Reactome | CTGF [extracellular region]

CTGF [extracellular region]

Stable Identifier

R-HSA-561148

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Connective tissue growth factor, CTGF_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P29279 CTGF

Gene Names

CTGF, CCN2, HCS24, IGFBP8

Chain

signal peptide:1-26, chain:27-349

Reference Genes

BioGPS Gene:1490 CTGF

CTD Gene:1490 CTGF

dbSNP Gene:1490 CTGF

ENSEMBL:ENSG00000118523 CTGF

ENSEMBL_homo_sapiens_GENE:ENSG00000118523.6 CTGF

HGNC:2500 CTGF

KEGG Gene (Homo sapiens):1490 CTGF

Monarch:1490 CTGF

NCBI Gene:1490 CTGF

OMIM:121009 CTGF

UCSC:P29279 CTGF

Reference Transcript

RefSeq:NM_001901.2 CTGF

Other Identifiers

11715440_a_at

11715441_a_at

11715442_s_at

1490

17023646

209101_PM_at

209101_at

2974331

2974332

2974333

2974334

2974335

2974337

2974338

2974343

2974344

2974346

2974347

2974348

36638_at

64342_at

8129562

A_23_P19663

GE60045

GO:0001502

GO:0001503

GO:0001525

GO:0001894

GO:0002062

GO:0005178

GO:0005515

GO:0005520

GO:0005576

GO:0005794

GO:0005886

GO:0007010

GO:0007155

GO:0007160

GO:0007165

GO:0007229

GO:0008201

GO:0008543

GO:0008544

GO:0009611

GO:0010629

GO:0016477

GO:0023052

GO:0030154

GO:0030312

GO:0030324

GO:0031012

GO:0032330

GO:0035988

GO:0043226

GO:0043231

GO:0045597

GO:0046330

GO:0048856

GO:0048870

GO:0050793

GO:0051496

GO:0061448

GO:0062023

GO:0070374

GO:0071897

GO:0072593

HMNXSV003006023

ILMN_2115125

M92934_at

PH_hs_0024819

TC06002112.hg

g180923_3p_s_at

Participates

as an output of

Expression of CTGF (Homo sapiens)

Cross References

RefSeq

NP_001892.1

GeneCards

P29279

HPA

ENSG00000118523-CCN2

Ensembl

ENST00000367976, ENSP00000356954, ENSG00000118523

PRO

P29279

Pharos - Targets

P29279

Orphanet

17583

HMDB Protein

HMDBP02161

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P03372 ESR1	10	p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) p-S167-ESR1 [cytosol] (R-HSA-9841254) Me260-ESR1 [cytosol] (R-HSA-9632177) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) ESR1 [nucleoplasm] (R-HSA-446168) ESR1 [cytosol] (R-HSA-9020968)	0.682	7
UniProt:P02751 FN1	10	FN1(32-2386) [platelet alpha granule lumen] (R-HSA-114620) FN1(32-271) [extracellular region] (R-HSA-3787935) FN1(272-2386) [extracellular region] (R-HSA-3788024) FN1(32-?) [extracellular region] (R-HSA-2533850) FN1(?-2386) [extracellular region] (R-HSA-2533841) FN1(32-1201)-p-7Y-ALK(1022-1620) fusion [plasma membrane] (R-HSA-9713462) FN1(32-1201)-ALK(1022-1620) fusion [plasma membrane] (R-HSA-9713459) p-FN1 [endoplasmic reticulum lumen] (R-HSA-8956937) FN1 [endoplasmic reticulum lumen] (R-HSA-8956708) FN1(32-2386) [extracellular region] (R-HSA-54851)	0.65	5
UniProt:Q92731 ESR2	5	PalmS-ESR2 [cytosol] (R-HSA-9020979) Me-PalmS-ESR2 [plasma membrane] (R-HSA-9637787) PalmS-ESR2 [plasma membrane] (R-HSA-9021059) ESR2 [nucleoplasm] (R-HSA-446165) ESR2 [cytosol] (R-HSA-9020970)	0.626	5
UniProt:Q6AZZ1 TRIM68	1	TRIM68 [cytosol] (R-HSA-5624350)	0.527	2
UniProt:Q92793 CREBBP	4	monoSUMO1-K998,K1033,K1056-CREBBP [nucleoplasm] (R-HSA-3927877) FOXO4-S-S-CREBBP [nucleoplasm] (R-HSA-9617684) CREBBP [cytosol] (R-HSA-9756493) CREBBP [nucleoplasm] (R-HSA-193545)	0.527	2
UniProt:Q09472 EP300	5	monoSUMO1-K1020,1024-EP300 [nucleoplasm] (R-HSA-3899306) Foxo4-S-S-EP300 [nucleoplasm] (R-HSA-9617720) FOXO4-S-S-EP300 [nucleoplasm] (R-HSA-9617691) p-S,T-EP300 [nucleoplasm] (R-HSA-8878072) EP300 [nucleoplasm] (R-HSA-381325)	0.527	2
UniProt:Q96BR5 COA7			0.527	2
UniProt:Q8NBE8 KLH23			0.527	2
UniProt:P98164 LRP2	2	LRP2 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869099) LRP2 [plasma membrane] (R-HSA-350083)	0.527	2

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