Reactome | MED16 [nucleoplasm]

MED16 [nucleoplasm]

Stable Identifier

R-HSA-556802

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Mediator of RNA polymerase II transcription subunit 16, MED16_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q9NX70 MED29

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External Reference Information

External Reference

UniProt:Q9Y2X0 MED16

Gene Names

MED16, DRIP92, THRAP5

Chain

chain:1-877

Reference Genes

BioGPS Gene:10025 MED16

COSMIC (genes):MED16 MED16

CTD Gene:10025 MED16

dbSNP Gene:10025 MED16

ENSEMBL:ENSG00000175221 MED16

HGNC:17556 MED16

KEGG:hsa:10025 MED16

Monarch:10025 MED16

NCBI Gene:10025 MED16

OMIM:604062 MED16

UCSC:Q9Y2X0 MED16

Reference Transcript

RefSeq:NM_005481.2 MED16

Other Identifiers

10025

11744547_x_at

11745655_x_at

11753464_x_at

11753523_x_at

11753643_x_at

11753748_x_at

11755741_x_at

11756057_a_at

16866514

221418_PM_s_at

221418_s_at

221544_PM_s_at

221544_s_at

221545_PM_x_at

221545_x_at

221938_PM_x_at

221938_x_at

3844823

3844824

3844825

3844826

3844827

3844828

3844829

3844830

3844832

3844833

3844834

3844837

3844838

3844839

3844840

3844841

3844842

3844844

3844845

3844846

3844847

3844848

3844849

3844850

3844851

3844852

3844853

3844854

43544_PM_at

43544_at

45754_at

8032106

A_23_P56170

GE58368

GO:0003713

GO:0005515

GO:0005634

GO:0005654

GO:0006351

GO:0006355

GO:0006357

GO:0006366

GO:0016020

GO:0016592

GO:0032968

GO:0042809

GO:0045893

GO:0046966

GO:0051123

GO:0060261

GO:0065003

GO:0070847

HMNXSV003017075

Hs.31659.0.S1_3p_a_at

ILMN_1719185

ILMN_1730307

ILMN_1790782

ILMN_1800451

TC19000991.hg

TC19002278.hg

TC19002279.hg

g4885646_3p_s_at

p26736

Participates

as a component of

as an input of

Inferred To

Med16 [nucleoplasm] (Rattus norvegicus)

med16 [nucleoplasm] (Danio rerio)

MED16 [nucleoplasm] (Bos taurus)

MED16 [nucleoplasm] (Canis familiaris)

MED16 [nucleoplasm] (Drosophila melanogaster)

MED16 [nucleoplasm] (Gallus gallus)

MED16 [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_005472.2

OpenTargets

ENSG00000175221

ENSEMBL

ENSP00000379153, ENSP00000325612, ENSG00000175221, ENST00000312090, ENST00000395808, ENSP00000308528, ENST00000325464

HPA

ENSG00000175221-MED16

GeneCards

MED16

PRO

Q9Y2X0

Pharos - Targets

Q9Y2X0

GlyGen

Q9Y2X0

PDB

8GXS, 7ENJ, 8GXQ, 7ENA, 7ENC, 7EMF, 7LBM, 8T9D, 8TRH, 8TQW

Interactors (23)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BTT4 MED10	1	MED10 [nucleoplasm] (R-HSA-212410)	0.825	7
UniProt:P49336 CDK8	1	CDK8 [nucleoplasm] (R-HSA-212440)	0.802	8
UniProt:A0JLT2 MED19	1	MED19 [nucleoplasm] (R-HSA-556819)	0.788	6
UniProt:Q9BWU1 CDK19	1	CDK19 [nucleoplasm] (R-HSA-556782)	0.744	6
UniProt:Q9NPJ6 MED4	1	MED4 [nucleoplasm] (R-HSA-350263)	0.725	6
UniProt:Q13503 MED21	1	MED21 [nucleoplasm] (R-HSA-212456)	0.725	6
UniProt:Q9ULK4 MED23	1	MED23 [nucleoplasm] (R-HSA-556823)	0.695	5
UniProt:Q71SY5 MED25	1	MED25 [nucleoplasm] (R-HSA-212414)	0.669	4
UniProt:Q9H944 MED20	1	MED20 [nucleoplasm] (R-HSA-212428)	0.643	4
UniProt:Q9NVC6 MED17	1	MED17 [nucleoplasm] (R-HSA-212401)	0.643	4
UniProt:Q9NWA0 MED9	1	MED9 [nucleoplasm] (R-HSA-556804)	0.643	3
UniProt:Q9NX70 MED29	1	MED29 [nucleoplasm] (R-HSA-556821)	0.643	5
UniProt:O75448 MED24	1	MED24 [nucleoplasm] (R-HSA-212331)	0.564	4
UniProt:O60244 MED14	1	MED14 [nucleoplasm] (R-HSA-212441)	0.564	3
UniProt:P24863 CCNC	1	CCNC [nucleoplasm] (R-HSA-212418)	0.527	3
UniProt:O95402 MED26	1	MED26 [nucleoplasm] (R-HSA-556783)	0.527	4
UniProt:Q15648 MED1	1	MED1 [nucleoplasm] (R-HSA-212445)	0.527	3
UniProt:O43513 MED7	1	MED7 [nucleoplasm] (R-HSA-212430)	0.527	3
UniProt:Q9Y3C7 MED31	1	MED31 [nucleoplasm] (R-HSA-212429)	0.527	2
UniProt:Q9BUE0 MED18	1	MED18 [nucleoplasm] (R-HSA-556826)	0.527	4
UniProt:Q15528 MED22	1	MED22 [nucleoplasm] (R-HSA-556779)	0.527	3
UniProt:Q9H204 MED28	1	MED28 [nucleoplasm] (R-HSA-6804546)	0.527	3
UniProt:Q99615 DNAJC7	2	DNAJC7 [nucleoplasm] (R-HSA-5255408) DNAJC7 [cytosol] (R-HSA-5252099)	0.527	2

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