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RAB3IP [cytosol]
Stable Identifier
R-HSA-5617610
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
RABIN8
Locations in the PathwayBrowser for interactor UniProt:Q77UU1%20Q77UU1
Expand all
Organelle biogenesis and maintenance (Homo sapiens)
Cilium Assembly (Homo sapiens)
Anchoring of the basal body to the plasma membrane (Homo sapiens)
RAB11A:GTP-containing Golgi vesicles recruit RAB3IP (Homo sapiens)
RAB3IP [cytosol] (Homo sapiens)
Cargo trafficking to the periciliary membrane (Homo sapiens)
BBSome-mediated cargo-targeting to cilium (Homo sapiens)
BBSome binds RAB3IP (Homo sapiens)
RAB3IP [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96QF0 RAB3IP
Gene Names
RAB3IP, RABIN8
Chain
chain:1-476
Reference Genes
BioGPS Gene:117177 RAB3IP
COSMIC (genes):RAB3IP RAB3IP
CTD Gene:117177 RAB3IP
dbSNP Gene:117177 RAB3IP
ENSEMBL:ENSG00000127328 RAB3IP
ENSEMBL_homo_sapiens_GENE:ENSG00000127328.22 RAB3IP
HGNC:16508 RAB3IP
KEGG Gene (Homo sapiens):117177 RAB3IP
Monarch:117177 RAB3IP
NCBI Gene:117177 RAB3IP
OMIM:608686 RAB3IP
UCSC:Q96QF0 RAB3IP
Reference Transcript
RefSeq:XM_017018773.1 RAB3IP
RefSeq:NM_001278402.1 RAB3IP
RefSeq:XM_017018777.1 RAB3IP
RefSeq:NM_175623.3 RAB3IP
RefSeq:NM_001024647.3 RAB3IP
RefSeq:NM_022456.4 RAB3IP
RefSeq:NM_175625.3 RAB3IP
RefSeq:NM_175624.3 RAB3IP
RefSeq:XM_017018776.1 RAB3IP
Other Identifiers
117177
11728047_a_at
11728830_a_at
11728831_a_at
11758481_s_at
223471_PM_at
223471_at
231399_PM_at
231399_at
238526_PM_at
238526_at
238853_PM_at
238853_at
3421713
3421714
3421715
3421716
3421717
3421718
3421719
3421720
3421723
3421724
3421725
3421726
3421727
3421728
3421733
3421735
3421737
3421738
3421739
3421740
3421741
3421742
3421743
3421745
3421749
3421750
3421752
3421755
3421756
3421757
3421758
3421759
3421761
3421763
3421764
3421765
3421766
3421767
3421769
3421771
3421772
59738_at
64601_at
75270_at
7957072
82314_at
90016_at
A_14_P112701
A_14_P125625
A_21_P0007579
A_23_P128174
A_24_P93624
A_32_P180920
A_33_P3322450
GE542869
GE787272
GE87130
GO:0005085
GO:0005515
GO:0005634
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0005929
GO:0006612
GO:0006886
GO:0006887
GO:0006893
GO:0015031
GO:0016192
GO:0030027
GO:0031410
GO:0031982
GO:0033365
GO:0036064
GO:0042802
GO:0042995
GO:0043226
GO:0044782
GO:0048471
GO:0051020
GO:0051490
GO:0060271
GO:0070319
GO:0097711
GO:0098772
GO:1990635
HMNXSV003001389
HMNXSV003007006
HMNXSV003031827
HMNXSV003034260
Hs.140457.0.A1_3p_at
Hs.237062.0.S1_3p_at
Hs.283645.0.A1_3p_at
ILMN_1803197
PH_hs_0005732
TC12002441.hg
TC12003251.hg
g12803462_3p_at
p18869
Participates
as a member of
RAB8 GEFs [cytosol] (Homo sapiens)
as a component of
RAB3IP:BBSome [ciliary basal body] (Homo sapiens)
RAB3IP:RAB8A:GDP [cytosol] (Homo sapiens)
RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Homo sapiens)
RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Homo sapiens)
RAB3IP:RAB11A:GTP:Golgi-derived vesicle [Golgi-associated vesicle membrane] (Homo sapiens)
as an input of
BBSome binds RAB3IP (Homo sapiens)
RAB11A:GTP-containing Golgi vesicles recruit RAB3IP (Homo sapiens)
Inferred To
rab3ip [cytosol]
(Xenopus tropicalis)
RAB3IP [cytosol]
(Bos taurus)
RAB3IP [cytosol]
(Caenorhabditis elegans)
RAB3IP [cytosol]
(Canis familiaris)
RAB3IP [cytosol]
(Gallus gallus)
RAB3IP [cytosol]
(Sus scrofa)
SEC2 [cytosol]
(Saccharomyces cerevisiae)
Ghost homologue of RAB3IP [cytosol]
(Drosophila melanogaster)
Rab3ip [cytosol]
(Mus musculus)
Rab3ip [cytosol]
(Rattus norvegicus)
sec2 [cytosol]
(Schizosaccharomyces pombe)
