TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane]

Stable Identifier
R-HSA-5637468
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
TRAIL:TRAIL receptor-1,2 Trimer:FADD:procaspase-8
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
17327223 Receptor-mediated endocytosis is not required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis

Cohen, GM, Pinkoski, MJ, Kohlhaas, SL, Sun, XM, Craxton, A

J. Biol. Chem. 2007
10894160 FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

Juo, P, Blenis, J, Weigand, MA, Sprick, MR, Rauch, CT, Rieser, E, Walczak, H, Krammer, PH

Immunity 2000
Participants
components
Participates
as an input of
as an output of
Inferred To
TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] (Bos taurus)
TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] (Gallus gallus)
TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] (Mus musculus)
TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] (Rattus norvegicus)
TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] (Sus scrofa)
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