Reactome | KCNIP3 [plasma membrane]

KCNIP3 [plasma membrane]

Stable Identifier

R-HSA-5577044

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Calsenilin, CSEN_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y2W7 KCNIP3

Gene Names

KCNIP3, CSEN, DREAM, KCHIP3

Chain

chain:1-256

Reference Genes

BioGPS Gene:30818 KCNIP3

COSMIC (genes):KCNIP3 KCNIP3

CTD Gene:30818 KCNIP3

dbSNP Gene:30818 KCNIP3

ENSEMBL:ENSG00000115041 KCNIP3

ENSEMBL_homo_sapiens_GENE:ENSG00000115041.14 KCNIP3

HGNC:15523 KCNIP3

KEGG Gene (Homo sapiens):30818 KCNIP3

Monarch:30818 KCNIP3

NCBI Gene:30818 KCNIP3

OMIM:604662 KCNIP3

UCSC:Q9Y2W7 KCNIP3

Reference Transcript

Other Identifiers

11725012_a_at

11753532_a_at

1555694_PM_a_at

1555694_a_at

16882895

228269_3p_x_at

228269_PM_x_at

228269_x_at

231774_PM_at

231774_at

2493995

2493996

2494014

2494024

2494025

2494026

2494033

2494034

2494035

2494043

2494045

2494046

2494048

2494049

2494050

2494051

2494052

2494065

30818

59964_at

8043552

A_23_P356004

GO:0000122

GO:0000978

GO:0001227

GO:0003677

GO:0005215

GO:0005267

GO:0005509

GO:0005515

GO:0005634

GO:0005737

GO:0005783

GO:0005794

GO:0005829

GO:0005886

GO:0006351

GO:0006355

GO:0006811

GO:0006813

GO:0006915

GO:0007165

GO:0008076

GO:0012501

GO:0015459

GO:0016020

GO:0023052

GO:0034220

GO:0034702

GO:0043226

GO:0046872

GO:0055085

GO:0071805

GO:0072659

GO:0098772

GO:0140110

GO:1901379

HMNXSV003008568

Hs.13228.0.A1_3p_at

Hs.13228.0.A1_3p_s_at

Hs.13228.0.A1_3p_x_at

Hs.13228.1.S2_3p_at

Hs2.13228.2.S1_3p_s_at

ILMN_1744403

ILMN_2262644

ILMN_2350823

PH_hs_0023663

TC02000572.hg

Participates

as a member of

KCNIP1-4 [plasma membrane] (Homo sapiens)

Other forms of this molecule

KCNIP3 [nucleoplasm]

Inferred To

ncs-7 [plasma membrane] (Caenorhabditis elegans)

kcnip3b [plasma membrane] (Danio rerio)

CG42683 [plasma membrane] (Drosophila melanogaster)

kcnip3 [plasma membrane] (Xenopus tropicalis)

KCNIP3 [plasma membrane] (Bos taurus)

KCNIP3 [plasma membrane] (Gallus gallus)

KCNIP3 [plasma membrane] (Mus musculus)

KCNIP3 [plasma membrane] (Rattus norvegicus)

KCNIP3 [plasma membrane] (Sus scrofa)

Cross References

RefSeq

NP_038462.1, NP_001030086.1

OpenTargets

ENSG00000115041

HPA

ENSG00000115041-KCNIP3

GeneCards

Q9Y2W7

Ensembl

ENSP00000295225, ENSG00000115041, ENSP00000417499, ENST00000468529, ENST00000295225

PRO

Q9Y2W7

Pharos - Targets

Q9Y2W7

PDB

2E6W

HMDB Protein

HMDBP02787

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8N6Q3 CD177	3	CD177 [specific granule membrane] (R-HSA-6800166) CD177 [plasma membrane] (R-HSA-202784) CD177 [tertiary granule membrane] (R-HSA-6800187)	0.781	9
UniProt:P40189 IL6ST	2	p-Y-IL6ST [plasma membrane] (R-HSA-8950439) IL6ST [plasma membrane] (R-HSA-448453)	0.601	7
UniProt:Q9BXU0 TEX12	1	TEX12 [nucleoplasm] (R-HSA-912441)	0.556	3
UniProt:O14843 FFAR3	1	FFAR3 [plasma membrane] (R-HSA-443951)	0.556	3
UniProt:Q7Z434 MAVS	2	MAVS [mitochondrial outer membrane] (R-HSA-913730) K48polyUb-MAVS [mitochondrial outer membrane] (R-HSA-983463)	0.556	3
UniProt:P05067 APP	20	APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [extracellular region] (R-HSA-49335) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-687) [extracellular region] (R-HSA-9010033) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(18-770) [endosome lumen] (R-HSA-5229077) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP [endoplasmic reticulum lumen] (R-HSA-8956696) APP(672-711) [extracellular region] (R-HSA-976740) APP(672-711) [cytosol] (R-HSA-877188) APP(672-713) [extracellular region] (R-HSA-879340)	0.556	3
UniProt:P08294 SOD3	3	SOD3 [Golgi lumen] (R-HSA-3697878) SOD3 (19-227) [extracellular region] (R-HSA-4837350) SOD3 [extracellular region] (R-HSA-3299690)	0.556	6

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