Reactome | IFT122 [cilium]

IFT122 [cilium]

Stable Identifier

R-HSA-5610379

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cilium

Synonyms

IFT-A 122, SPG, WDR10, WDR140, IFT A

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9HBG6 IFT122

Gene Names

IFT122, SPG, WDR10, WDR140

Chain

chain:1-1241

Reference Genes

BioGPS Gene:55764 IFT122

COSMIC (genes):IFT122 IFT122

CTD Gene:55764 IFT122

dbSNP Gene:55764 IFT122

ENSEMBL:ENSG00000163913.14 IFT122

HGNC:13556 IFT122

KEGG Gene (Homo sapiens):55764 IFT122

Monarch:55764 IFT122

NCBI Gene:55764 IFT122

OMIM:606045 IFT122

UCSC:Q9HBG6 IFT122

Reference Transcript

Other Identifiers

0002230372

0002510450

11721199_a_at

11748502_a_at

11748503_s_at

16945375

220744_PM_s_at

220744_s_at

2611311

2641637

2641642

2641647

2641668

2641669

2641670

2641671

2641677

2641678

2641681

2641682

2641684

2641686

2641691

2641692

2641693

2641694

2641698

2641699

2641700

2641701

2641702

2641703

2641704

2641708

2641711

2641712

2641713

2641716

2641717

2641721

2641723

2641727

2641732

2641733

2641739

2641742

2641743

2641744

2641751

2641752

2641756

2641757

2641758

2641759

2694503

54102_at

55764

8082523

A_14_P112088

A_14_P135646

GE55904

GO:0001843

GO:0005515

GO:0005622

GO:0005737

GO:0005815

GO:0005856

GO:0005929

GO:0007018

GO:0010172

GO:0016020

GO:0023052

GO:0030030

GO:0030991

GO:0032391

GO:0032991

GO:0035050

GO:0035721

GO:0036064

GO:0042073

GO:0042995

GO:0043226

GO:0044782

GO:0045879

GO:0048593

GO:0048856

GO:0060173

GO:0060271

GO:0061512

GO:0097542

GO:0097730

GO:1905515

HMNXSV003015698

HMNXSV003025438

ILMN_1666593

ILMN_1720724

ILMN_1742379

ILMN_2366177

PH_hs_0022326

TC03000692.hg

g8922747_3p_a_at

Participates

as a component of

as an input of

Assembly of IFT A complex (Homo sapiens)

as a member of

retrograde IFT regulators of Hh [cilium] (Homo sapiens)

Other forms of this molecule

IFT122 [ciliary tip]

Inferred To

IFT122 [cilium] (Bos taurus)

IFT122 [cilium] (Canis familiaris)

IFT122 [cilium] (Gallus gallus)

IFT122 [cilium] (Sus scrofa)

Ghost homologue of IFT122 [cilium] (Danio rerio)

Ift122 [cilium] (Mus musculus)

Ift122 [cilium] (Rattus norvegicus)

Oseg1 [cilium] (Drosophila melanogaster)

ift122 [cilium] (Xenopus tropicalis)

daf-10 [cilium] (Caenorhabditis elegans)

Cross References

RefSeq

NP_443716.1, NP_443711.2, NP_001267475.1, NP_001267470.1, NP_443715.1, NP_060732.2, NP_001267474.1

OpenTargets

ENSG00000163913

HPA

ENSG00000163913-IFT122

GeneCards

Q9HBG6

Ensembl

ENST00000348417, ENST00000347300, ENSG00000163913, ENSP00000324165, ENST00000349441, ENSP00000425536, ENSP00000324005, ENSP00000296266, ENSP00000422179, ENST00000296266, ENSP00000323973, ENST00000504021, ENST00000507564

PRO

Q9HBG6

Pharos - Targets

Q9HBG6

Orphanet

19245

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96RY7 IFT140	2	IFT140 [ciliary tip] (R-HSA-5625345) IFT140 [cilium] (R-HSA-5610382)	0.771	6
UniProt:O75386 TULP3	1	TULP3 [cilium] (R-HSA-5610445)	0.771	5
UniProt:Q8NEZ3 WDR19	2	WDR19 [ciliary tip] (R-HSA-5625347) WDR19 [cilium] (R-HSA-5610446)	0.74	6
UniProt:Q7Z4L5 TTC21B	2	TTC21B [ciliary tip] (R-HSA-5625349) TTC21B [cilium] (R-HSA-5610430)	0.704	5
UniProt:Q96FT9 IFT43	2	IFT43 [ciliary tip] (R-HSA-5625348) IFT43 [cilium] (R-HSA-5617619)	0.657	4
UniProt:Q9P2L0 WDR35	2	WDR35 [ciliary tip] (R-HSA-5625351) WDR35 [cilium] (R-HSA-5610448)	0.657	4
UniProt:Q9Q2G4 Q9Q2G4			0.558	3
UniProt:Q9P2L0-2 WDR35			0.527	2
UniProt:Q86VG3 IFTAP			0.527	2
UniProt:Q96FT9-2 IFT43			0.527	3
UniProt:Q01813 PFKP	1	PFKP [cytosol] (R-HSA-71452)	0.508	2
UniProt:Q9BU61 NDUFAF3	1	NDUFAF3 [mitochondrial inner membrane] (R-HSA-5689126)	0.508	2
UniProt:Q4G0X9 CCD40			0.508	2
UniProt:O00311 CDC7	1	CDC7 [nucleoplasm] (R-HSA-51781)	0.508	2