Reactome | CARD9 [cytosol]

CARD9 [cytosol]

Stable Identifier

R-HSA-561194

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Caspase recruitment domain-containing protein 9, CARD9_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q9Y2D8 ADIP

Expand all

External Reference Information

External Reference

UniProt:Q9H257 CARD9

Gene Names

CARD9

Chain

chain:1-536

Reference Genes

BioGPS Gene:64170 CARD9

COSMIC (genes):CARD9 CARD9

CTD Gene:64170 CARD9

dbSNP Gene:64170 CARD9

ENSEMBL:ENSG00000187796 CARD9

ENSEMBL_homo_sapiens_GENE:ENSG00000187796.16 CARD9

HGNC:16391 CARD9

KEGG Gene (Homo sapiens):64170 CARD9

Monarch:64170 CARD9

NCBI Gene:64170 CARD9

OMIM:607212 CARD9

UCSC:Q9H257 CARD9

Reference Transcript

Other Identifiers

11736526_a_at

17099901

220162_PM_s_at

220162_s_at

3229845

3229846

3229847

3229848

3229849

3229850

3229851

3229852

3229853

3229858

3229860

3229861

3229863

3229864

3229865

3229867

3229869

3229870

3229871

3229873

3229874

3229879

64170

81574_at

8165107

A_23_P500433

A_24_P180830

A_33_P3389573

GE82677

GO:0001819

GO:0002250

GO:0002376

GO:0002446

GO:0005515

GO:0005737

GO:0005829

GO:0005886

GO:0006351

GO:0006355

GO:0006954

GO:0007254

GO:0009410

GO:0009620

GO:0012501

GO:0016064

GO:0023052

GO:0032449

GO:0032494

GO:0032495

GO:0032663

GO:0032675

GO:0032680

GO:0032722

GO:0032725

GO:0032740

GO:0032755

GO:0032760

GO:0032874

GO:0032991

GO:0042802

GO:0042803

GO:0042981

GO:0043123

GO:0043280

GO:0043330

GO:0043621

GO:0045087

GO:0045089

GO:0046330

GO:0046872

GO:0048874

GO:0050700

GO:0050830

GO:0050896

GO:0051092

GO:0051260

GO:0051403

GO:0051607

GO:0060907

GO:0061760

GO:0065003

GO:0070374

GO:0098542

GO:1900017

GO:1904044

GO:2000318

HMNXSV003044985

ILMN_1712532

PH_hs_0035585

TC09002924.hg

g11641262_3p_a_at

Participates

as an input of

as a component of

PAMP:NOD oligomer:RIP2:CARD9 [cytosol] (Homo sapiens)

Other forms of this molecule

CARD9 [plasma membrane]

p-T231-CARD9 [plasma membrane]

Inferred To

card9 [cytosol] (Xenopus tropicalis)

CARD9 [cytosol] (Bos taurus)

CARD9 [cytosol] (Canis familiaris)

CARD9 [cytosol] (Gallus gallus)

CARD9 [cytosol] (Mus musculus)

CARD9 [cytosol] (Rattus norvegicus)

CARD9 [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_434701.1, NP_434700.2

