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GOPC:CFTR [Golgi-associated vesicle membrane]
Stable Identifier
R-HSA-5627082
Type
Complex
Species
Homo sapiens
Compartment
Golgi-associated vesicle membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases regulate CFTR trafficking (Homo sapiens)
GOPC promotes translocation of CFTR to lysosomes (Homo sapiens)
GOPC:CFTR [Golgi-associated vesicle membrane] (Homo sapiens)
RHOQ binds GOPC:CFTR (Homo sapiens)
GOPC:CFTR [Golgi-associated vesicle membrane] (Homo sapiens)
RHOQ:GTP:GOPC:CFTR [Golgi-associated vesicle membrane] (Homo sapiens)
GOPC:CFTR [Golgi-associated vesicle membrane] (Homo sapiens)
RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane (Homo sapiens)
RHOQ:GTP:GOPC:CFTR [Golgi-associated vesicle membrane] (Homo sapiens)
GOPC:CFTR [Golgi-associated vesicle membrane] (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RHOQ GTPase cycle (Homo sapiens)
RHOQ binds GOPC:CFTR (Homo sapiens)
GOPC:CFTR [Golgi-associated vesicle membrane] (Homo sapiens)
RHOQ:GTP:GOPC:CFTR [Golgi-associated vesicle membrane] (Homo sapiens)
GOPC:CFTR [Golgi-associated vesicle membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
15546864
Regulation of cystic fibrosis transmembrane regulator trafficking and protein expression by a Rho family small GTPase TC10
Cheng, J
,
Guggino, WB
,
Wang, H
J. Biol. Chem.
2005
Participants
components
CFTR dimer [Golgi-associated vesicle membrane]
(Homo sapiens)
GOPC dimer [Golgi-associated vesicle membrane]
(Homo sapiens)
Participates
as an input of
GOPC promotes translocation of CFTR to lysosomes (Homo sapiens)
RHOQ binds GOPC:CFTR (Homo sapiens)
as a component of
RHOQ:GTP:GOPC:CFTR [Golgi-associated vesicle membrane] (Homo sapiens)
This entity regulates
Positively
GOPC promotes translocation of CFTR to lysosomes
(Homo sapiens)
Inferred To
GOPC:CFTR [Golgi-associated vesicle membrane]
(Bos taurus)
GOPC:CFTR [Golgi-associated vesicle membrane]
(Caenorhabditis elegans)
GOPC:CFTR [Golgi-associated vesicle membrane]
(Canis familiaris)
GOPC:CFTR [Golgi-associated vesicle membrane]
(Danio rerio)
GOPC:CFTR [Golgi-associated vesicle membrane]
(Gallus gallus)
GOPC:CFTR [Golgi-associated vesicle membrane]
(Mus musculus)
GOPC:CFTR [Golgi-associated vesicle membrane]
(Rattus norvegicus)
GOPC:CFTR [Golgi-associated vesicle membrane]
(Sus scrofa)
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