346102
GE58717
GO:0000165
GO:0000166
GO:0000278
GO:0003824
GO:0004672
GO:0004674
GO:0004860
GO:0005515
GO:0005524
GO:0005737
GO:0005886
GO:0006281
GO:0006468
GO:0006974
GO:0007095
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0030154
GO:0032874
GO:0036211
GO:0043408
GO:0043507
GO:0046329
GO:0046330
GO:0046777
GO:0048812
GO:0048856
GO:0098772
GO:0106310
GO:0140096
HMNXSV003034963
HMNXSV003037670
PH_hs_0001129
TC12002018.hg
g6708149_3p_at
g7705559_3p_a_at
Participates
as a candidate of
RAC2 plasma membrane effectors [cytosol] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
Inferred To
TAOK3 [cytosol]
(Bos taurus)
TAOK3 [cytosol]
(Caenorhabditis elegans)
TAOK3 [cytosol]
(Canis familiaris)
TAOK3 [cytosol]
(Dictyostelium discoideum)
TAOK3 [cytosol]
(Gallus gallus)
TAOK3 [cytosol]
(Mus musculus)
TAOK3 [cytosol]
(Rattus norvegicus)
TAOK3 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_001333418.1
,
NP_057365.3
,
NP_001333417.1
ZINC - World Drugs
TAOK3_HUMAN
Guide to Pharmacology - Targets
2235
OpenTargets
ENSG00000135090
ZINC - FDA approved
TAOK3_HUMAN
ZINC - Substances
TAOK3_HUMAN
ZINC target
Q9H2K8
ZINC - Biogenic
TAOK3_HUMAN
PRO
Q9H2K8
PDB
6BDN
ZINC - Investigational
TAOK3_HUMAN
HPA
ENSG00000135090-TAOK3
GeneCards
Q9H2K8
Ensembl
ENST00000419821
,
ENST00000392533
,
ENSP00000416374
,
ENSG00000135090
,
ENSP00000376317
Pharos - Targets
Q9H2K8
ZINC - Predictions - Purchasable
TAOK3_HUMAN
HMDB Protein
HMDBP09480
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
UniProt:Q12933 TRAF2
5
TRAF2 [nucleoplasm]
(R-HSA-8862199)
K63polyUb-TRAF2 [nucleoplasm]
(R-HSA-8862194)
K63polyUb-TRAF2 [cytosol]
(R-HSA-8862193)
PolyUb-TRAF2 [cytosol]
(R-HSA-6782848)
TRAF2 [cytosol]
(R-HSA-66370)
0.524
2
UniProt:O75460 ERN1
2
p-S724-ERN1 [endoplasmic reticulum membrane]
(R-HSA-381029)
ERN1 [endoplasmic reticulum membrane]
(R-HSA-381076)
0.508
3
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