Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
HOXC4 [nucleoplasm]
Stable Identifier
R-HSA-5617871
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Homeobox protein Hox-C4, HXC4_HUMAN
Locations in the PathwayBrowser for interactor UniProt:P01023 A2M
Expand all
Developmental Biology (Homo sapiens)
Activation of HOX genes during differentiation (Homo sapiens)
Activation of anterior HOX genes in hindbrain development during early embryogenesis (Homo sapiens)
HOXC4 mRNA is translated (Homo sapiens)
HOXC4 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P09017 HOXC4
Gene Names
HOXC4, HOX3E
Chain
chain:1-264
Reference Genes
BioGPS Gene:3221 HOXC4
COSMIC (genes):HOXC4 HOXC4
CTD Gene:3221 HOXC4
dbSNP Gene:3221 HOXC4
ENSEMBL:ENSG00000198353 HOXC4
ENSEMBL_homo_sapiens_GENE:ENSG00000198353.8 HOXC4
HGNC:5126 HOXC4
KEGG Gene (Homo sapiens):3221 HOXC4
Monarch:3221 HOXC4
NCBI Gene:3221 HOXC4
OMIM:142974 HOXC4
UCSC:P09017 HOXC4
Reference Transcript
RefSeq:NM_014620.5 HOXC4
RefSeq:NM_153633.2 HOXC4
Other Identifiers
11725869_at
206194_PM_at
206194_at
3221
32480_at
3416307
3416308
3416333
3416334
3416335
3416336
3416337
3416338
51801_at
A_23_P150974
A_33_P3300975
GE59694
GO:0000785
GO:0000978
GO:0000981
GO:0001228
GO:0001501
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0006351
GO:0006355
GO:0009952
GO:0043226
GO:0045944
GO:0048562
GO:0048704
GO:0048856
GO:0051216
GO:0071837
GO:0140110
GO:1990837
HMNXSV003010456
HMNXSV003028455
Hs.50895.0.S2_3p_at
ILMN_1719975
ILMN_1757184
ILMN_1787334
TC12002373.hg
TC12003295.hg
TC12003298.hg
X07495_at
p27155
p33905
Participates
as an output of
HOXC4 mRNA is translated (Homo sapiens)
Cross References
RefSeq
NP_705897.1
,
NP_055435.2
OpenTargets
ENSG00000198353
GeneCards
P09017
HPA
ENSG00000198353-HOXC4
Ensembl
ENSG00000198353
,
ENST00000303406
,
ENSP00000399808
,
ENST00000430889
,
ENSP00000305973
PRO
P09017
Pharos - Targets
P09017
Interactors (32)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.666
16
UniProt:Q7Z699 SPRED1
2
SPRED1 [plasma membrane]
(R-HSA-5658225)
SPRED1 [cytosol]
(R-HSA-5654207)
0.556
3
UniProt:Q9NQG5 RPRD1B
1
RPRD1B [nucleoplasm]
(R-HSA-6814894)
0.556
3
UniProt:P50570-2 DNM2
0.556
3
UniProt:Q9Y3C5 RNF11
0.556
3
UniProt:P68400 CSNK2A1
2
CSNK2A1 [nucleoplasm]
(R-HSA-6805057)
CSNK2A1 [cytosol]
(R-HSA-201713)
0.556
3
UniProt:P49761 CLK3
0.556
3
UniProt:P01023 A2M
2
A2M [extracellular region]
(R-HSA-49291)
A2M [platelet alpha granule lumen]
(R-HSA-139834)
0.556
3
UniProt:Q8TB36 GDAP1
2
GDAP1 [peroxisomal membrane]
(R-HSA-9603788)
GDAP1 [cytosol]
(R-HSA-9603796)
0.556
3
UniProt:O60333-2 KIF1B
0.556
3
UniProt:P54253 ATX1
0.556
6
UniProt:Q9NQT4 EXOSC5
2
EXOSC5 [cytosol]
(R-HSA-429889)
EXOSC5 [nucleoplasm]
(R-HSA-6791550)
0.556
3
UniProt:O43639 NCK2
1
NCK2 [cytosol]
(R-HSA-204885)
0.556
3
UniProt:Q92993 KAT5
1
KAT5 [nucleoplasm]
(R-HSA-3321979)
0.556
3
UniProt:P37840 SNCA
5
SNCA A30P [cytosol]
(R-HSA-5658569)
SNCA [extracellular region]
(R-HSA-976954)
Ub-SNCA [cytosol]
(R-HSA-5660754)
p-S129-SNCA [cytosol]
(R-HSA-9836432)
SNCA [cytosol]
(R-HSA-5658500)
0.556
3
IntAct:EBI-25865403 EHD27213144
0.556
3
IntAct:EBI-25847655 CCSB
0.556
3
UniProt:Q16637 SMN1
2
SMN1 [nucleoplasm]
(R-HSA-191892)
SMN1 [cytosol]
(R-HSA-191839)
0.556
3
UniProt:Q8N2W9 PIAS4
2
PIAS4 [nucleoplasm]
(R-HSA-2993789)
monoSUMO1-K35-PIAS4 [nucleoplasm]
(R-HSA-3968415)
0.556
3
UniProt:P23284 PPIB
2
PPIB [endoplasmic reticulum lumen]
(R-HSA-1980262)
PPIB [cytosol]
(R-HSA-9728770)
0.556
3
UniProt:P00441 SOD1
5
SOD1 [extracellular region]
(R-HSA-350705)
2xHC-SOD1 [mitochondrial intermembrane space]
(R-HSA-3777108)
SOD1 [mitochondrial intermembrane space]
(R-HSA-3777082)
2xHC-SOD1 [cytosol]
(R-HSA-3299726)
SOD1 [cytosol]
(R-HSA-350697)
0.556
3
UniProt:Q86WV8 Q86WV8
0.556
3
UniProt:P28799 GRN
2
GRN [azurophil granule lumen]
(R-HSA-6799168)
GRN [extracellular region]
(R-HSA-6806217)
0.556
3
UniProt:G5E9A7 G5E9A7
0.556
3
UniProt:Q5SUL5 1A01
0.556
3
UniProt:Q15047-2 SETDB1
0.556
3
UniProt:P61981 YWHAG
1
YWHAG [cytosol]
(R-HSA-380312)
0.556
3
UniProt:Q8TAP4-4 LMO3
0.556
3
UniProt:P09067 HXB5
0.527
2
UniProt:Q9Y3P9 RABGAP1
1
RABGAP1 [cytosol]
(R-HSA-8854144)
0.527
3
UniProt:Q9BZ95 NSD3
1
WHSC1L1 [nucleoplasm]
(R-HSA-1183230)
0.508
2
UniProt:O43463 SUV39H1
1
SUV39H1 [nucleoplasm]
(R-HSA-427517)
0.508
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text