Formation of MSH2:MSH3 Complex

Stable Identifier
R-HSA-5444511
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Formation of MSH2:MSH3 Complex
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
MSH2 is homologous to the E. coli MutS gene and is involved in DNA mismatch repair. Repair is initiated with the activation of the MSH2:MSH3 complex.
Literature References
PubMed ID Title Journal Year
8128251 Mutation of a mutL homolog in hereditary colon cancer

Wei, YF, Fleischmann, RD, Papadopoulos, N, Rosen, CA, Haseltine, WA, Nicolaides, NC, Adams, MD, Carter, KC, Ruben, SM, Fraser, CM

Science 1994
Participants
Input
Output
Participates
as an event of
Orthologous Events
Formation of MSH2:MSH3 Complex (Bos taurus)
Formation of MSH2:MSH3 Complex (Canis familiaris)
Formation of MSH2:MSH3 Complex (Dictyostelium discoideum)
Formation of MSH2:MSH3 Complex (Gallus gallus)
Formation of MSH2:MSH3 Complex (Mus musculus)
Formation of MSH2:MSH3 Complex (Saccharomyces cerevisiae)
Formation of MSH2:MSH3 Complex (Schizosaccharomyces pombe)
Formation of MSH2:MSH3 Complex (Sus scrofa)
Authored
Gillespie, ME  (2014-05-09)
Reviewed
Edelbrock, MA  (2014-05-23)
Created
Gillespie, ME  (2014-05-14)
Cite Us!