GLI2 is degraded by the proteasome

Stable Identifier
R-HSA-5610757
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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General
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After being ubiquitinated, the bulk of GLI2 is fully degraded by the proteasome; a small fraction of GLI2 may be converted to the repressor form after ubiquitination (Pan et al, 2006; Pan and Wang, 2007).
Literature References
Participants
Participates
Catalyst Activity

endopeptidase activity of 26S proteasome [cytosol]

Inferred From
Authored
Reviewed
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