FASN [cytosol]

Stable Identifier
R-HSA-54659
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
O-phosphopantetheine-L-ser-FASN, Fatty acid synthase, FAS
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
7567999 Human fatty acid synthase: properties and molecular cloning

Jayakumar, A, Wakil, SJ, Huang, WY, Hsu, M, Chirala, SS, al-Feel, W, Abu-Elheiga, L, Tai, MH

Proc Natl Acad Sci U S A 1995
External Reference Information
External Reference
UniProt:P49327 FASN
Gene Names
FASN, FAS
Chain
chain:1-2511
Reference Genes
BioGPS Gene:2194 FASN
COSMIC (genes):FASN FASN
CTD Gene:2194 FASN
dbSNP Gene:2194 FASN
ENSEMBL:ENSG00000169710 FASN
ENSEMBL_homo_sapiens_GENE:ENSG00000169710.9 FASN
HGNC:3594 FASN
KEGG Gene (Homo sapiens):2194 FASN
Monarch:2194 FASN
NCBI Gene:2194 FASN
OMIM:600212 FASN
UCSC:P49327 FASN
Reference Transcript
Other Identifiers
11743314_a_at
16850107
212218_PM_s_at
212218_s_at
217006_PM_x_at
217006_x_at
2194
2802091
3774634
3774636
3774637
3774639
3774641
3774642
3774643
3774645
3774647
3774649
3774650
3774651
3774652
3774653
3774655
3774657
3774658
3774659
3774660
3774661
3774662
3774663
3774664
3774666
3774667
3774668
3774669
3774670
3774671
3774672
3774673
3774674
3774677
3774678
3774679
3774680
3774681
3774682
3774683
3774684
3774685
3774686
3774687
3774688
3774689
3774690
3774693
3774694
3774698
38429_at
8019392
A_23_P44132
A_33_P3329344
GE59061
GO:0001649
GO:0002068
GO:0003723
GO:0003824
GO:0004312
GO:0004313
GO:0004314
GO:0004315
GO:0004316
GO:0004317
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005794
GO:0005829
GO:0005886
GO:0006629
GO:0006631
GO:0006633
GO:0006954
GO:0008152
GO:0008610
GO:0008611
GO:0008659
GO:0008693
GO:0009058
GO:0009888
GO:0016020
GO:0016295
GO:0016296
GO:0016297
GO:0016419
GO:0016491
GO:0016740
GO:0016746
GO:0016787
GO:0016829
GO:0019171
GO:0030154
GO:0030223
GO:0030224
GO:0030879
GO:0031177
GO:0031410
GO:0042470
GO:0042587
GO:0043226
GO:0044788
GO:0045296
GO:0047117
GO:0047450
GO:0047451
GO:0048856
GO:0070062
GO:0071353
GO:0090557
HMNXSV003010470
Hs.11050.2.A2_3p_s_at
Hs.83190.1.S1_3p_a_at
ILMN_1784871
PH_hs_0004753
S80437_s_at
TC17001973.hg
Participates
as an output of
as an input of
as a component of
Other forms of this molecule
FASN [cytosol]
decanoyl-FASN [cytosol]
Inferred To
phospho-stlA [cytosol] (Dictyostelium discoideum)
phospho-FASN1 [cytosol] (Drosophila melanogaster)
phospho-fasn [cytosol] (Xenopus tropicalis)
phospho-fasn-1 [cytosol] (Caenorhabditis elegans)
phospho-pks17 [cytosol] (Dictyostelium discoideum)
Ghost homologue of FASN [cytosol] (Danio rerio)
Homologues of FASN [cytosol] (Dictyostelium discoideum)
phospho-pks16 [cytosol] (Dictyostelium discoideum)
phospho-FASN [cytosol] (Bos taurus)
phospho-FASN [cytosol] (Canis familiaris)
phospho-FASN [cytosol] (Gallus gallus)
phospho-FASN [cytosol] (Mus musculus)
phospho-FASN [cytosol] (Rattus norvegicus)
phospho-FASN [cytosol] (Sus scrofa)
Modified Residues
Name
O-phosphopantetheine-L-serine at 2156
Coordinate
2156
PsiMod Name
O-phosphopantetheine-L-serine [MOD:00159]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phosphopantetheine-L-serine.
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
PDB
ZINC - Metabolites
GeneCards
HPA
Ensembl
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (12)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P42858 HTT  1 0.666 13
 UniProt:P13569 CFTR  17 0.615 11
 UniProt:Q99IB8-PRO_0000045603      0.556 6
 UniProt:Q8TBB1 LNX1  1 0.556 3
 IntAct:EBI-25865403 EHD27213144      0.556 3
 UniProt:Q15848 ADIPOQ  1 0.556 3
 UniProt:P31749 AKT1  13 0.547 2
 UniProt:Q8IV20 LACC1      0.539 8
 UniProt:Q13418 ILK  1 0.527 2
 UniProt:Q8N8N7 PTGR2  1 0.527 3
 UniProt:P10636-8 MAPT  3 0.527 4
 UniProt:Q16665 HIF1A  7 0.463 4
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