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HENMT1 [cytosol]
Stable Identifier
R-HSA-5601916
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Small RNA 2'-O-methyltransferase ecNumber2.1.1.n8/ecNumber, HENMT_HUMAN
Locations in the PathwayBrowser for interactor UniProt:O60749 SNX2
Expand all
Gene expression (Transcription) (Homo sapiens)
Gene Silencing by RNA (Homo sapiens)
PIWI-interacting RNA (piRNA) biogenesis (Homo sapiens)
HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 4xMeR-PIWIL1:piRNA:TDRD6:TDRKH (Homo sapiens)
HENMT1 [cytosol] (Homo sapiens)
HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 6xMeR-PIWIL2:piRNA:TDRD1:TDRD12:DDX4:ASZ:MOV10L1 (Homo sapiens)
HENMT1 [cytosol] (Homo sapiens)
HENMT1 methylates 2' hydroxyl at 3' end of piRNA in MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH (Homo sapiens)
HENMT1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q5T8I9 HENMT1
Gene Names
HENMT1, C1orf59
Chain
chain:1-393
Reference Genes
BioGPS Gene:113802 HENMT1
COSMIC (genes):HENMT1 HENMT1
CTD Gene:113802 HENMT1
dbSNP Gene:113802 HENMT1
ENSEMBL:ENSG00000162639 HENMT1
HGNC:26400 HENMT1
Monarch:113802 HENMT1
NCBI Gene:113802 HENMT1
OMIM:612178 HENMT1
UCSC:Q5T8I9 HENMT1
Reference Transcript
RefSeq:NM_001102592.1 HENMT1
RefSeq:NM_144584.2 HENMT1
Other Identifiers
113802
11720694_a_at
16690427
225841_PM_at
225841_at
2426677
2426678
2426679
2426680
2426681
2426682
2426683
2426684
2426685
2426686
2426687
2426688
2426689
2426690
2426691
2426692
2426693
2426694
2426695
2426696
2426697
2426698
2426699
2426700
2426701
55007_at
7918223
A_23_P309361
GE516328
GO:0001510
GO:0003723
GO:0003824
GO:0005515
GO:0005634
GO:0005737
GO:0008168
GO:0008171
GO:0008173
GO:0016740
GO:0030422
GO:0031047
GO:0032259
GO:0034587
GO:0043186
GO:0043226
GO:0046872
GO:0090486
GO:0140098
HMNXSV003057239
Hs.7962.0.A1_3p_at
ILMN_1682428
PH_hs_0000832
TC01002945.hg
Cross References
ENSEMBL
ENST00000370032
,
ENSP00000499017
,
ENSP00000385655
,
ENSP00000359049
,
ENST00000651461
,
ENST00000402983
OpenTargets
ENSG00000162639
IntEnz
2.1.1.386
HPA
ENSG00000162639-HENMT1
PRO
Q5T8I9
Pharos - Targets
Q5T8I9
HMDB Protein
HMDBP11779
PDB
4XCX
,
5WY0
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96LY2-2 Q96LY22
0.556
3
UniProt:Q0VD86 INCA1
0.556
3
UniProt:P14079 TAX
0.556
3
UniProt:Q12933 TRAF2
5
TRAF2 [cytosol]
(R-HSA-66370)
PolyUb-TRAF2 [cytosol]
(R-HSA-6782848)
K63polyUb-TRAF2 [cytosol]
(R-HSA-8862193)
K63polyUb-TRAF2 [nucleoplasm]
(R-HSA-8862194)
TRAF2 [nucleoplasm]
(R-HSA-8862199)
0.556
3
UniProt:O60749 SNX2
2
SNX2 [Golgi membrane]
(R-HSA-434333)
SNX2 [cytoplasmic vesicle membrane]
(R-HSA-434216)
0.527
2
UniProt:Q9BY49 PECR
2
PECR [cytosol]
(R-HSA-9033155)
PECR [peroxisomal membrane]
(R-HSA-6809577)
0.527
2
UniProt:Q9UNH7 SNX6
0.527
2
UniProt:Q9H903 MTHFD2L
1
MTHFD2L [mitochondrial matrix]
(R-HSA-6801350)
0.527
2
UniProt:Q9Y496 KIF3A
3
KIF3A [cilium]
(R-HSA-5610394)
KIF3A [cytosol]
(R-HSA-984767)
KIF3A [ciliary tip]
(R-HSA-5625377)
0.527
2
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