MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9)

Stable Identifier
R-HSA-5634802
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
MECOM, PRDM16 methylate lysine-10 of replicative histone H3
ReviewStatus
5/5
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MECOM (KMT8E, PRDM3) and PRDM16 (KMT8F) are histone 3 lysine-10 (H3K9) methyltransferases responsible for cytoplasmic H3K9 mono-methylation.
Literature References
PubMed ID Title Journal Year
22939622 Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity

Jenuwein, T, Eisold, M, Pinheiro, I, Richter, FM, Reinberg, D, Fritzsch, C, Goyama, S, Son, J, Lachner, M, Mittler, G, Margueron, R, Kurokawa, M, Genoud, C, Shukeir, N

Cell 2012
Participants
Participates
Catalyst Activity

histone H3 methyltransferase activity of PRDM16, MECOM [cytosol]

Orthologous Events
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