OpenTargets

ENSG00000187796

GeneCards

Q9H257

HPA

ENSG00000187796-CARD9

Ensembl

ENST00000371734, ENSG00000187796, ENSP00000360797, ENSP00000360799, ENST00000489932, ENST00000371732, ENSP00000451368

PRO

Q9H257

Pharos - Targets

Q9H257

Orphanet

18982

PDB

6E26, 6N2M, 6E28, 6N2P, 6E25, 6E27

Interactors (63)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q3B820 F161A			0.666	4
UniProt:Q9Y4E8 USP25	1	USP15 [cytosol] (R-HSA-2173138)	0.666	4
UniProt:Q96GN5 CDA7L			0.666	4
UniProt:Q7Z3I7 ZN572			0.666	7
UniProt:Q08117 TLE5	1	AES [nucleoplasm] (R-HSA-4648963)	0.666	4
UniProt:P08727 KRT19	1	KRT19 [cytosol] (R-HSA-6809617)	0.666	4
UniProt:P36406 TRI23			0.666	4
UniProt:Q6NYC8 PPR18			0.666	4
UniProt:Q9P286 PAK5	2	PAK7 [plasma membrane] (R-HSA-211555) PAK5 [cytosol] (R-HSA-428459)	0.666	5
UniProt:Q6NT76 HMBX1			0.556	3
UniProt:Q9H5Z6 F124B			0.556	3
UniProt:Q2TBE0 CWF19L2	1	CWF19L2 [nucleoplasm] (R-HSA-9770846)	0.556	3
UniProt:Q99598 TSNAX	1	TSNAX [cytosol] (R-HSA-5216130)	0.556	5
UniProt:Q8TD31-3 CCHCR1			0.556	3
UniProt:Q8NHQ1 CEP70	1	CEP70 [cytosol] (R-HSA-380257)	0.556	3
UniProt:Q5VWN6-2 TASOR2			0.556	3
UniProt:Q9H2G9 BLZF1	1	BLZF1 [Golgi membrane] (R-HSA-2422372)	0.556	3
UniProt:Q8IWZ5 TRI42			0.556	3
UniProt:Q8IYA8 IHO1			0.556	3
UniProt:Q9Y247 FA50B			0.556	3
UniProt:Q53TS8 CTSRT			0.556	3
UniProt:Q8N8B7 TEANC			0.556	3
IntAct:EBI-10171679 386682			0.556	3
UniProt:Q14D33 RTP5			0.556	3
UniProt:Q13829 TNFAIP1	1	TNFAIP1 [cytosol] (R-HSA-9696531)	0.556	3
UniProt:Q96BZ8 LENG1	1	LENG1 [nucleoplasm] (R-HSA-9769590)	0.556	3
UniProt:Q15323 KRT31	1	KRT31 [cytosol] (R-HSA-6809616)	0.556	3
UniProt:P0DTD1-PRO_0000449633 REP			0.556	3
UniProt:A8K932 A8K932			0.556	3
UniProt:Q548N1 Q548N1			0.556	3
UniProt:Q8N3Z6 ZCHC7			0.556	3
UniProt:Q7Z6G3-2 NECAB2			0.556	3
UniProt:O75558 STX11			0.556	3
UniProt:Q6P1W5 CA094			0.556	3
UniProt:Q96PV4 PNMA5			0.556	3
UniProt:Q8IYX8-2 CEP57L1			0.556	3
UniProt:P56279 TCL1A			0.556	3
IntAct:EBI-10173330 386677			0.556	3
UniProt:O14639 ABLIM1	1	ABLIM1 [cytosol] (R-HSA-416771)	0.556	3
UniProt:O60573 EIF4E2	1	EIF4E2 [cytosol] (R-HSA-1678822)	0.556	3
UniProt:P40425 PBX2			0.556	3
UniProt:Q96SQ5 ZNF587	1	ZNF587 [nucleoplasm] (R-HSA-2127565)	0.556	3
UniProt:Q9Y2D8 ADIP			0.556	3
UniProt:Q9Y2J4-4 AMOTL2			0.556	5
UniProt:P63165 SUMO1	11	lysyl-G97-SUMO1 [plasma membrane] (R-HSA-9762382) lysyl-G97-SUMO1 [nucleolus] (R-HSA-9762385) lysyl-G97-SUMO1 [viral capsid] (R-HSA-9762386) UBE2I-G97-SUMO1 [cytosol] (R-HSA-4656941) lysyl-G97-SUMO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-9762380) lysyl-G97-SUMO1 [cytosol] (R-HSA-9762266) UBE2I-G97-SUMO1 [nucleoplasm] (R-HSA-3730622) UBA2-G97-SUMO1 [nucleoplasm] (R-HSA-3730616) SUMO1 [nucleoplasm] (R-HSA-877304) SUMO1(2-101) [nucleoplasm] (R-HSA-2990831) lysyl-G97-SUMO1 [nucleoplasm] (R-HSA-9761562)	0.556	3
UniProt:Q9BYV2 TRI54			0.556	3
UniProt:P60370 KRTAP10-5	1	KRTAP10-5 [cytosol] (R-HSA-6810260)	0.556	3
UniProt:Q7L273 KCTD9			0.556	3
UniProt:Q6A162 KRT40	1	KRT40 [cytosol] (R-HSA-6809605)	0.556	3
UniProt:P15622-3 ZNF250			0.556	3
UniProt:P50222 MEOX2			0.556	3
UniProt:Q9BRK4 LZTS2			0.556	3
UniProt:Q9UII6 DS13B			0.556	3
UniProt:Q8N720 ZNF655	1	ZNF655 [nucleoplasm] (R-HSA-2127575)	0.556	3
UniProt:Q8TAU3 ZNF417	1	ZNF417 [nucleoplasm] (R-HSA-1247539)	0.556	3
UniProt:Q8IXK0 PHC2	1	PHC2 [nucleoplasm] (R-HSA-389112)	0.556	3
UniProt:Q14134 TRIM29	1	TRIM29 [cytosol] (R-HSA-5624343)	0.556	3
UniProt:P25800 LMO1	1	LMO1 [nucleoplasm] (R-HSA-8956514)	0.556	3
UniProt:Q9UER7 DAXX	13	monoSUMO1-K630,K631-DAXX [nucleoplasm] (R-HSA-4086086) DAXX L98Vfs13 [nucleoplasm] (R-HSA-9673102) DAXX R48Vfs93 [nucleoplasm] (R-HSA-9673103) DAXX C74* [nucleoplasm] (R-HSA-9673096) DAXX S138* [nucleoplasm] (R-HSA-9673081) DAXX H26Tfs118 [nucleoplasm] (R-HSA-9673114) DAXX E104 [nucleoplasm] (R-HSA-9673078) DAXX E72Nfs72 [nucleoplasm] (R-HSA-9673110) DAXX C106 [nucleoplasm] (R-HSA-9673079) DAXX A103Sfs40 [nucleoplasm] (R-HSA-9673121) DAXX K56 [nucleoplasm] (R-HSA-9673089) DAXX A36Qfs*108 [nucleoplasm] (R-HSA-9673105) DAXX [nucleoplasm] (R-HSA-3222068)	0.556	3
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.556	3
UniProt:P55081 MFAP1	1	MFAP1 [nucleoplasm] (R-HSA-2396419)	0.556	3
UniProt:Q6ZU52 K0408			0.553	2
UniProt:O95999 BCL10	3	K48polyUb-BCL10 [cytosol] (R-HSA-8939329) BCL10 [cytosol] (R-HSA-202447) p-BCL10 [cytosol] (R-HSA-202488)	0.547	6

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