zgc:110270 [cytosol]
(Danio rerio)
Cross References
RefSeq
NP_783322.1
,
NP_001265331.1
,
XP_016874266.1
,
XP_016874262.1
,
NP_001019818.1
,
NP_783323.1
,
NP_071901.2
,
NP_783324.1
,
XP_016874265.1
OpenTargets
ENSG00000127328
HPA
ENSG00000127328-RAB3IP
GeneCards
Q96QF0
Ensembl
ENSP00000448773
,
ENSP00000447300
,
ENST00000417413
,
ENST00000551641
,
ENSP00000448027
,
ENST00000552199
,
ENSP00000368092
,
ENSP00000247833
,
ENST00000553099
,
ENSG00000127328
,
ENSP00000419216
,
ENSP00000448944
,
ENST00000362025
,
ENSP00000355381
,
ENSP00000436304
,
ENST00000247833
,
ENST00000483530
,
ENST00000378815
,
ENST00000550536
PRO
Q96QF0
Pharos - Targets
Q96QF0
PDB
4UJ4
,
4LHY
,
4LHZ
,
4UJ5
,
4LHX
,
6F6P
,
4UJ3
Interactors (28)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8TBN0 RAB3IL1
1
RAB3IL1 [cytosol]
(R-HSA-8875296)
0.855
10
UniProt:P61006 RAB8A
6
GGC-RAB8A [cytoplasmic vesicle membrane]
(R-HSA-1445093)
RAB8A [recycling endosome membrane]
(R-HSA-8854145)
GGC-RAB8A [trans-Golgi network membrane]
(R-HSA-8876082)
RAB8A [Golgi membrane]
(R-HSA-2562535)
RAB8A [cytosol]
(R-HSA-5623399)
GGC-RAB8A [cytosol]
(R-HSA-8874063)
0.781
6
UniProt:P48553 TRAPPC10
1
TRAPPC10 [cytosol]
(R-HSA-5216159)
0.775
8
UniProt:Q9Y296 TRAPPC4
2
TRAPPC4 [plasma membrane]
(R-HSA-2682314)
TRAPPC4 [cytosol]
(R-HSA-5683764)
0.735
5
UniProt:Q96Q05 TRAPPC9
1
TRAPPC9 [cytosol]
(R-HSA-5683770)
0.723
6
UniProt:O43617 TRAPPC3
1
TRAPPC3 [cytosol]
(R-HSA-5683761)
0.704
4
UniProt:Q16385 SSX2
0.666
4
UniProt:O60568 PLOD3
1
PLOD3 [endoplasmic reticulum membrane]
(R-HSA-1981135)
0.666
4
UniProt:O75865 TRAPPC6A
1
TRAPPC6A [cytosol]
(R-HSA-5685733)
0.666
4
UniProt:Q9UL33 TRAPPC2L
1
TRAPPC2L [cytosol]
(R-HSA-5683759)
0.638
3
UniProt:Q9Y5R8 TRAPPC1
3
TRAPPC1 [extracellular region]
(R-HSA-6806180)
TRAPPC1 [azurophil granule lumen]
(R-HSA-6799360)
TRAPPC1 [cytosol]
(R-HSA-5683750)
0.638
3
UniProt:Q8N9M5 TM102
0.638
3
UniProt:P0DTD1-PRO_0000449633 REP
0.601
4
UniProt:P0DI81 TRAPPC2
1
TRAPPC2 [cytosol]
(R-HSA-5683757)
0.558
3
UniProt:P41227 NAA10
0.556
3
UniProt:O60437 PPL
2
PPL [cytosol]
(R-HSA-6810850)
PPL [cornified envelope]
(R-HSA-8847709)
0.556
3
UniProt:Q96T51 RUFY1
3
p-Y389,400-RUFY1 [cytosol]
(R-HSA-8871352)
RUFY1 [cytosol]
(R-HSA-8871374)
p-Y389,400-RUFY1 [early endosome membrane]
(R-HSA-5215951)
0.556
3
UniProt:Q9NX63 CHCHD3
3
CHCHD3 (MIC19) [mitochondrial inner membrane]
(R-HSA-8949583)
CHCHD3 [mitochondrial intermembrane space]
(R-HSA-8874907)
4xHC-CHCHD3 [mitochondrial intermembrane space]
(R-HSA-8874910)
0.556
3
UniProt:Q86VK4 ZN410
0.556
3
UniProt:P31947 SFN
1
SFN [cytosol]
(R-HSA-1445105)
0.556
3
UniProt:Q8N9N5 BANP
1
BANP [nucleoplasm]
(R-HSA-3221973)
0.556
3
UniProt:Q86V42 F124A
0.556
3
UniProt:Q6A162 KRT40
1
KRT40 [cytosol]
(R-HSA-6809605)
0.556
3
UniProt:P20336 RAB3A
9
GGC-RAB3A [secretory granule membrane]
(R-HSA-8875319)
GGC-RAB3A [cytosol]
(R-HSA-8870429)
RAB3A [cytosol]
(R-HSA-8870410)
RAB3A [secretory granule membrane]
(R-HSA-6804968)
RAB3A [clathrin-sculpted acetylcholine transport vesicle membrane]
(R-HSA-379365)
RAB3A [clathrin-sculpted glutamate transport vesicle membrane]
(R-HSA-210466)
RAB3A [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
(R-HSA-917743)
RAB3A [plasma membrane]
(R-HSA-210461)
RAB3A [clathrin-sculpted monoamine transport vesicle membrane]
(R-HSA-372512)
0.556
3
UniProt:P62258 YWHAE
1
YWHAE [cytosol]
(R-HSA-194368)
0.508
3
UniProt:Q9NR12 PDLIM7
1
PDLIM7 [cytosol]
(R-HSA-8855085)
0.508
2
UniProt:Q8IYB1 M21D2
0.508
2
UniProt:Q77UU1 Q77UU1
0.488
2
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